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In vitro antimicrobial and antioxidant activities of the essential oils and various extracts of Thymus eigii M. Zohary et P.H. Davis.
J Agric Food Chem. 2004 Mar 10; 52(5):1132-7.JA

Abstract

This study was designed to examine the in vitro antimicrobial and antioxidant activities of the essential oil and various extracts obtained from aerial parts of Thymus eigii. The essential oil was particularly found to possess stronger antimicrobial activity, whereas other nonpolar extracts and subfractions showed moderate activity and polar extracts remained almost inactive. GC-MS analysis of the oil resulted in the identification of 39 compounds, representing 93.7% of the oil; thymol (30.6%), carvacrol (26.1%), and p-cymene (13.0%) were the main components. The samples were also subjected to a screening for their possible antioxidant activity by using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and beta-carotene-linoleic acid assays. In the former case, the polar subfraction of the methanol extract was found to be superior to all extracts tested, only 16.8 microg/mL of which provided 50% inhibition, whereas all extracts, particularly the polar ones, seem to inhibit the oxidation of linoleic acid in the latter case. These data were further supported by total phenolics analysis, indicating that the antioxidative potential of the extracts was closely related to their phenolic constituents.

Authors+Show Affiliations

Tepe B
Department of Biology, Faculty of Science and Literature, Cumhuriyet University, Sivas, Turkey.
Daferera D
No affiliation info available
Sökmen M
No affiliation info available
Polissiou M
No affiliation info available
Sökmen A
No affiliation info available

MeSH

Anti-Bacterial AgentsAntioxidantsBiphenyl CompoundsCymenesGas Chromatography-Mass SpectrometryLamiaceaeLinoleic AcidMonoterpenesOils, VolatileOxidation-ReductionPicratesPlant ExtractsPlant OilsThymolbeta Carotene

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

14995110

Citation

Tepe, Bektaş, et al. "In Vitro Antimicrobial and Antioxidant Activities of the Essential Oils and Various Extracts of Thymus Eigii M. Zohary Et P.H. Davis." Journal of Agricultural and Food Chemistry, vol. 52, no. 5, 2004, pp. 1132-7.
Tepe B, Daferera D, Sökmen M, et al. In vitro antimicrobial and antioxidant activities of the essential oils and various extracts of Thymus eigii M. Zohary et P.H. Davis. J Agric Food Chem. 2004;52(5):1132-7.
Tepe, B., Daferera, D., Sökmen, M., Polissiou, M., & Sökmen, A. (2004). In vitro antimicrobial and antioxidant activities of the essential oils and various extracts of Thymus eigii M. Zohary et P.H. Davis. Journal of Agricultural and Food Chemistry, 52(5), 1132-7.
Tepe B, et al. In Vitro Antimicrobial and Antioxidant Activities of the Essential Oils and Various Extracts of Thymus Eigii M. Zohary Et P.H. Davis. J Agric Food Chem. 2004 Mar 10;52(5):1132-7. PubMed PMID: 14995110.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - In vitro antimicrobial and antioxidant activities of the essential oils and various extracts of Thymus eigii M. Zohary et P.H. Davis. AU - Tepe,Bektaş, AU - Daferera,Dimitra, AU - Sökmen,Münevver, AU - Polissiou,Moschos, AU - Sökmen,Atalay, PY - 2004/3/5/pubmed PY - 2004/5/5/medline PY - 2004/3/5/entrez SP - 1132 EP - 7 JF - Journal of agricultural and food chemistry JO - J Agric Food Chem VL - 52 IS - 5 N2 - This study was designed to examine the in vitro antimicrobial and antioxidant activities of the essential oil and various extracts obtained from aerial parts of Thymus eigii. The essential oil was particularly found to possess stronger antimicrobial activity, whereas other nonpolar extracts and subfractions showed moderate activity and polar extracts remained almost inactive. GC-MS analysis of the oil resulted in the identification of 39 compounds, representing 93.7% of the oil; thymol (30.6%), carvacrol (26.1%), and p-cymene (13.0%) were the main components. The samples were also subjected to a screening for their possible antioxidant activity by using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and beta-carotene-linoleic acid assays. In the former case, the polar subfraction of the methanol extract was found to be superior to all extracts tested, only 16.8 microg/mL of which provided 50% inhibition, whereas all extracts, particularly the polar ones, seem to inhibit the oxidation of linoleic acid in the latter case. These data were further supported by total phenolics analysis, indicating that the antioxidative potential of the extracts was closely related to their phenolic constituents. SN - 0021-8561 UR - https://www.unboundmedicine.com/medline/citation/14995110/In_vitro_antimicrobial_and_antioxidant_activities_of_the_essential_oils_and_various_extracts_of_Thymus_eigii_M__Zohary_et_P_H__Davis_ DB - PRIME DP - Unbound Medicine ER -