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Follicular mucinosis in alopecia areata.
Am J Dermatopathol. 1992 Dec; 14(6):542-5.AJ

Abstract

The pathological features of alopecia areata were described in association with those of follicular mucinosis in the scalp pathology of an 18-year-old woman. The immunohistochemical picture of the inflammatory infiltrate showed a high CD4/CD8 ratio (25:1), which was significantly different from the CD4/CD8 ratio in patients with alopecia areata. The abundance of helper/inducer cells along with the involvement of the upper part of the hair follicles might explain the development of follicular mucinosis in this case. Different possibilities were discussed, but the clinical presentation and the follow-up favored the clinical and pathological interpretation of alopecia areata with incidental findings of follicular mucinosis.

Authors+Show Affiliations

Fanti PA
Department of Dermatology, University of Bologna, Italy.
Tosti A
No affiliation info available
Morelli R
No affiliation info available
Cameli N
No affiliation info available
Sabattini E
No affiliation info available
Pileri S
No affiliation info available

MeSH

AdolescentAlopecia AreataFemaleHumansImmunohistochemistryMucinosis, FollicularScalpT-Lymphocyte Subsets

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

1471749

Citation

Fanti, P A., et al. "Follicular Mucinosis in Alopecia Areata." The American Journal of Dermatopathology, vol. 14, no. 6, 1992, pp. 542-5.
Fanti PA, Tosti A, Morelli R, et al. Follicular mucinosis in alopecia areata. Am J Dermatopathol. 1992;14(6):542-5.
Fanti, P. A., Tosti, A., Morelli, R., Cameli, N., Sabattini, E., & Pileri, S. (1992). Follicular mucinosis in alopecia areata. The American Journal of Dermatopathology, 14(6), 542-5.
Fanti PA, et al. Follicular Mucinosis in Alopecia Areata. Am J Dermatopathol. 1992;14(6):542-5. PubMed PMID: 1471749.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Follicular mucinosis in alopecia areata. AU - Fanti,P A, AU - Tosti,A, AU - Morelli,R, AU - Cameli,N, AU - Sabattini,E, AU - Pileri,S, PY - 1992/12/1/pubmed PY - 1992/12/1/medline PY - 1992/12/1/entrez SP - 542 EP - 5 JF - The American Journal of dermatopathology JO - Am J Dermatopathol VL - 14 IS - 6 N2 - The pathological features of alopecia areata were described in association with those of follicular mucinosis in the scalp pathology of an 18-year-old woman. The immunohistochemical picture of the inflammatory infiltrate showed a high CD4/CD8 ratio (25:1), which was significantly different from the CD4/CD8 ratio in patients with alopecia areata. The abundance of helper/inducer cells along with the involvement of the upper part of the hair follicles might explain the development of follicular mucinosis in this case. Different possibilities were discussed, but the clinical presentation and the follow-up favored the clinical and pathological interpretation of alopecia areata with incidental findings of follicular mucinosis. SN - 0193-1091 UR - https://www.unboundmedicine.com/medline/citation/1471749/Follicular_mucinosis_in_alopecia_areata_ DB - PRIME DP - Unbound Medicine ER -