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[The distributive characteristics of impaired glucose metabolism subcategories in Chinese adult population].
Zhonghua Yi Xue Za Zhi. 2003 Dec 25; 83(24):2128-31.ZY

Abstract

OBJECTIVE

To clarify the frequencies and clinical features of different impaired glucose metabolism subcategories in Chinese adults.

METHODS

A cross-sectional analysis of the data of 15,637 Chinese adults (aged >or= 25 years) who underwent standard 75 g oral glucose tolerance test from the National Diabetes Mellitus Survey (1994) was conducted. According to the 1999 WHO criteria for diabetes, the subjects were divided into 7 groups: normal glucose tolerance (NGT, FPG < 6.1 mmol/L and PG 2 h < 7.8 mmol/L), isolated impaired fasting glucose (i-IFG, 6.1 <or= FPG < 7.0 mmol/L and PG 2 h < 7.8 mmol/L), isolated impaired glucose tolerance (i-IGT, FPG < 6.1 mmol/L and 7.8 <or= PG 2 h < 11.1 mmol/L), combined i-IFG and i-IGT (IFG/IGT, 6.1 <or= FPG < 7.0 mmol/L and 7.8 <or= PG 2 h < 11.1 mmol/L), isolated fasting hyperglycemia (IFG, FPG >or= 7.0 mmol/L and PG 2 h < 11.1 mmol/L), isolated postload hyperglycemia (IPH, FPG < 7.0 mmol/L and PG 2 h >or= 11.1 mmol/L), and combined IFH and IPH (IFH/IPH, FPG >or= 7.0 mmol/L and PG 2 h >or= 11.1 mmol/L). The frequencies of the above subcategories were calculated and the clinical characteristics were compared.

RESULTS

(1) The frequencies of NGT, i-IFG, i-IGT, IFG/IGT, IFG, IPH, and IFH/IPH were 50.8%, 8.8%, 12.3%, 6.1%, 6.4%, 5.2%, and 10.4% respectively. (2) The frequencies of i-IGT, IFG/IGT, IPH, and IFH/IPH increased with age, whereas the frequencies of i-IFG and IFH tended to plateau in the age groups of 25 - 34 years and 55 - 64 years. (3) The mean age and blood pressure were significantly lower in the i-IFG group (vs the i-IGT or IFG/IGT group) and the IFH group (vs IPH or IFH/IPH group). Compared with the IPH group, the IFH group had higher homeostasis model assessment (HOMA) insulin resistance index (HOMA-IR) and lower beta cell function index (BCI).

CONCLUSIONS

i-IGT is the most common impaired glucose regulation (IGR) subcategory, and IFH/IPH is the most common diabetes subcategory in Chinese adults. The frequencies of i-IGT and IFH/IPH increase with age. The clinical features of i-IFG (IFG) are greatly different from those of i-IGT (IPH), suggesting that the determinants of FPG and PG 2 h differ.

Authors+Show Affiliations

Department of Endocrinology, China-Japan Friendship Hospital, Beijing 100029, China.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

chi

PubMed ID

14720420

Citation

Yang, Zhao-jun, et al. "[The Distributive Characteristics of Impaired Glucose Metabolism Subcategories in Chinese Adult Population]." Zhonghua Yi Xue Za Zhi, vol. 83, no. 24, 2003, pp. 2128-31.
Yang ZJ, Yang WY, Li GW, et al. [The distributive characteristics of impaired glucose metabolism subcategories in Chinese adult population]. Zhonghua Yi Xue Za Zhi. 2003;83(24):2128-31.
Yang, Z. J., Yang, W. Y., & Li, G. W. (2003). [The distributive characteristics of impaired glucose metabolism subcategories in Chinese adult population]. Zhonghua Yi Xue Za Zhi, 83(24), 2128-31.
Yang ZJ, et al. [The Distributive Characteristics of Impaired Glucose Metabolism Subcategories in Chinese Adult Population]. Zhonghua Yi Xue Za Zhi. 2003 Dec 25;83(24):2128-31. PubMed PMID: 14720420.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [The distributive characteristics of impaired glucose metabolism subcategories in Chinese adult population]. AU - Yang,Zhao-jun, AU - Yang,Wen-ying, AU - Li,Guang-wei, AU - ,, PY - 2004/1/15/pubmed PY - 2004/5/7/medline PY - 2004/1/15/entrez SP - 2128 EP - 31 JF - Zhonghua yi xue za zhi JO - Zhonghua Yi Xue Za Zhi VL - 83 IS - 24 N2 - OBJECTIVE: To clarify the frequencies and clinical features of different impaired glucose metabolism subcategories in Chinese adults. METHODS: A cross-sectional analysis of the data of 15,637 Chinese adults (aged >or= 25 years) who underwent standard 75 g oral glucose tolerance test from the National Diabetes Mellitus Survey (1994) was conducted. According to the 1999 WHO criteria for diabetes, the subjects were divided into 7 groups: normal glucose tolerance (NGT, FPG < 6.1 mmol/L and PG 2 h < 7.8 mmol/L), isolated impaired fasting glucose (i-IFG, 6.1 <or= FPG < 7.0 mmol/L and PG 2 h < 7.8 mmol/L), isolated impaired glucose tolerance (i-IGT, FPG < 6.1 mmol/L and 7.8 <or= PG 2 h < 11.1 mmol/L), combined i-IFG and i-IGT (IFG/IGT, 6.1 <or= FPG < 7.0 mmol/L and 7.8 <or= PG 2 h < 11.1 mmol/L), isolated fasting hyperglycemia (IFG, FPG >or= 7.0 mmol/L and PG 2 h < 11.1 mmol/L), isolated postload hyperglycemia (IPH, FPG < 7.0 mmol/L and PG 2 h >or= 11.1 mmol/L), and combined IFH and IPH (IFH/IPH, FPG >or= 7.0 mmol/L and PG 2 h >or= 11.1 mmol/L). The frequencies of the above subcategories were calculated and the clinical characteristics were compared. RESULTS: (1) The frequencies of NGT, i-IFG, i-IGT, IFG/IGT, IFG, IPH, and IFH/IPH were 50.8%, 8.8%, 12.3%, 6.1%, 6.4%, 5.2%, and 10.4% respectively. (2) The frequencies of i-IGT, IFG/IGT, IPH, and IFH/IPH increased with age, whereas the frequencies of i-IFG and IFH tended to plateau in the age groups of 25 - 34 years and 55 - 64 years. (3) The mean age and blood pressure were significantly lower in the i-IFG group (vs the i-IGT or IFG/IGT group) and the IFH group (vs IPH or IFH/IPH group). Compared with the IPH group, the IFH group had higher homeostasis model assessment (HOMA) insulin resistance index (HOMA-IR) and lower beta cell function index (BCI). CONCLUSIONS: i-IGT is the most common impaired glucose regulation (IGR) subcategory, and IFH/IPH is the most common diabetes subcategory in Chinese adults. The frequencies of i-IGT and IFH/IPH increase with age. The clinical features of i-IFG (IFG) are greatly different from those of i-IGT (IPH), suggesting that the determinants of FPG and PG 2 h differ. SN - 0376-2491 UR - https://www.unboundmedicine.com/medline/citation/14720420/[The_distributive_characteristics_of_impaired_glucose_metabolism_subcategories_in_Chinese_adult_population]_ L2 - http://journal.yiigle.com/LinkIn.do?linkin_type=pubmed&amp;issn=0376-2491&amp;year=2003&amp;vol=83&amp;issue=24&amp;fpage=2128 DB - PRIME DP - Unbound Medicine ER -