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Antioxidant responses to benzo[a]pyrene and Aroclor 1254 exposure in the green-lipped mussel, Perna viridis.
Environ Pollut. 2004; 128(3):393-403.EP

Abstract

In this study, the green-lipped mussel, Perna viridis (L.), was exposed to two concentrations of benzo[a]pyrene (B[a]P) (0.3 microg l(-1); 3 microg l(-1)) and two concentrations of Aroclor 1254 (0.5 microg l(-1); 5 microg l(-1)). In addition, a mixture of the contaminants was used (0.3 microg l(-1) B[a]P+0.5 microg l(-1) Aroclor 1254; 3 microg l(-1) B[a]P+5 microg l(-1) Aroclor 1254). All concentrations were nominal. A suite of enzymes [glutathione S transferase (GST), superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR)], glutathione (GSH) level and lipid peroxidation (LPO) in the mussel gill and hepatopancreas were monitored over 18 days. CAT and GSH in gill tissue were positively correlated with concentration of Aroclor 1254. Activity of hepatic GST and SOD was significantly related to body burden of Aroclor 1254. LPO, GR and GPx in gill and hepatopancreas and hepatic GST were positively correlated with B[a]P concentration. The results indicate the importance of using biomarkers specific to the type of contaminant(s) that are likely to be present. Controlled laboratory experiments, such as this study, are useful in ascertaining biomarkers suitable for use with complex contaminant mixtures in the marine environment.

Authors+Show Affiliations

Department of Biology and Chemistry, Centre for Coastal Pollution and Conservation, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

14720481

Citation

Cheung, C C C., et al. "Antioxidant Responses to Benzo[a]pyrene and Aroclor 1254 Exposure in the Green-lipped Mussel, Perna Viridis." Environmental Pollution (Barking, Essex : 1987), vol. 128, no. 3, 2004, pp. 393-403.
Cheung CC, Siu WH, Richardson BJ, et al. Antioxidant responses to benzo[a]pyrene and Aroclor 1254 exposure in the green-lipped mussel, Perna viridis. Environ Pollut. 2004;128(3):393-403.
Cheung, C. C., Siu, W. H., Richardson, B. J., De Luca-Abbott, S. B., & Lam, P. K. (2004). Antioxidant responses to benzo[a]pyrene and Aroclor 1254 exposure in the green-lipped mussel, Perna viridis. Environmental Pollution (Barking, Essex : 1987), 128(3), 393-403.
Cheung CC, et al. Antioxidant Responses to Benzo[a]pyrene and Aroclor 1254 Exposure in the Green-lipped Mussel, Perna Viridis. Environ Pollut. 2004;128(3):393-403. PubMed PMID: 14720481.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antioxidant responses to benzo[a]pyrene and Aroclor 1254 exposure in the green-lipped mussel, Perna viridis. AU - Cheung,C C C, AU - Siu,W H L, AU - Richardson,B J, AU - De Luca-Abbott,S B, AU - Lam,P K S, PY - 2003/06/06/received PY - 2003/09/12/accepted PY - 2004/1/15/pubmed PY - 2008/1/4/medline PY - 2004/1/15/entrez SP - 393 EP - 403 JF - Environmental pollution (Barking, Essex : 1987) JO - Environ Pollut VL - 128 IS - 3 N2 - In this study, the green-lipped mussel, Perna viridis (L.), was exposed to two concentrations of benzo[a]pyrene (B[a]P) (0.3 microg l(-1); 3 microg l(-1)) and two concentrations of Aroclor 1254 (0.5 microg l(-1); 5 microg l(-1)). In addition, a mixture of the contaminants was used (0.3 microg l(-1) B[a]P+0.5 microg l(-1) Aroclor 1254; 3 microg l(-1) B[a]P+5 microg l(-1) Aroclor 1254). All concentrations were nominal. A suite of enzymes [glutathione S transferase (GST), superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR)], glutathione (GSH) level and lipid peroxidation (LPO) in the mussel gill and hepatopancreas were monitored over 18 days. CAT and GSH in gill tissue were positively correlated with concentration of Aroclor 1254. Activity of hepatic GST and SOD was significantly related to body burden of Aroclor 1254. LPO, GR and GPx in gill and hepatopancreas and hepatic GST were positively correlated with B[a]P concentration. The results indicate the importance of using biomarkers specific to the type of contaminant(s) that are likely to be present. Controlled laboratory experiments, such as this study, are useful in ascertaining biomarkers suitable for use with complex contaminant mixtures in the marine environment. SN - 0269-7491 UR - https://www.unboundmedicine.com/medline/citation/14720481/Antioxidant_responses_to_benzo[a]pyrene_and_Aroclor_1254_exposure_in_the_green_lipped_mussel_Perna_viridis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0269749103003580 DB - PRIME DP - Unbound Medicine ER -