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[Seasonal variations in admissions for acute myocardial infarction. The PRIMVAC study].
Rev Esp Cardiol. 2004 Jan; 57(1):12-9.RE

Abstract

INTRODUCTION AND OBJECTIVES

Some authors have described seasonal variations in the incidence of acute myocardial infarction. The aim of this study was to determine the existence of seasonal rhythms in admissions for acute myocardial infarction to coronary care units, and in mortality, and to analyze the influence of age on environmental factors.

PATIENTS AND METHOD

The study included a total of 8400 consecutive patients with acute myocardial infarction admitted to 12 coronary care units in the PRIMVAC registry from January 1995 to December 1999. Seasonal rhythms were analyzed with the time series method and the Cosinor regression equation. The influence of age was analyzed with the chi 2 test.

RESULTS

The total number of admissions increased in winter and decreased in summer. The highest peak (acrophase) occurred in winter, with 2183 cases (r2=0.91), specifically in February, with 742 cases (r2=0.66). The age of the patients conditioned seasonal variations (P=.006), and the influence was statistically significant for patients over 65 years of age. Changes in mortality with time did not reach statistical significance.

CONCLUSIONS

A seasonal rhythm in admissions for acute myocardial infarction was found, with an increase in winter and a decrease in summer. Age conditioned the effect of environmental factors on acute myocardial infarction, and patients aged 65 years or older were more sensitive to mechanisms that led to increases in admissions in winter.

Authors+Show Affiliations

González Hernández E
Unidad de Cuidados Intensivos. Hospital La Plana. Villareal. Castellón. España. gonzalez_enr@gva.es
Cabadés O'Callaghan A
No affiliation info available
Cebrián Doménech J
No affiliation info available
López Merino V
No affiliation info available
Sanjuán Mañez R
No affiliation info available
Echánove Errazti I
No affiliation info available
Valencia Martín J
No affiliation info available
Bertomeu Martínez V
No affiliation info available
Investigadores del estudio PRIMVAC
No affiliation info available

MeSH

Age DistributionAgedCold TemperatureHumansIncidenceMiddle AgedMyocardial InfarctionRegistriesRegression AnalysisSeasonsSpain

Pub Type(s)

Comparative Study
English Abstract
Journal Article
Multicenter Study

Language

spa

PubMed ID

14746713

Citation

González Hernández, Enrique, et al. "[Seasonal Variations in Admissions for Acute Myocardial Infarction. the PRIMVAC Study]." Revista Espanola De Cardiologia, vol. 57, no. 1, 2004, pp. 12-9.
González Hernández E, Cabadés O'Callaghan A, Cebrián Doménech J, et al. [Seasonal variations in admissions for acute myocardial infarction. The PRIMVAC study]. Rev Esp Cardiol. 2004;57(1):12-9.
González Hernández, E., Cabadés O'Callaghan, A., Cebrián Doménech, J., López Merino, V., Sanjuán Mañez, R., Echánove Errazti, I., Valencia Martín, J., & Bertomeu Martínez, V. (2004). [Seasonal variations in admissions for acute myocardial infarction. The PRIMVAC study]. Revista Espanola De Cardiologia, 57(1), 12-9.
González Hernández E, et al. [Seasonal Variations in Admissions for Acute Myocardial Infarction. the PRIMVAC Study]. Rev Esp Cardiol. 2004;57(1):12-9. PubMed PMID: 14746713.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Seasonal variations in admissions for acute myocardial infarction. The PRIMVAC study]. AU - González Hernández,Enrique, AU - Cabadés O'Callaghan,Adolfo, AU - Cebrián Doménech,Javier, AU - López Merino,Vicente, AU - Sanjuán Mañez,Rafael, AU - Echánove Errazti,Ildefonso, AU - Valencia Martín,José, AU - Bertomeu Martínez,Vicente, AU - ,, PY - 2004/1/30/pubmed PY - 2004/4/17/medline PY - 2004/1/30/entrez SP - 12 EP - 9 JF - Revista espanola de cardiologia JO - Rev Esp Cardiol VL - 57 IS - 1 N2 - INTRODUCTION AND OBJECTIVES: Some authors have described seasonal variations in the incidence of acute myocardial infarction. The aim of this study was to determine the existence of seasonal rhythms in admissions for acute myocardial infarction to coronary care units, and in mortality, and to analyze the influence of age on environmental factors. PATIENTS AND METHOD: The study included a total of 8400 consecutive patients with acute myocardial infarction admitted to 12 coronary care units in the PRIMVAC registry from January 1995 to December 1999. Seasonal rhythms were analyzed with the time series method and the Cosinor regression equation. The influence of age was analyzed with the chi 2 test. RESULTS: The total number of admissions increased in winter and decreased in summer. The highest peak (acrophase) occurred in winter, with 2183 cases (r2=0.91), specifically in February, with 742 cases (r2=0.66). The age of the patients conditioned seasonal variations (P=.006), and the influence was statistically significant for patients over 65 years of age. Changes in mortality with time did not reach statistical significance. CONCLUSIONS: A seasonal rhythm in admissions for acute myocardial infarction was found, with an increase in winter and a decrease in summer. Age conditioned the effect of environmental factors on acute myocardial infarction, and patients aged 65 years or older were more sensitive to mechanisms that led to increases in admissions in winter. SN - 0300-8932 UR - https://www.unboundmedicine.com/medline/citation/14746713/[Seasonal_variations_in_admissions_for_acute_myocardial_infarction__The_PRIMVAC_study]_ DB - PRIME DP - Unbound Medicine ER -