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Schistosomiasis control: keep taking the tablets.
Trends Parasitol. 2004 Feb; 20(2):92-7.TP

Abstract

Despite the limited reports of praziquantel resistance, the relative success of chemotherapy-based control programmes for schistosomiasis has prompted overdue efforts to expand the use of cheap, generic, praziquantel in sub-Saharan Africa. The likely impact of such programmes on the development and spread of praziquantel resistance is uncertain, but this possibility reinforces the need for monitoring the spectrum of praziquantel sensitivity of schistosome populations and for an improved knowledge of the precise targets for the action of the drug. The search for alternatives to praziquantel and other tools for control of schistosomiasis must continue.

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Authors+Show Affiliations

Hagan P
Division of Infection and Immunity, Institute of Biomedical and Life Sciences, Joseph Black Building (B4-09d), University of Glasgow, G12 8QQ, UK. p.hagan@bio.gla.ac.uk
Appleton CC
No affiliation info available
Coles GC
No affiliation info available
Kusel JR
No affiliation info available
Tchuem-Tchuenté LA
No affiliation info available

MeSH

Administration, OralAnimalsDrug ResistanceHumansParasitic Sensitivity TestsPraziquantelSchistosomaSchistosomiasisSchistosomicidesTablets

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

14747023

Citation

Hagan, Paul, et al. "Schistosomiasis Control: Keep Taking the Tablets." Trends in Parasitology, vol. 20, no. 2, 2004, pp. 92-7.
Hagan P, Appleton CC, Coles GC, et al. Schistosomiasis control: keep taking the tablets. Trends Parasitol. 2004;20(2):92-7.
Hagan, P., Appleton, C. C., Coles, G. C., Kusel, J. R., & Tchuem-Tchuenté, L. A. (2004). Schistosomiasis control: keep taking the tablets. Trends in Parasitology, 20(2), 92-7.
Hagan P, et al. Schistosomiasis Control: Keep Taking the Tablets. Trends Parasitol. 2004;20(2):92-7. PubMed PMID: 14747023.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Schistosomiasis control: keep taking the tablets. AU - Hagan,Paul, AU - Appleton,Christopher C, AU - Coles,Gerald C, AU - Kusel,John R, AU - Tchuem-Tchuenté,Louis Albert, PY - 2004/1/30/pubmed PY - 2004/7/30/medline PY - 2004/1/30/entrez SP - 92 EP - 7 JF - Trends in parasitology JO - Trends Parasitol VL - 20 IS - 2 N2 - Despite the limited reports of praziquantel resistance, the relative success of chemotherapy-based control programmes for schistosomiasis has prompted overdue efforts to expand the use of cheap, generic, praziquantel in sub-Saharan Africa. The likely impact of such programmes on the development and spread of praziquantel resistance is uncertain, but this possibility reinforces the need for monitoring the spectrum of praziquantel sensitivity of schistosome populations and for an improved knowledge of the precise targets for the action of the drug. The search for alternatives to praziquantel and other tools for control of schistosomiasis must continue. SN - 1471-4922 UR - https://www.unboundmedicine.com/medline/citation/14747023/Schistosomiasis_control:_keep_taking_the_tablets_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1471492203003222 DB - PRIME DP - Unbound Medicine ER -