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Predicted versus measured energy expenditure by continuous, online indirect calorimetry in ventilated, critically ill children during the early postinjury period.

Abstract

OBJECTIVE

Compare the energy expenditure, predicted by anthropometric equations, with that measured by continuous on-line indirect calorimetry in ventilated, critically ill children during the early postinjury period.

DESIGN

Prospective, clinical study.

SETTING

Pediatric intensive care unit of a pediatric university hospital.

PATIENTS

A total of 43 ventilated, critically ill children during the first 6 hrs after injury.

INTERVENTIONS

An indirect calorimeter was used to continuously measure the energy expenditure for 24 hrs.

MEASUREMENTS AND MAIN RESULTS

Clinical data collected were age, gender, actual and ideal weight, height, and body surface. Nutritional status was assessed by Waterlow and Shukla Index. Severity of illness was determined by Pediatric Risk of Mortality, Physiologic Stability Index, and Therapeutic Intervention Scoring System. Energy expenditure was measured (MEE) by continuous on-line indirect calorimetry for 24 hrs. Predicted Energy Expenditure (PEE) was calculated using the Harris-Benedict, Caldwell-Kennedy, Schofield, Food and Agriculture/World Health Organization/United Nation Union, Maffeis, Fleisch, Kleiber, Dreyer, and Hunter equations, using the actual and ideal weight. MEE and PEE were compared using paired Student's t-test, linear correlation (r), intraclass correlation coefficient (pI), and the Bland-Altman method. Mean MEE resulted in 674 +/- 384 kcal/day. Most of the predictive equations overestimated MEE in ventilated, critically ill children during the early postinjury period. MEE and PEE differed significantly (p<.05) except when the Caldwell-Kennedy and the Fleisch equations were used. r2 ranged from 0.78 to 0.81 (p<.05), and pI was excellent (>.75) for the Caldwell-Kennedy, Schofield, Food and Agriculture/World Health Organization/United Nation Union, Fleisch, and Kleiber equations. The Bland-Altman method showed poor accuracy; the Caldwell-Kennedy equation was the best predictor of energy expenditure (bias, 38 kcal/day; precision, +/- 179 kcal/day). The accuracy in the medical group was higher (pI range,.71-.94) than in surgical patients (pI range,.18-.75).

CONCLUSIONS

Predictive equations do not accurately predict energy expenditure in ventilated, critically ill children during the early postinjury period; if available, indirect calorimetry must be performed.

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  • Authors+Show Affiliations

    ,

    Pediatric Intensive Care Unit, Hospital Ramón y Cajal, Madrid, Spain. jvazquez.hrc@salud.madrid.org

    , ,

    Source

    MeSH

    Algorithms
    Calorimetry, Indirect
    Child, Preschool
    Energy Metabolism
    Female
    Humans
    Intensive Care Units, Pediatric
    Male
    Nutrition Assessment
    Predictive Value of Tests
    Prospective Studies
    Reference Values
    Reproducibility of Results
    Respiration, Artificial

    Pub Type(s)

    Evaluation Studies
    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    14697104

    Citation

    Vazquez Martinez, Jose Luis, et al. "Predicted Versus Measured Energy Expenditure By Continuous, Online Indirect Calorimetry in Ventilated, Critically Ill Children During the Early Postinjury Period." Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, vol. 5, no. 1, 2004, pp. 19-27.
    Vazquez Martinez JL, Martinez-Romillo PD, Diez Sebastian J, et al. Predicted versus measured energy expenditure by continuous, online indirect calorimetry in ventilated, critically ill children during the early postinjury period. Pediatr Crit Care Med. 2004;5(1):19-27.
    Vazquez Martinez, J. L., Martinez-Romillo, P. D., Diez Sebastian, J., & Ruza Tarrio, F. (2004). Predicted versus measured energy expenditure by continuous, online indirect calorimetry in ventilated, critically ill children during the early postinjury period. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 5(1), pp. 19-27.
    Vazquez Martinez JL, et al. Predicted Versus Measured Energy Expenditure By Continuous, Online Indirect Calorimetry in Ventilated, Critically Ill Children During the Early Postinjury Period. Pediatr Crit Care Med. 2004;5(1):19-27. PubMed PMID: 14697104.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Predicted versus measured energy expenditure by continuous, online indirect calorimetry in ventilated, critically ill children during the early postinjury period. AU - Vazquez Martinez,Jose Luis, AU - Martinez-Romillo,Paloma Dorao, AU - Diez Sebastian,Jesus, AU - Ruza Tarrio,Francisco, PY - 2003/12/31/pubmed PY - 2004/4/2/medline PY - 2003/12/31/entrez SP - 19 EP - 27 JF - Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies JO - Pediatr Crit Care Med VL - 5 IS - 1 N2 - OBJECTIVE: Compare the energy expenditure, predicted by anthropometric equations, with that measured by continuous on-line indirect calorimetry in ventilated, critically ill children during the early postinjury period. DESIGN: Prospective, clinical study. SETTING: Pediatric intensive care unit of a pediatric university hospital. PATIENTS: A total of 43 ventilated, critically ill children during the first 6 hrs after injury. INTERVENTIONS: An indirect calorimeter was used to continuously measure the energy expenditure for 24 hrs. MEASUREMENTS AND MAIN RESULTS: Clinical data collected were age, gender, actual and ideal weight, height, and body surface. Nutritional status was assessed by Waterlow and Shukla Index. Severity of illness was determined by Pediatric Risk of Mortality, Physiologic Stability Index, and Therapeutic Intervention Scoring System. Energy expenditure was measured (MEE) by continuous on-line indirect calorimetry for 24 hrs. Predicted Energy Expenditure (PEE) was calculated using the Harris-Benedict, Caldwell-Kennedy, Schofield, Food and Agriculture/World Health Organization/United Nation Union, Maffeis, Fleisch, Kleiber, Dreyer, and Hunter equations, using the actual and ideal weight. MEE and PEE were compared using paired Student's t-test, linear correlation (r), intraclass correlation coefficient (pI), and the Bland-Altman method. Mean MEE resulted in 674 +/- 384 kcal/day. Most of the predictive equations overestimated MEE in ventilated, critically ill children during the early postinjury period. MEE and PEE differed significantly (p<.05) except when the Caldwell-Kennedy and the Fleisch equations were used. r2 ranged from 0.78 to 0.81 (p<.05), and pI was excellent (>.75) for the Caldwell-Kennedy, Schofield, Food and Agriculture/World Health Organization/United Nation Union, Fleisch, and Kleiber equations. The Bland-Altman method showed poor accuracy; the Caldwell-Kennedy equation was the best predictor of energy expenditure (bias, 38 kcal/day; precision, +/- 179 kcal/day). The accuracy in the medical group was higher (pI range,.71-.94) than in surgical patients (pI range,.18-.75). CONCLUSIONS: Predictive equations do not accurately predict energy expenditure in ventilated, critically ill children during the early postinjury period; if available, indirect calorimetry must be performed. SN - 1529-7535 UR - https://www.unboundmedicine.com/medline/citation/14697104/Predicted_versus_measured_energy_expenditure_by_continuous_online_indirect_calorimetry_in_ventilated_critically_ill_children_during_the_early_postinjury_period_ L2 - http://Insights.ovid.com/pubmed?pmid=14697104 DB - PRIME DP - Unbound Medicine ER -