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Geranyl N-dimethylallylanthranilate, a new compound from Esenbeckia yaaxhokob.
Planta Med. 2004 Jan; 70(1):85-6.PM

Abstract

Through a bioactivity-guided fractionation from the acetone extract of the leaves from Esenbeckia yaaxhokob geranyl N-dimethylallylanthranilate (1), the first natural N- and O-prenylated anthranilate, was isolated in addition of the known natural products caryophyllene beta-oxide, caryolane-5beta,9beta-diol, spathulenol (2), friedeline, friedelanol, decaprenol, flindersiamine (3) and beta-sitosterol. The antimicrobial activities of the extract, fractions and pure compounds were evaluated against two Gram (+) and four Gram (-) bacteria. Compounds 1 and 2 exhibited moderated antimicrobial activity against Staphyloccocus aureus, while 3 was active against S. aureus and Streptococcus faecalis.

Authors+Show Affiliations

Aguilar-Guadarrama AB
Centro de Investigaciones Químicas de la Universidad Autónoma del Estado de Morelos, Chamilpa, Cuernavaca, Mor., México.
Rios MY
No affiliation info available

MeSH

Anti-Infective AgentsGram-Negative BacteriaGram-Positive BacteriaHumansMedicine, TraditionalMexicoMicrobial Sensitivity TestsPhytotherapyPlant ExtractsPlant LeavesPlants, Medicinalortho-Aminobenzoates

Pub Type(s)

Journal Article

Language

eng

PubMed ID

14765303

Citation

Aguilar-Guadarrama, A Berenice, and María Yolanda Rios. "Geranyl N-dimethylallylanthranilate, a New Compound From Esenbeckia Yaaxhokob." Planta Medica, vol. 70, no. 1, 2004, pp. 85-6.
Aguilar-Guadarrama AB, Rios MY. Geranyl N-dimethylallylanthranilate, a new compound from Esenbeckia yaaxhokob. Planta Med. 2004;70(1):85-6.
Aguilar-Guadarrama, A. B., & Rios, M. Y. (2004). Geranyl N-dimethylallylanthranilate, a new compound from Esenbeckia yaaxhokob. Planta Medica, 70(1), 85-6.
Aguilar-Guadarrama AB, Rios MY. Geranyl N-dimethylallylanthranilate, a New Compound From Esenbeckia Yaaxhokob. Planta Med. 2004;70(1):85-6. PubMed PMID: 14765303.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Geranyl N-dimethylallylanthranilate, a new compound from Esenbeckia yaaxhokob. AU - Aguilar-Guadarrama,A Berenice, AU - Rios,María Yolanda, PY - 2004/2/7/pubmed PY - 2004/3/31/medline PY - 2004/2/7/entrez SP - 85 EP - 6 JF - Planta medica JO - Planta Med VL - 70 IS - 1 N2 - Through a bioactivity-guided fractionation from the acetone extract of the leaves from Esenbeckia yaaxhokob geranyl N-dimethylallylanthranilate (1), the first natural N- and O-prenylated anthranilate, was isolated in addition of the known natural products caryophyllene beta-oxide, caryolane-5beta,9beta-diol, spathulenol (2), friedeline, friedelanol, decaprenol, flindersiamine (3) and beta-sitosterol. The antimicrobial activities of the extract, fractions and pure compounds were evaluated against two Gram (+) and four Gram (-) bacteria. Compounds 1 and 2 exhibited moderated antimicrobial activity against Staphyloccocus aureus, while 3 was active against S. aureus and Streptococcus faecalis. SN - 0032-0943 UR - https://www.unboundmedicine.com/medline/citation/14765303/Geranyl_N_dimethylallylanthranilate_a_new_compound_from_Esenbeckia_yaaxhokob_ DB - PRIME DP - Unbound Medicine ER -