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[Migraine and non-steroidal anti-inflammatory agents].
Pathol Biol (Paris) 1992; 40(4):397-405PB

Abstract

Controlled studies of nonsteroidal antiinflammatory drugs (NSAIDs) for the management of migraine attacks or for the prophylactic long-term treatment of migraine are reviewed herein. A large number of NSAIDs have been tested against a placebo or reference drug, including aspirin, indomethacin, mefenamic acid, tolfenamic acid, flufenamic acid, ibuprofen, flurbiprofen, fenoprofen, naproxen and sodium naproxen, diclofenac and lornoxicam. For the treatment of acute attacks, published studies found that the NSAIDs were significantly more effective than the placebo and at least as effective as the reference drugs. Adverse effects were absent or mild in this indication. Studies of NSAIDs as prophylactic treatment of migraine attacks are less numerous but also point to the value of this approach. However, long-term use of NSAIDs is associated with side-effects, mainly involving the gastrointestinal tract.

Authors+Show Affiliations

Service de Médecine Interne, Hôpital Rothschild, Paris, France.No affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
English Abstract
Journal Article
Randomized Controlled Trial
Review

Language

fre

PubMed ID

1495823

Citation

Pradalier, A, and D Vincent. "[Migraine and Non-steroidal Anti-inflammatory Agents]." Pathologie-biologie, vol. 40, no. 4, 1992, pp. 397-405.
Pradalier A, Vincent D. [Migraine and non-steroidal anti-inflammatory agents]. Pathol Biol. 1992;40(4):397-405.
Pradalier, A., & Vincent, D. (1992). [Migraine and non-steroidal anti-inflammatory agents]. Pathologie-biologie, 40(4), pp. 397-405.
Pradalier A, Vincent D. [Migraine and Non-steroidal Anti-inflammatory Agents]. Pathol Biol. 1992;40(4):397-405. PubMed PMID: 1495823.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Migraine and non-steroidal anti-inflammatory agents]. AU - Pradalier,A, AU - Vincent,D, PY - 1992/4/1/pubmed PY - 1992/4/1/medline PY - 1992/4/1/entrez SP - 397 EP - 405 JF - Pathologie-biologie JO - Pathol. Biol. VL - 40 IS - 4 N2 - Controlled studies of nonsteroidal antiinflammatory drugs (NSAIDs) for the management of migraine attacks or for the prophylactic long-term treatment of migraine are reviewed herein. A large number of NSAIDs have been tested against a placebo or reference drug, including aspirin, indomethacin, mefenamic acid, tolfenamic acid, flufenamic acid, ibuprofen, flurbiprofen, fenoprofen, naproxen and sodium naproxen, diclofenac and lornoxicam. For the treatment of acute attacks, published studies found that the NSAIDs were significantly more effective than the placebo and at least as effective as the reference drugs. Adverse effects were absent or mild in this indication. Studies of NSAIDs as prophylactic treatment of migraine attacks are less numerous but also point to the value of this approach. However, long-term use of NSAIDs is associated with side-effects, mainly involving the gastrointestinal tract. SN - 0369-8114 UR - https://www.unboundmedicine.com/medline/citation/1495823/[Migraine_and_non_steroidal_anti_inflammatory_agents]_ L2 - http://www.diseaseinfosearch.org/result/4811 DB - PRIME DP - Unbound Medicine ER -