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Prophylactic ciprofloxacin drops after tympanostomy tube insertion.
Saudi Med J 2004; 25(1):38-40SM

Abstract

OBJECTIVE

To evaluate the effectiveness of prophylactic ciprofloxacin drops in decreasing the incidence of post-tympanostomy otorrhea, and the relation between middle ear content and post-tympanostomy otorrhea.

METHODS

One hundred and fifty patients aged 3-14 years underwent tympanostomy and tube insertion at the Prince Rashid Ben Al-Hasan Hospital, Al-Husn, Jordan during the interval between February 2000 to January 2003. The patients were randomized into 3 groups: group 1 (control group) received no antibiotic drops, group 2 received a single dose of ciprofloxacin drops intraoperatively and group 3 received an intraoperative dose followed by 5-day postoperative course.

RESULTS

Application of topical ciprofloxacin after tympanostomy tube insertion was associated with a significantly lower incidence of early post-tympanostomy otorrhea. The rate of otorrhea for the control group was 16.5% and the treatment groups were (group 1) 8.4%, (group 2) 8.2% and p=0.011. A single dose of antibiotics was effective when patient's middle ears were dry or had serous effusions. For those whose ears had mucoid or purulent content a 5-day course was indicated.

CONCLUSION

Topical administration of a single dose of ototopical ciprofloxacin after surgery is an effective treatment for the prevention of early post-tympanostomy otorrhea, and a prolonged course (5 days) may be indicated for those whose ears had purulent or thick mucoid contents, and the content of middle ear are important in predicating postoperative otorrhea.

Authors+Show Affiliations

Department of Otolaryngology, Prince Rashid Ben Al-Husn Hospital, Jordan. nawasreh1@hotmail.comNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

14758376

Citation

Nawasreh, Omer, and Ibrahim A. Al-Wedyan. "Prophylactic Ciprofloxacin Drops After Tympanostomy Tube Insertion." Saudi Medical Journal, vol. 25, no. 1, 2004, pp. 38-40.
Nawasreh O, Al-Wedyan IA. Prophylactic ciprofloxacin drops after tympanostomy tube insertion. Saudi Med J. 2004;25(1):38-40.
Nawasreh, O., & Al-Wedyan, I. A. (2004). Prophylactic ciprofloxacin drops after tympanostomy tube insertion. Saudi Medical Journal, 25(1), pp. 38-40.
Nawasreh O, Al-Wedyan IA. Prophylactic Ciprofloxacin Drops After Tympanostomy Tube Insertion. Saudi Med J. 2004;25(1):38-40. PubMed PMID: 14758376.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prophylactic ciprofloxacin drops after tympanostomy tube insertion. AU - Nawasreh,Omer, AU - Al-Wedyan,Ibrahim A, PY - 2004/2/6/pubmed PY - 2004/10/6/medline PY - 2004/2/6/entrez SP - 38 EP - 40 JF - Saudi medical journal JO - Saudi Med J VL - 25 IS - 1 N2 - OBJECTIVE: To evaluate the effectiveness of prophylactic ciprofloxacin drops in decreasing the incidence of post-tympanostomy otorrhea, and the relation between middle ear content and post-tympanostomy otorrhea. METHODS: One hundred and fifty patients aged 3-14 years underwent tympanostomy and tube insertion at the Prince Rashid Ben Al-Hasan Hospital, Al-Husn, Jordan during the interval between February 2000 to January 2003. The patients were randomized into 3 groups: group 1 (control group) received no antibiotic drops, group 2 received a single dose of ciprofloxacin drops intraoperatively and group 3 received an intraoperative dose followed by 5-day postoperative course. RESULTS: Application of topical ciprofloxacin after tympanostomy tube insertion was associated with a significantly lower incidence of early post-tympanostomy otorrhea. The rate of otorrhea for the control group was 16.5% and the treatment groups were (group 1) 8.4%, (group 2) 8.2% and p=0.011. A single dose of antibiotics was effective when patient's middle ears were dry or had serous effusions. For those whose ears had mucoid or purulent content a 5-day course was indicated. CONCLUSION: Topical administration of a single dose of ototopical ciprofloxacin after surgery is an effective treatment for the prevention of early post-tympanostomy otorrhea, and a prolonged course (5 days) may be indicated for those whose ears had purulent or thick mucoid contents, and the content of middle ear are important in predicating postoperative otorrhea. SN - 0379-5284 UR - https://www.unboundmedicine.com/medline/citation/14758376/Prophylactic_ciprofloxacin_drops_after_tympanostomy_tube_insertion_ DB - PRIME DP - Unbound Medicine ER -