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Gender influence on plasma triacylglycerol response to meals with different monounsaturated and saturated fatty acid content.
Eur J Clin Nutr 2004; 58(3):495-502EJ

Abstract

OBJECTIVE

Both gender and meal fatty acid composition modulate postprandial triacylglycerol (TAG) metabolism, but little information exists on their interaction. We compared postprandial TAG concentrations in men and women after test meals differing in the proportion of monounsaturated (MUFA) and saturated fatty acids (SFA).

SUBJECTS

Nine men (body mass index, BMI: 24.5+/-2.3 kg/m(2)) (mean+/-s.d.) and 10 premenopausal women (BMI: 21.2+/-1.7 kg/m(2)), young and healthy, habituated to a relatively high MUFA diet.

DESIGN

Plasma responses were studied after subjects consumed two meals, each providing 60 g of fat and 4.7 MJ, on different occasions: one meal was rich in MUFA (MUFA meal: 40 g MUFA; 12 g SFA) and the other meal was rich in SFA (SFA meal: 20 g MUFA; 32 g SFA). The total body and abdominal fat mass were assessed by dual energy X-ray absorptiometry.

RESULTS

Fasting plasma TAG concentration did not differ between meals or genders. No gender differences were observed in either total body or abdominal fat mass. The area under the plasma concentration vs time curve was on average 60% higher (P<0.001) in men than women. Repeated measures ANOVA showed a significant effect of meal x time interaction in men (P<0.001) but not in women (P=0.84). In men, maximal plasma TAG occurred at 4 h and was significantly greater after the MUFA meal (2.10+/-0.20 mmol/l) (mean+/-s.e.m.) than after the SFA meal (1.66+/-0.19 mmol/l) (P=0.01). TAG concentration at 5 h was also significantly greater after the MUFA meal. In women, the patterns of TAG responses were identical after the MUFA and SFA meals.

CONCLUSIONS

This study provides evidence that gender influences postprandial TAG concentrations when meal fatty acid composition is altered.

Authors+Show Affiliations

Laboratory of Nutrition and Clinical Dietetics, Department of Nutrition and Dietetics, Harokopio University, Athens, Greece. ckoutsari@hua.grNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

14985689

Citation

Koutsari, C, et al. "Gender Influence On Plasma Triacylglycerol Response to Meals With Different Monounsaturated and Saturated Fatty Acid Content." European Journal of Clinical Nutrition, vol. 58, no. 3, 2004, pp. 495-502.
Koutsari C, Zagana A, Tzoras I, et al. Gender influence on plasma triacylglycerol response to meals with different monounsaturated and saturated fatty acid content. Eur J Clin Nutr. 2004;58(3):495-502.
Koutsari, C., Zagana, A., Tzoras, I., Sidossis, L. S., & Matalas, A. L. (2004). Gender influence on plasma triacylglycerol response to meals with different monounsaturated and saturated fatty acid content. European Journal of Clinical Nutrition, 58(3), pp. 495-502.
Koutsari C, et al. Gender Influence On Plasma Triacylglycerol Response to Meals With Different Monounsaturated and Saturated Fatty Acid Content. Eur J Clin Nutr. 2004;58(3):495-502. PubMed PMID: 14985689.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Gender influence on plasma triacylglycerol response to meals with different monounsaturated and saturated fatty acid content. AU - Koutsari,C, AU - Zagana,A, AU - Tzoras,I, AU - Sidossis,L S, AU - Matalas,A L, PY - 2004/2/27/pubmed PY - 2004/6/30/medline PY - 2004/2/27/entrez SP - 495 EP - 502 JF - European journal of clinical nutrition JO - Eur J Clin Nutr VL - 58 IS - 3 N2 - OBJECTIVE: Both gender and meal fatty acid composition modulate postprandial triacylglycerol (TAG) metabolism, but little information exists on their interaction. We compared postprandial TAG concentrations in men and women after test meals differing in the proportion of monounsaturated (MUFA) and saturated fatty acids (SFA). SUBJECTS: Nine men (body mass index, BMI: 24.5+/-2.3 kg/m(2)) (mean+/-s.d.) and 10 premenopausal women (BMI: 21.2+/-1.7 kg/m(2)), young and healthy, habituated to a relatively high MUFA diet. DESIGN: Plasma responses were studied after subjects consumed two meals, each providing 60 g of fat and 4.7 MJ, on different occasions: one meal was rich in MUFA (MUFA meal: 40 g MUFA; 12 g SFA) and the other meal was rich in SFA (SFA meal: 20 g MUFA; 32 g SFA). The total body and abdominal fat mass were assessed by dual energy X-ray absorptiometry. RESULTS: Fasting plasma TAG concentration did not differ between meals or genders. No gender differences were observed in either total body or abdominal fat mass. The area under the plasma concentration vs time curve was on average 60% higher (P<0.001) in men than women. Repeated measures ANOVA showed a significant effect of meal x time interaction in men (P<0.001) but not in women (P=0.84). In men, maximal plasma TAG occurred at 4 h and was significantly greater after the MUFA meal (2.10+/-0.20 mmol/l) (mean+/-s.e.m.) than after the SFA meal (1.66+/-0.19 mmol/l) (P=0.01). TAG concentration at 5 h was also significantly greater after the MUFA meal. In women, the patterns of TAG responses were identical after the MUFA and SFA meals. CONCLUSIONS: This study provides evidence that gender influences postprandial TAG concentrations when meal fatty acid composition is altered. SN - 0954-3007 UR - https://www.unboundmedicine.com/medline/citation/14985689/Gender_influence_on_plasma_triacylglycerol_response_to_meals_with_different_monounsaturated_and_saturated_fatty_acid_content_ L2 - http://dx.doi.org/10.1038/sj.ejcn.1601836 DB - PRIME DP - Unbound Medicine ER -