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Beneficial effect of low-glycemic index diet in overweight NIDDM subjects.
Diabetes Care 1992; 15(4):562-4DC

Abstract

OBJECTIVE

To determine whether low-glycemic index (GI) diets have clinical utility in overweight patients with non-insulin-dependent diabetes mellitus (NIDDM).

RESEARCH DESIGN AND METHODS

Six patients with NIDDM were studied on both high- and low-GI diets of 6-wk duration with metabolic diets with a randomized crossover design. Both diets were of similar composition (57% carbohydrate, 23% fat, and 34 g/day dietary fiber), but the low-GI diet had a GI of 58 compared with 86 for the high-GI diet.

RESULTS

Small and similar amounts of weight were lost on both diets: 2.5 kg on high-GI diet and 1.8 kg on low-GI diet. On the low-GI diet, the mean level of serum fructosamine, as an index of overall blood glucose control, was lower than on the high-GI diet by 8% (P less than 0.05), and total serum cholesterol was lower by 7% (P less than 0.01).

CONCLUSIONS

In overweight patients with NIDDM, reducing diet GI improves overall blood glucose and lipid control.

Authors+Show Affiliations

Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Ontario, Canada.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

1499480

Citation

Wolever, T M., et al. "Beneficial Effect of Low-glycemic Index Diet in Overweight NIDDM Subjects." Diabetes Care, vol. 15, no. 4, 1992, pp. 562-4.
Wolever TM, Jenkins DJ, Vuksan V, et al. Beneficial effect of low-glycemic index diet in overweight NIDDM subjects. Diabetes Care. 1992;15(4):562-4.
Wolever, T. M., Jenkins, D. J., Vuksan, V., Jenkins, A. L., Wong, G. S., & Josse, R. G. (1992). Beneficial effect of low-glycemic index diet in overweight NIDDM subjects. Diabetes Care, 15(4), pp. 562-4.
Wolever TM, et al. Beneficial Effect of Low-glycemic Index Diet in Overweight NIDDM Subjects. Diabetes Care. 1992;15(4):562-4. PubMed PMID: 1499480.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Beneficial effect of low-glycemic index diet in overweight NIDDM subjects. AU - Wolever,T M, AU - Jenkins,D J, AU - Vuksan,V, AU - Jenkins,A L, AU - Wong,G S, AU - Josse,R G, PY - 1992/4/1/pubmed PY - 1992/4/1/medline PY - 1992/4/1/entrez SP - 562 EP - 4 JF - Diabetes care JO - Diabetes Care VL - 15 IS - 4 N2 - OBJECTIVE: To determine whether low-glycemic index (GI) diets have clinical utility in overweight patients with non-insulin-dependent diabetes mellitus (NIDDM). RESEARCH DESIGN AND METHODS: Six patients with NIDDM were studied on both high- and low-GI diets of 6-wk duration with metabolic diets with a randomized crossover design. Both diets were of similar composition (57% carbohydrate, 23% fat, and 34 g/day dietary fiber), but the low-GI diet had a GI of 58 compared with 86 for the high-GI diet. RESULTS: Small and similar amounts of weight were lost on both diets: 2.5 kg on high-GI diet and 1.8 kg on low-GI diet. On the low-GI diet, the mean level of serum fructosamine, as an index of overall blood glucose control, was lower than on the high-GI diet by 8% (P less than 0.05), and total serum cholesterol was lower by 7% (P less than 0.01). CONCLUSIONS: In overweight patients with NIDDM, reducing diet GI improves overall blood glucose and lipid control. SN - 0149-5992 UR - https://www.unboundmedicine.com/medline/citation/1499480/Beneficial_effect_of_low_glycemic_index_diet_in_overweight_NIDDM_subjects_ L2 - https://medlineplus.gov/obesity.html DB - PRIME DP - Unbound Medicine ER -