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A weight reduction program preserves fat-free mass but not metabolic rate in obese adolescents.
Obes Res 2004; 12(2):233-40OR

Abstract

OBJECTIVE

To determine the effects of a multidisciplinary weight reduction program on body composition and energy expenditure (EE) in severely obese adolescents.

RESEARCH METHODS AND PROCEDURES

Twenty-six severely obese adolescents, 12 to 16 years old [mean BMI: 33.9 kg/m(2); 41.5% fat mass (FM)] followed a 9-month weight reduction program including moderate energy restriction and progressive endurance and resistance training. Body composition was assessed by DXA, basal metabolic rate by indirect calorimetry, and EE by whole-body indirect calorimetry with the same activity program over 36-hour periods before starting and 9 months after the weight reduction period.

RESULTS

Adolescents gained (least-square mean +/- SE) 2.9 +/- 0.2 cm in height, lost 16.9 +/- 1.3 kg body weight (BW), 15.2 +/- 0.9 kg FM, and 1.8 +/- 0.5 kg fat-free mass (FFM) (p < 0.001). Basal metabolic rate, sleeping, sedentary, and daily EE were 8% to 14% lower 9 months after starting (p < 0.001) and still 6% to 12% lower after adjustment for FFM (p < 0.05). Energy cost of walking decreased by 22% (p < 0.001). The reduction in heart rate during sleep and sedentary activities (-10 to -13 beats/min), and walking (-20 to -25 beats/min) (p < 0.001) resulted from both the decrease in BW and physical training.

DISCUSSION

A weight reduction program combining moderate energy restriction and physical training in severely obese adolescents resulted in great BW and FM losses and improvement of cardiovascular fitness but did not prevent the decline in EE even after adjustment for FFM.

Authors+Show Affiliations

Protein-Energy Metabolism Research Unit, Institut National de la Recherche Agronomique, University of Auvergne, Clermont- Ferrand, France.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

14981215

Citation

Lazzer, Stefano, et al. "A Weight Reduction Program Preserves Fat-free Mass but Not Metabolic Rate in Obese Adolescents." Obesity Research, vol. 12, no. 2, 2004, pp. 233-40.
Lazzer S, Boirie Y, Montaurier C, et al. A weight reduction program preserves fat-free mass but not metabolic rate in obese adolescents. Obes Res. 2004;12(2):233-40.
Lazzer, S., Boirie, Y., Montaurier, C., Vernet, J., Meyer, M., & Vermorel, M. (2004). A weight reduction program preserves fat-free mass but not metabolic rate in obese adolescents. Obesity Research, 12(2), pp. 233-40.
Lazzer S, et al. A Weight Reduction Program Preserves Fat-free Mass but Not Metabolic Rate in Obese Adolescents. Obes Res. 2004;12(2):233-40. PubMed PMID: 14981215.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A weight reduction program preserves fat-free mass but not metabolic rate in obese adolescents. AU - Lazzer,Stefano, AU - Boirie,Yves, AU - Montaurier,Christophe, AU - Vernet,Jean, AU - Meyer,Martine, AU - Vermorel,Michel, PY - 2004/2/26/pubmed PY - 2004/10/8/medline PY - 2004/2/26/entrez SP - 233 EP - 40 JF - Obesity research JO - Obes. Res. VL - 12 IS - 2 N2 - OBJECTIVE: To determine the effects of a multidisciplinary weight reduction program on body composition and energy expenditure (EE) in severely obese adolescents. RESEARCH METHODS AND PROCEDURES: Twenty-six severely obese adolescents, 12 to 16 years old [mean BMI: 33.9 kg/m(2); 41.5% fat mass (FM)] followed a 9-month weight reduction program including moderate energy restriction and progressive endurance and resistance training. Body composition was assessed by DXA, basal metabolic rate by indirect calorimetry, and EE by whole-body indirect calorimetry with the same activity program over 36-hour periods before starting and 9 months after the weight reduction period. RESULTS: Adolescents gained (least-square mean +/- SE) 2.9 +/- 0.2 cm in height, lost 16.9 +/- 1.3 kg body weight (BW), 15.2 +/- 0.9 kg FM, and 1.8 +/- 0.5 kg fat-free mass (FFM) (p < 0.001). Basal metabolic rate, sleeping, sedentary, and daily EE were 8% to 14% lower 9 months after starting (p < 0.001) and still 6% to 12% lower after adjustment for FFM (p < 0.05). Energy cost of walking decreased by 22% (p < 0.001). The reduction in heart rate during sleep and sedentary activities (-10 to -13 beats/min), and walking (-20 to -25 beats/min) (p < 0.001) resulted from both the decrease in BW and physical training. DISCUSSION: A weight reduction program combining moderate energy restriction and physical training in severely obese adolescents resulted in great BW and FM losses and improvement of cardiovascular fitness but did not prevent the decline in EE even after adjustment for FFM. SN - 1071-7323 UR - https://www.unboundmedicine.com/medline/citation/14981215/A_weight_reduction_program_preserves_fat_free_mass_but_not_metabolic_rate_in_obese_adolescents_ L2 - https://doi.org/10.1038/oby.2004.30 DB - PRIME DP - Unbound Medicine ER -