Enantioselective Friedel-Crafts reaction of indoles with arylidene malonates catalyzed by iPr-bisoxazoline-Cu(OTf)2.Chem Commun (Camb). 2004 Feb 21CC
Abstract
The cheap and simple (i)Pr-bisoxazoline-Cu(OTf)(2) proves to be an efficient catalyst in the asymmetric Friedel-Crafts reaction of indole with arylidene malonates. In (i)BuOH, the S-enantiomer was obtained in up to 97% ee, while the opposite enantiomer was obtained in up to 78% ee in CH(2)Cl(2) or TTCE.
Pub Type(s)
Journal Article
Language
eng
PubMed ID
14765244
Citation
Zhou, Jian, and Yong Tang. "Enantioselective Friedel-Crafts Reaction of Indoles With Arylidene Malonates Catalyzed By IPr-bisoxazoline-Cu(OTf)2." Chemical Communications (Cambridge, England), 2004, pp. 432-3.
Zhou J, Tang Y. Enantioselective Friedel-Crafts reaction of indoles with arylidene malonates catalyzed by iPr-bisoxazoline-Cu(OTf)2. Chem Commun (Camb). 2004.
Zhou, J., & Tang, Y. (2004). Enantioselective Friedel-Crafts reaction of indoles with arylidene malonates catalyzed by iPr-bisoxazoline-Cu(OTf)2. Chemical Communications (Cambridge, England), (4), 432-3.
Zhou J, Tang Y. Enantioselective Friedel-Crafts Reaction of Indoles With Arylidene Malonates Catalyzed By IPr-bisoxazoline-Cu(OTf)2. Chem Commun (Camb). 2004 Feb 21;(4)432-3. PubMed PMID: 14765244.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Enantioselective Friedel-Crafts reaction of indoles with arylidene malonates catalyzed by iPr-bisoxazoline-Cu(OTf)2.
AU - Zhou,Jian,
AU - Tang,Yong,
Y1 - 2004/01/19/
PY - 2004/2/7/pubmed
PY - 2004/2/7/medline
PY - 2004/2/7/entrez
SP - 432
EP - 3
JF - Chemical communications (Cambridge, England)
JO - Chem Commun (Camb)
IS - 4
N2 - The cheap and simple (i)Pr-bisoxazoline-Cu(OTf)(2) proves to be an efficient catalyst in the asymmetric Friedel-Crafts reaction of indole with arylidene malonates. In (i)BuOH, the S-enantiomer was obtained in up to 97% ee, while the opposite enantiomer was obtained in up to 78% ee in CH(2)Cl(2) or TTCE.
SN - 1359-7345
UR - https://www.unboundmedicine.com/medline/citation/14765244/Enantioselective_Friedel_Crafts_reaction_of_indoles_with_arylidene_malonates_catalyzed_by_iPr_bisoxazoline_Cu_OTf_2_
DB - PRIME
DP - Unbound Medicine
ER -
