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Role of bacterial flora in the pathogenesis & management of atopic dermatitis.
Indian J Med Res. 1992 Sep; 95:234-8.IJ

Abstract

The carriage state of Staphylococcus aureus and its role in the pathogenesis and management of atopic dermatitis were evaluated in 50 patients, aged 3 months to 12 yr. An equal number of age and sex matched controls were also studied. The positivity of Staph.aureus in patients with atopic dermatitis was 50 per cent from eczematous skin, 34 per cent from anterior nares and 26 per cent from normal skin. In controls, the comparative figures were 14 per cent from anterior nares and 10 per cent from normal skin. After institution of oral erythromycin or cloxacillin therapy (according to sensitivity), the colony counts dropped to 18 per cent from eczematous skin, 14 per cent from anterior nares and 8 per cent from normal skin after one week and to zero after 3 wk. This was associated with significant clinical improvement. The results of this study suggest that Staph. aureus aggravates the eczematous process in patients with atopic dermatitis and antibiotics decrease the severity and are useful in long term prognosis of the disease.

Authors+Show Affiliations

Department of Dermatology, Postgraduate Institute of Medical Education & Research, Chandigarh.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

1478727

Citation

Dhar, S, et al. "Role of Bacterial Flora in the Pathogenesis & Management of Atopic Dermatitis." The Indian Journal of Medical Research, vol. 95, 1992, pp. 234-8.
Dhar S, Kanwar AJ, Kaur S, et al. Role of bacterial flora in the pathogenesis & management of atopic dermatitis. Indian J Med Res. 1992;95:234-8.
Dhar, S., Kanwar, A. J., Kaur, S., Sharma, P., & Ganguly, N. K. (1992). Role of bacterial flora in the pathogenesis & management of atopic dermatitis. The Indian Journal of Medical Research, 95, 234-8.
Dhar S, et al. Role of Bacterial Flora in the Pathogenesis & Management of Atopic Dermatitis. Indian J Med Res. 1992;95:234-8. PubMed PMID: 1478727.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Role of bacterial flora in the pathogenesis & management of atopic dermatitis. AU - Dhar,S, AU - Kanwar,A J, AU - Kaur,S, AU - Sharma,P, AU - Ganguly,N K, PY - 1992/9/1/pubmed PY - 1992/9/1/medline PY - 1992/9/1/entrez SP - 234 EP - 8 JF - The Indian journal of medical research JO - Indian J Med Res VL - 95 N2 - The carriage state of Staphylococcus aureus and its role in the pathogenesis and management of atopic dermatitis were evaluated in 50 patients, aged 3 months to 12 yr. An equal number of age and sex matched controls were also studied. The positivity of Staph.aureus in patients with atopic dermatitis was 50 per cent from eczematous skin, 34 per cent from anterior nares and 26 per cent from normal skin. In controls, the comparative figures were 14 per cent from anterior nares and 10 per cent from normal skin. After institution of oral erythromycin or cloxacillin therapy (according to sensitivity), the colony counts dropped to 18 per cent from eczematous skin, 14 per cent from anterior nares and 8 per cent from normal skin after one week and to zero after 3 wk. This was associated with significant clinical improvement. The results of this study suggest that Staph. aureus aggravates the eczematous process in patients with atopic dermatitis and antibiotics decrease the severity and are useful in long term prognosis of the disease. SN - 0971-5916 UR - https://www.unboundmedicine.com/medline/citation/1478727/Role_of_bacterial_flora_in_the_pathogenesis_&_management_of_atopic_dermatitis_ L2 - https://www.diseaseinfosearch.org/result/9652 DB - PRIME DP - Unbound Medicine ER -