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Recurrent interface infiltration with hypopyon after astigmatic laser in situ keratomileusis on a penetrating corneal graft.
J Cataract Refract Surg. 2004 Jan; 30(1):257-8.JC

Abstract

A 56-year-old woman was referred with recurrent interface infiltration and hypopyon after astigmatic laser in situ keratomileusis (LASIK) on a corneal graft. Pseudomonas aeruginosa was isolated as the causative pathogen. Penetrating keratoplasty had been performed 2 years before refractive surgery. After the antibiotic medication was tapered, 3 recurrences of interface infiltration with hypopyon were observed. Penetrating rekeratoplasty was deemed appropriate. Histological examination of the explanted corneal graft revealed anterior stromal neutrophil infiltration. This case illustrates that microbial pathogens brought underneath the flap by LASIK can persist months later despite antimicrobial treatment.

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Authors+Show Affiliations

Reinhard T
Eye Hospital, Albert-Ludwig's University, Freiburg, Germany. reinhard@aug.uki.uni-freiburg.de
Knorz M
No affiliation info available
Sundmacher R
No affiliation info available

MeSH

Anti-Bacterial AgentsAstigmatismCorneaDrug Therapy, CombinationEye Infections, BacterialFemaleHumansKeratitisKeratomileusis, Laser In SituKeratoplasty, PenetratingMiddle AgedPseudomonas InfectionsPseudomonas aeruginosaRecurrenceReoperationSuppurationSurgical Wound Infection

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

14967300

Citation

Reinhard, Thomas, et al. "Recurrent Interface Infiltration With Hypopyon After Astigmatic Laser in Situ Keratomileusis On a Penetrating Corneal Graft." Journal of Cataract and Refractive Surgery, vol. 30, no. 1, 2004, pp. 257-8.
Reinhard T, Knorz M, Sundmacher R. Recurrent interface infiltration with hypopyon after astigmatic laser in situ keratomileusis on a penetrating corneal graft. J Cataract Refract Surg. 2004;30(1):257-8.
Reinhard, T., Knorz, M., & Sundmacher, R. (2004). Recurrent interface infiltration with hypopyon after astigmatic laser in situ keratomileusis on a penetrating corneal graft. Journal of Cataract and Refractive Surgery, 30(1), 257-8.
Reinhard T, Knorz M, Sundmacher R. Recurrent Interface Infiltration With Hypopyon After Astigmatic Laser in Situ Keratomileusis On a Penetrating Corneal Graft. J Cataract Refract Surg. 2004;30(1):257-8. PubMed PMID: 14967300.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Recurrent interface infiltration with hypopyon after astigmatic laser in situ keratomileusis on a penetrating corneal graft. AU - Reinhard,Thomas, AU - Knorz,Michael, AU - Sundmacher,Rainer, PY - 2003/05/29/accepted PY - 2004/2/18/pubmed PY - 2004/3/9/medline PY - 2004/2/18/entrez SP - 257 EP - 8 JF - Journal of cataract and refractive surgery JO - J Cataract Refract Surg VL - 30 IS - 1 N2 - A 56-year-old woman was referred with recurrent interface infiltration and hypopyon after astigmatic laser in situ keratomileusis (LASIK) on a corneal graft. Pseudomonas aeruginosa was isolated as the causative pathogen. Penetrating keratoplasty had been performed 2 years before refractive surgery. After the antibiotic medication was tapered, 3 recurrences of interface infiltration with hypopyon were observed. Penetrating rekeratoplasty was deemed appropriate. Histological examination of the explanted corneal graft revealed anterior stromal neutrophil infiltration. This case illustrates that microbial pathogens brought underneath the flap by LASIK can persist months later despite antimicrobial treatment. SN - 0886-3350 UR - https://www.unboundmedicine.com/medline/citation/14967300/Recurrent_interface_infiltration_with_hypopyon_after_astigmatic_laser_in_situ_keratomileusis_on_a_penetrating_corneal_graft_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S088633500300717X DB - PRIME DP - Unbound Medicine ER -