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Chemical composition and microbicidal activity of extracts from Brazilian and Bulgarian propolis.

Abstract

AIMS

The chemical composition of ethanol extracts from a Brazilian (Et-Bra) and a Bulgarian (Et-Blg) propolis, and their activity against the protozoan Trypanosoma cruzi, several fungi and bacteria species were determined.

METHODS AND RESULTS

The chemical composition was determined by high temperature high resolution gas chromatography coupled to mass spectrometry. Microbiological activity was assayed in vitro against T. cruzi, Candida albicans, Sporothrix schenckii, Paracoccidioides brasiliensis, Neisseria meningitidis, Streptococcus pneumoniae and Staphylococcus aureus.

CONCLUSIONS

Et-Bra and Et-Blg, although with totally distinct compositions, were active against T. cruzi and the three species of fungi. Et-Blg was more effective than Et-Bra against bacteria, particularly N. meningitidis and Strep. pneumoniae.

SIGNIFICANCE AND IMPACT OF THE STUDY

Although with different classes of components, both propolis extracts showed microbicidal activity. For the bactericidal activity it was possible to establish a positive correlation with the high content of flavonoids of the Bulgarian extract.

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  • Authors+Show Affiliations

    ,

    Dept. de Ultra-estrutura e Biologia Celular Dept. de Micologia Dept. de Bacteriologia, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil. solange@ioc.fiocruz.br

    , , , , ,

    Source

    MeSH

    Animals
    Anti-Infective Agents
    Bacteria
    Brazil
    Bulgaria
    Candida albicans
    Flavonoids
    Fungi
    Gas Chromatography-Mass Spectrometry
    Microbial Sensitivity Tests
    Neisseria meningitidis
    Paracoccidioides
    Parasitic Sensitivity Tests
    Propolis
    Sporothrix
    Staphylococcus aureus
    Streptococcus pneumoniae
    Trypanosoma cruzi

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    14746537

    Citation

    Salomão, K, et al. "Chemical Composition and Microbicidal Activity of Extracts From Brazilian and Bulgarian Propolis." Letters in Applied Microbiology, vol. 38, no. 2, 2004, pp. 87-92.
    Salomão K, Dantas AP, Borba CM, et al. Chemical composition and microbicidal activity of extracts from Brazilian and Bulgarian propolis. Lett Appl Microbiol. 2004;38(2):87-92.
    Salomão, K., Dantas, A. P., Borba, C. M., Campos, L. C., Machado, D. G., Aquino Neto, F. R., & de Castro, S. L. (2004). Chemical composition and microbicidal activity of extracts from Brazilian and Bulgarian propolis. Letters in Applied Microbiology, 38(2), pp. 87-92.
    Salomão K, et al. Chemical Composition and Microbicidal Activity of Extracts From Brazilian and Bulgarian Propolis. Lett Appl Microbiol. 2004;38(2):87-92. PubMed PMID: 14746537.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Chemical composition and microbicidal activity of extracts from Brazilian and Bulgarian propolis. AU - Salomão,K, AU - Dantas,A P, AU - Borba,C M, AU - Campos,L C, AU - Machado,D G, AU - Aquino Neto,F R, AU - de Castro,S L, PY - 2004/1/30/pubmed PY - 2004/4/9/medline PY - 2004/1/30/entrez SP - 87 EP - 92 JF - Letters in applied microbiology JO - Lett. Appl. Microbiol. VL - 38 IS - 2 N2 - AIMS: The chemical composition of ethanol extracts from a Brazilian (Et-Bra) and a Bulgarian (Et-Blg) propolis, and their activity against the protozoan Trypanosoma cruzi, several fungi and bacteria species were determined. METHODS AND RESULTS: The chemical composition was determined by high temperature high resolution gas chromatography coupled to mass spectrometry. Microbiological activity was assayed in vitro against T. cruzi, Candida albicans, Sporothrix schenckii, Paracoccidioides brasiliensis, Neisseria meningitidis, Streptococcus pneumoniae and Staphylococcus aureus. CONCLUSIONS: Et-Bra and Et-Blg, although with totally distinct compositions, were active against T. cruzi and the three species of fungi. Et-Blg was more effective than Et-Bra against bacteria, particularly N. meningitidis and Strep. pneumoniae. SIGNIFICANCE AND IMPACT OF THE STUDY: Although with different classes of components, both propolis extracts showed microbicidal activity. For the bactericidal activity it was possible to establish a positive correlation with the high content of flavonoids of the Bulgarian extract. SN - 0266-8254 UR - https://www.unboundmedicine.com/medline/citation/14746537/Chemical_composition_and_microbicidal_activity_of_extracts_from_Brazilian_and_Bulgarian_propolis_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0266-8254&date=2004&volume=38&issue=2&spage=87 DB - PRIME DP - Unbound Medicine ER -