Tags

Type your tag names separated by a space and hit enter

Cerebral correlates of alerting, orienting and reorienting of visuospatial attention: an event-related fMRI study.
Neuroimage 2004; 21(1):318-28N

Abstract

The identification of brain systems contributing to different aspects of visuospatial attention is of both clinical and theoretical interest. Cued target detection tasks provide a simple means to dissociate attentional subcomponents, such as alerting, orienting or reorienting of attention. Event-related functional magnetic resonance imaging (fMRI) was used to study neural correlates of these distinct attentional processes. Volunteers were scanned while performing a centrally cued target detection task. Four different types of trials (no cue, neutral cue, valid cue and invalid cue trials) with targets appearing either in the right or left hemifield were randomly intermixed. Behaviourally, the data provided evidence for alerting, spatial orienting and reorienting of attention. Neurally, the alerting effect was seen in bilaterally increased extrastriatal blood oxygenation level-dependent (BOLD) activity in neutral as compared to no cue trials. Neural correlates of spatial orienting were seen in anterior cingulate cortex, which was more active during valid as compared to neutral cue trials. Neural correlates of reorienting of attention, that is, higher BOLD activity to invalid as compared to validly cued trials were evident in several brain regions including left and right intraparietal sulcus, right temporo-parietal junction and middle frontal gyrus bilaterally. The data suggest that frontal and parietal regions are specifically involved in reorienting rather than orienting attention to a spatial position. Alerting effects were seen in extrastriate regions which suggest that increased phasic alertness results in a top-down modulation of neural activity in visual processing areas.

Authors+Show Affiliations

Institute of Medicine, Research Centre Jülich, 52425, Jülich, Germany. c.thiel@fz-juelich.deNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

14741670

Citation

Thiel, Christiane M., et al. "Cerebral Correlates of Alerting, Orienting and Reorienting of Visuospatial Attention: an Event-related fMRI Study." NeuroImage, vol. 21, no. 1, 2004, pp. 318-28.
Thiel CM, Zilles K, Fink GR. Cerebral correlates of alerting, orienting and reorienting of visuospatial attention: an event-related fMRI study. Neuroimage. 2004;21(1):318-28.
Thiel, C. M., Zilles, K., & Fink, G. R. (2004). Cerebral correlates of alerting, orienting and reorienting of visuospatial attention: an event-related fMRI study. NeuroImage, 21(1), pp. 318-28.
Thiel CM, Zilles K, Fink GR. Cerebral Correlates of Alerting, Orienting and Reorienting of Visuospatial Attention: an Event-related fMRI Study. Neuroimage. 2004;21(1):318-28. PubMed PMID: 14741670.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cerebral correlates of alerting, orienting and reorienting of visuospatial attention: an event-related fMRI study. AU - Thiel,Christiane M, AU - Zilles,Karl, AU - Fink,Gereon R, PY - 2004/1/27/pubmed PY - 2004/3/27/medline PY - 2004/1/27/entrez SP - 318 EP - 28 JF - NeuroImage JO - Neuroimage VL - 21 IS - 1 N2 - The identification of brain systems contributing to different aspects of visuospatial attention is of both clinical and theoretical interest. Cued target detection tasks provide a simple means to dissociate attentional subcomponents, such as alerting, orienting or reorienting of attention. Event-related functional magnetic resonance imaging (fMRI) was used to study neural correlates of these distinct attentional processes. Volunteers were scanned while performing a centrally cued target detection task. Four different types of trials (no cue, neutral cue, valid cue and invalid cue trials) with targets appearing either in the right or left hemifield were randomly intermixed. Behaviourally, the data provided evidence for alerting, spatial orienting and reorienting of attention. Neurally, the alerting effect was seen in bilaterally increased extrastriatal blood oxygenation level-dependent (BOLD) activity in neutral as compared to no cue trials. Neural correlates of spatial orienting were seen in anterior cingulate cortex, which was more active during valid as compared to neutral cue trials. Neural correlates of reorienting of attention, that is, higher BOLD activity to invalid as compared to validly cued trials were evident in several brain regions including left and right intraparietal sulcus, right temporo-parietal junction and middle frontal gyrus bilaterally. The data suggest that frontal and parietal regions are specifically involved in reorienting rather than orienting attention to a spatial position. Alerting effects were seen in extrastriate regions which suggest that increased phasic alertness results in a top-down modulation of neural activity in visual processing areas. SN - 1053-8119 UR - https://www.unboundmedicine.com/medline/citation/14741670/Cerebral_correlates_of_alerting_orienting_and_reorienting_of_visuospatial_attention:_an_event_related_fMRI_study_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1053811903005548 DB - PRIME DP - Unbound Medicine ER -