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Utility of sepsis evaluation in infants 90 days of age or younger with fever and clinical bronchiolitis.
Pediatr Infect Dis J. 2003 Dec; 22(12):1053-6.PI

Abstract

OBJECTIVE

To identify the clinical utility of obtaining blood, urine and cerebrospinal fluid for bacterial culture among febrile infants <90 days of age with clinical bronchiolitis.

DESIGN

Retrospective chart review from 1995 to 2000.

SETTING

Urban emergency department of a tertiary children's hospital.

PARTICIPANTS

All infants <90 days of age presenting with fever and clinical bronchiolitis.

MAIN OUTCOME MEASURES

Result of the cultures of blood, urine and cerebrospinal fluid.

RESULTS

Of 3051 (11%) febrile infants, 329 met criteria for clinical bronchiolitis. Blood for culture was obtained from 309 (94%), urine for culture was obtained from 273 (83%) and cerebrospinal fluid for culture was obtained from 200 (61%). One hundred eighty-seven (57%) infants had all 3 specimens sent for culture. No cases of bacteremia [0%; 95% confidence interval (CI), 0, 1.1%] or meningitis (0%; 95% CI 0, 1.8%) occurred among these infants. However, 6 infants (2%; 95% CI 0.8, 5.7%), all male, had a culture of urine consistent with infection (4 Escherichia coli, 1 Staphylococcus aureus, 1 viridans streptococci).

CONCLUSION

The risk of bacteremia or meningitis among infants <90 days with fever and bronchiolitis is low in this age group. The risk of urinary tract infection in this age group is also low, but not negligible, at 2%.

Authors+Show Affiliations

Department of Medicine, Children's Hospital Boston, MA 02115, USA.No affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

14688564

Citation

Melendez, Elliot, and Marvin B. Harper. "Utility of Sepsis Evaluation in Infants 90 Days of Age or Younger With Fever and Clinical Bronchiolitis." The Pediatric Infectious Disease Journal, vol. 22, no. 12, 2003, pp. 1053-6.
Melendez E, Harper MB. Utility of sepsis evaluation in infants 90 days of age or younger with fever and clinical bronchiolitis. Pediatr Infect Dis J. 2003;22(12):1053-6.
Melendez, E., & Harper, M. B. (2003). Utility of sepsis evaluation in infants 90 days of age or younger with fever and clinical bronchiolitis. The Pediatric Infectious Disease Journal, 22(12), 1053-6.
Melendez E, Harper MB. Utility of Sepsis Evaluation in Infants 90 Days of Age or Younger With Fever and Clinical Bronchiolitis. Pediatr Infect Dis J. 2003;22(12):1053-6. PubMed PMID: 14688564.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Utility of sepsis evaluation in infants 90 days of age or younger with fever and clinical bronchiolitis. AU - Melendez,Elliot, AU - Harper,Marvin B, PY - 2003/12/23/pubmed PY - 2004/2/3/medline PY - 2003/12/23/entrez SP - 1053 EP - 6 JF - The Pediatric infectious disease journal JO - Pediatr Infect Dis J VL - 22 IS - 12 N2 - OBJECTIVE: To identify the clinical utility of obtaining blood, urine and cerebrospinal fluid for bacterial culture among febrile infants <90 days of age with clinical bronchiolitis. DESIGN: Retrospective chart review from 1995 to 2000. SETTING: Urban emergency department of a tertiary children's hospital. PARTICIPANTS: All infants <90 days of age presenting with fever and clinical bronchiolitis. MAIN OUTCOME MEASURES: Result of the cultures of blood, urine and cerebrospinal fluid. RESULTS: Of 3051 (11%) febrile infants, 329 met criteria for clinical bronchiolitis. Blood for culture was obtained from 309 (94%), urine for culture was obtained from 273 (83%) and cerebrospinal fluid for culture was obtained from 200 (61%). One hundred eighty-seven (57%) infants had all 3 specimens sent for culture. No cases of bacteremia [0%; 95% confidence interval (CI), 0, 1.1%] or meningitis (0%; 95% CI 0, 1.8%) occurred among these infants. However, 6 infants (2%; 95% CI 0.8, 5.7%), all male, had a culture of urine consistent with infection (4 Escherichia coli, 1 Staphylococcus aureus, 1 viridans streptococci). CONCLUSION: The risk of bacteremia or meningitis among infants <90 days with fever and bronchiolitis is low in this age group. The risk of urinary tract infection in this age group is also low, but not negligible, at 2%. SN - 0891-3668 UR - https://www.unboundmedicine.com/medline/citation/14688564/Utility_of_sepsis_evaluation_in_infants_90_days_of_age_or_younger_with_fever_and_clinical_bronchiolitis_ L2 - https://doi.org/10.1097/01.inf.0000101296.68993.4d DB - PRIME DP - Unbound Medicine ER -