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Do women with polycystic ovary syndrome have an increased risk of cardiovascular disease? Review of the evidence.
Minerva Ginecol. 2004 Feb; 56(1):27-39.MG

Abstract

Polycystic ovary syndrome (PCOS) is a reproductive endocrine disorder found in ~5% of the general population and is characterized by chronic anovulation, hyperandrogenism, and insulin resistance. Women with PCOS are at increased risk for the development of Type II diabetes and may represent a unique group of women at high risk for the development of coronary heart disease (CHD). More adverse CHD risk profiles of women with PCOS have been demonstrated in several studies, yet actual health outcome studies have been inconclusive as to whether this translates into increased rates of cardiovascular disease in PCOS cases when compared to controls. This review focuses on the controversy surrounding the potential relationship between cardiovascular disease outcomes and polycystic ovary syndrome.

Authors+Show Affiliations

Talbott EO
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA. eot1@pitt.edu
Zborowskii JV
No affiliation info available
Boudraux MY
No affiliation info available

MeSH

AdultAge FactorsAgedAngina PectorisBlood CoagulationBlood Coagulation FactorsBody Mass IndexBody WeightC-Reactive ProteinCardiovascular DiseasesCarotid Artery DiseasesCase-Control StudiesCoronary DiseaseData Interpretation, StatisticalDiabetes Mellitus, Type 2FemaleFollow-Up StudiesHemodynamicsHumansHypertensionLinear ModelsMiddle AgedObesityPolycystic Ovary SyndromePrevalenceRisk FactorsTime Factors

Pub Type(s)

Comparative Study
Journal Article
Research Support, U.S. Gov't, P.H.S.
Review

Language

eng

PubMed ID

14973408

Clinical Trial Links

Risk of Coronary Heart Disease in Women With Polycystic Ovary Syndrome

Citation

Talbott, E O., et al. "Do Women With Polycystic Ovary Syndrome Have an Increased Risk of Cardiovascular Disease? Review of the Evidence." Minerva Ginecologica, vol. 56, no. 1, 2004, pp. 27-39.
Talbott EO, Zborowskii JV, Boudraux MY. Do women with polycystic ovary syndrome have an increased risk of cardiovascular disease? Review of the evidence. Minerva Ginecol. 2004;56(1):27-39.
Talbott, E. O., Zborowskii, J. V., & Boudraux, M. Y. (2004). Do women with polycystic ovary syndrome have an increased risk of cardiovascular disease? Review of the evidence. Minerva Ginecologica, 56(1), 27-39.
Talbott EO, Zborowskii JV, Boudraux MY. Do Women With Polycystic Ovary Syndrome Have an Increased Risk of Cardiovascular Disease? Review of the Evidence. Minerva Ginecol. 2004;56(1):27-39. PubMed PMID: 14973408.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Do women with polycystic ovary syndrome have an increased risk of cardiovascular disease? Review of the evidence. AU - Talbott,E O, AU - Zborowskii,J V, AU - Boudraux,M Y, PY - 2004/2/20/pubmed PY - 2004/5/1/medline PY - 2004/2/20/entrez SP - 27 EP - 39 JF - Minerva ginecologica JO - Minerva Ginecol VL - 56 IS - 1 N2 - Polycystic ovary syndrome (PCOS) is a reproductive endocrine disorder found in ~5% of the general population and is characterized by chronic anovulation, hyperandrogenism, and insulin resistance. Women with PCOS are at increased risk for the development of Type II diabetes and may represent a unique group of women at high risk for the development of coronary heart disease (CHD). More adverse CHD risk profiles of women with PCOS have been demonstrated in several studies, yet actual health outcome studies have been inconclusive as to whether this translates into increased rates of cardiovascular disease in PCOS cases when compared to controls. This review focuses on the controversy surrounding the potential relationship between cardiovascular disease outcomes and polycystic ovary syndrome. SN - 0026-4784 UR - https://www.unboundmedicine.com/medline/citation/14973408/Do_women_with_polycystic_ovary_syndrome_have_an_increased_risk_of_cardiovascular_disease_Review_of_the_evidence_ DB - PRIME DP - Unbound Medicine ER -