Tags

Type your tag names separated by a space and hit enter

Energy expenditure, nutrition status, and body composition in children with cystic fibrosis.

Abstract

OBJECTIVE

Undernutrition is a frequent complication in patients with cystic fibrosis (CF). Elevated energy requirements have been found to be 4% to 33% higher than in controls in some studies. Whether or not this is caused by a primary defect or energy metabolism is still a matter of controversy. To this end, we assessed energy expenditure, nutrition status, and body composition of clinically stable CF outpatients.

METHODS

Fifteen clinically stable CF patients, ages 2 to 15 y, were paired with 15 healthy control children. Measurements consisted of anthropometry and body composition. Plasma tocopherol, retinol, and hair zinc content were measured. Resting energy expenditure was determined by indirect calorimetry. Physical activity and dietary intake were recorded by recall methods.

RESULTS

Two children were nutritionally at risk according to the weight/height index, eight were normal, three were overweight, and two were obese. Body composition was similar in both groups. Zinc, tocopherol, and retinol levels were low in three, two, and three patients, respectively. Resting energy expenditures were 4.7 MJ/d (1127 +/- 220 kcal/d) in CF children and 4.63 MJ/d (1108 +/- 191 kcal/d) in control children (P = not significant). Physical activity level was sedentary in 86.6% of CF patients; the rest had a light physical activity pattern. Energy intake represented 141% of the estimated daily energy expenditure.

CONCLUSIONS

Non-oxygen-dependent CF children, without acute respiratory infection, had resting energy expenditures comparable to those of matched controls. Total energy expenditure was similar to or slightly lower than that in healthy children. Dietary recommendations for CF patients need to be reassessed.

Links

  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Institute of Nutrition and Food Technology, University of Chile, Macul 5540, Santiago, Chile.

    , , , , ,

    Source

    MeSH

    Adolescent
    Anthropometry
    Basal Metabolism
    Body Composition
    Calorimetry, Indirect
    Case-Control Studies
    Child
    Child, Preschool
    Cystic Fibrosis
    Energy Intake
    Energy Metabolism
    Exercise
    Female
    Humans
    Male
    Mental Recall
    Micronutrients
    Nutritional Requirements
    Nutritional Status
    Tocopherols
    Vitamin A

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    14962683

    Citation

    Marín, Verónica B., et al. "Energy Expenditure, Nutrition Status, and Body Composition in Children With Cystic Fibrosis." Nutrition (Burbank, Los Angeles County, Calif.), vol. 20, no. 2, 2004, pp. 181-6.
    Marín VB, Velandia S, Hunter B, et al. Energy expenditure, nutrition status, and body composition in children with cystic fibrosis. Nutrition. 2004;20(2):181-6.
    Marín, V. B., Velandia, S., Hunter, B., Gattas, V., Fielbaum, O., Herrera, O., & Díaz, E. (2004). Energy expenditure, nutrition status, and body composition in children with cystic fibrosis. Nutrition (Burbank, Los Angeles County, Calif.), 20(2), pp. 181-6.
    Marín VB, et al. Energy Expenditure, Nutrition Status, and Body Composition in Children With Cystic Fibrosis. Nutrition. 2004;20(2):181-6. PubMed PMID: 14962683.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Energy expenditure, nutrition status, and body composition in children with cystic fibrosis. AU - Marín,Verónica B, AU - Velandia,Sylvia, AU - Hunter,Bessie, AU - Gattas,Vivien, AU - Fielbaum,Oscar, AU - Herrera,Oscar, AU - Díaz,Erik, PY - 2004/2/14/pubmed PY - 2004/8/25/medline PY - 2004/2/14/entrez SP - 181 EP - 6 JF - Nutrition (Burbank, Los Angeles County, Calif.) JO - Nutrition VL - 20 IS - 2 N2 - OBJECTIVE: Undernutrition is a frequent complication in patients with cystic fibrosis (CF). Elevated energy requirements have been found to be 4% to 33% higher than in controls in some studies. Whether or not this is caused by a primary defect or energy metabolism is still a matter of controversy. To this end, we assessed energy expenditure, nutrition status, and body composition of clinically stable CF outpatients. METHODS: Fifteen clinically stable CF patients, ages 2 to 15 y, were paired with 15 healthy control children. Measurements consisted of anthropometry and body composition. Plasma tocopherol, retinol, and hair zinc content were measured. Resting energy expenditure was determined by indirect calorimetry. Physical activity and dietary intake were recorded by recall methods. RESULTS: Two children were nutritionally at risk according to the weight/height index, eight were normal, three were overweight, and two were obese. Body composition was similar in both groups. Zinc, tocopherol, and retinol levels were low in three, two, and three patients, respectively. Resting energy expenditures were 4.7 MJ/d (1127 +/- 220 kcal/d) in CF children and 4.63 MJ/d (1108 +/- 191 kcal/d) in control children (P = not significant). Physical activity level was sedentary in 86.6% of CF patients; the rest had a light physical activity pattern. Energy intake represented 141% of the estimated daily energy expenditure. CONCLUSIONS: Non-oxygen-dependent CF children, without acute respiratory infection, had resting energy expenditures comparable to those of matched controls. Total energy expenditure was similar to or slightly lower than that in healthy children. Dietary recommendations for CF patients need to be reassessed. SN - 0899-9007 UR - https://www.unboundmedicine.com/medline/citation/14962683/Energy_expenditure_nutrition_status_and_body_composition_in_children_with_cystic_fibrosis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0899900703002582 DB - PRIME DP - Unbound Medicine ER -