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Subcapsular liver hematoma in HELLP syndrome: Evaluation of diagnostic and therapeutic options--a unicenter study.
Am J Obstet Gynecol. 2004 Jan; 190(1):106-12.AJ

Abstract

OBJECTIVE

Subcapsular liver hematoma formation has been reported in less than 2% of pregnancies complicated by HELLP (hemolysis, elevated liver enzymes, low platelets) syndrome. The purpose of this study was to identify the main diagnostic and therapeutic options for management of these patients.

STUDY DESIGN

In this 10-year retrospective review, we performed a computer-directed search of all cases of confirmed HELLP syndrome with hepatic hematoma treated in the surgical department of our tertiary care referral medical center.

RESULTS

Five patients with subcapsular liver hematoma in HELLP syndrome could be identified. All patients received transabdominal ultrasound, computed tomography, or magnetic resonance imaging. Conservative treatment was successful in three patients. Emergency surgical intervention was necessary in two patients, including one liver transplantation.

CONCLUSION

The case series shows the full diagnostic spectrum with transabdominal ultrasound, computed tomography, and magnetic resonance imaging, as well as the different therapeutic options varying from conservative therapy to operative management, including liver transplantation.

Authors+Show Affiliations

Department of General Surgery, University Hospital Tuebingen, Tuebingen, Germany. corinna.wicke@med.uni-tuebingen.deNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

14749644

Citation

Wicke, Corinna, et al. "Subcapsular Liver Hematoma in HELLP Syndrome: Evaluation of Diagnostic and Therapeutic Options--a Unicenter Study." American Journal of Obstetrics and Gynecology, vol. 190, no. 1, 2004, pp. 106-12.
Wicke C, Pereira PL, Neeser E, et al. Subcapsular liver hematoma in HELLP syndrome: Evaluation of diagnostic and therapeutic options--a unicenter study. Am J Obstet Gynecol. 2004;190(1):106-12.
Wicke, C., Pereira, P. L., Neeser, E., Flesch, I., Rodegerdts, E. A., & Becker, H. D. (2004). Subcapsular liver hematoma in HELLP syndrome: Evaluation of diagnostic and therapeutic options--a unicenter study. American Journal of Obstetrics and Gynecology, 190(1), 106-12.
Wicke C, et al. Subcapsular Liver Hematoma in HELLP Syndrome: Evaluation of Diagnostic and Therapeutic Options--a Unicenter Study. Am J Obstet Gynecol. 2004;190(1):106-12. PubMed PMID: 14749644.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Subcapsular liver hematoma in HELLP syndrome: Evaluation of diagnostic and therapeutic options--a unicenter study. AU - Wicke,Corinna, AU - Pereira,Philippe L, AU - Neeser,Eva, AU - Flesch,Ingo, AU - Rodegerdts,Enno A, AU - Becker,Horst Dieter, PY - 2004/1/30/pubmed PY - 2004/2/26/medline PY - 2004/1/30/entrez SP - 106 EP - 12 JF - American journal of obstetrics and gynecology JO - Am J Obstet Gynecol VL - 190 IS - 1 N2 - OBJECTIVE: Subcapsular liver hematoma formation has been reported in less than 2% of pregnancies complicated by HELLP (hemolysis, elevated liver enzymes, low platelets) syndrome. The purpose of this study was to identify the main diagnostic and therapeutic options for management of these patients. STUDY DESIGN: In this 10-year retrospective review, we performed a computer-directed search of all cases of confirmed HELLP syndrome with hepatic hematoma treated in the surgical department of our tertiary care referral medical center. RESULTS: Five patients with subcapsular liver hematoma in HELLP syndrome could be identified. All patients received transabdominal ultrasound, computed tomography, or magnetic resonance imaging. Conservative treatment was successful in three patients. Emergency surgical intervention was necessary in two patients, including one liver transplantation. CONCLUSION: The case series shows the full diagnostic spectrum with transabdominal ultrasound, computed tomography, and magnetic resonance imaging, as well as the different therapeutic options varying from conservative therapy to operative management, including liver transplantation. SN - 0002-9378 UR - https://www.unboundmedicine.com/medline/citation/14749644/Subcapsular_liver_hematoma_in_HELLP_syndrome:_Evaluation_of_diagnostic_and_therapeutic_options__a_unicenter_study_ DB - PRIME DP - Unbound Medicine ER -