Enantioselective aza-Henry reaction catalyzed by a bifunctional organocatalyst.Org Lett. 2004 Feb 19; 6(4):625-7.OL
Abstract
[reaction: see text] The aza-Henry reaction of imines with nitroalkanes was promoted by chiral thiourea with an N,N-dimethylamino group to give beta-nitroamines with good enantioselectivity. Various N-protected imines were examined as substrates. N-Phosphinoylimine gave the best result in terms of chemical yield and enantioselectivity (up to 91% yield, up to 76% ee).
Pub Type(s)
Journal Article
Language
eng
PubMed ID
14961639
Citation
Okino, Tomotaka, et al. "Enantioselective aza-Henry Reaction Catalyzed By a Bifunctional Organocatalyst." Organic Letters, vol. 6, no. 4, 2004, pp. 625-7.
Okino T, Nakamura S, Furukawa T, et al. Enantioselective aza-Henry reaction catalyzed by a bifunctional organocatalyst. Org Lett. 2004;6(4):625-7.
Okino, T., Nakamura, S., Furukawa, T., & Takemoto, Y. (2004). Enantioselective aza-Henry reaction catalyzed by a bifunctional organocatalyst. Organic Letters, 6(4), 625-7.
Okino T, et al. Enantioselective aza-Henry Reaction Catalyzed By a Bifunctional Organocatalyst. Org Lett. 2004 Feb 19;6(4):625-7. PubMed PMID: 14961639.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Enantioselective aza-Henry reaction catalyzed by a bifunctional organocatalyst.
AU - Okino,Tomotaka,
AU - Nakamura,Satoru,
AU - Furukawa,Tomihiro,
AU - Takemoto,Yoshiji,
PY - 2004/2/14/pubmed
PY - 2004/2/14/medline
PY - 2004/2/14/entrez
SP - 625
EP - 7
JF - Organic letters
JO - Org Lett
VL - 6
IS - 4
N2 - [reaction: see text] The aza-Henry reaction of imines with nitroalkanes was promoted by chiral thiourea with an N,N-dimethylamino group to give beta-nitroamines with good enantioselectivity. Various N-protected imines were examined as substrates. N-Phosphinoylimine gave the best result in terms of chemical yield and enantioselectivity (up to 91% yield, up to 76% ee).
SN - 1523-7060
UR - https://www.unboundmedicine.com/medline/citation/14961639/Enantioselective_aza_Henry_reaction_catalyzed_by_a_bifunctional_organocatalyst_
DB - PRIME
DP - Unbound Medicine
ER -
