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Is ambulatory 24-h dual-probe pH monitoring useful in suspected ENT manifestations of GERD?
Dig Liver Dis. 2004 Feb; 36(2):105-10.DL

Abstract

BACKGROUND AND AIMS

The present study is aimed at assessing the relationship between ear, nose and throat manifestations and proximal reflux in gastro-oesophageal reflux disease by using 24-h dual-probe pH monitoring.

PATIENTS AND METHODS

Fifty-eight patients were included: (;) 28 patients with suspected ear, nose and throat manifestations of gastrooesophageal reflux disease: (ii) 18 patients with typical symptoms of gastro-oesophageal reflux disease without extraoesophageal manifestations of gastro-oesophageal reflux disease; (iii) 12 healthy volunteers. Ambulatory 24-h dual-probe pH monitoring was performed in all patients. Oesophagogastroscopy was performed in all patients of groups I and II. Ear, nose and throat examination was performed in all patients with ear, nose and throat complaints.

RESULTS

At the upper oesophageal sphincter, results of pH monitoring were significantly different between groups I and III (0.009 < P < 0.02) and between groups I and II (0.008 < P < 0.03). When comparing data at the lower oesophageal sphincter, we found a significant difference between groups II and III (0.002 < P < 0.009) and between groups I and III (0.001 < P < 0.002). Endoscopic examination of the oesophagus did not show any significant difference between groups I and II. Laryngoscopy was abnormal in 86% of the patients with ear, nose and throat symptoms.

CONCLUSIONS

Ambulatory 24-h dual-probe pH monitoring is useful in the assessment of patients with suspected ear, nose and throat manifestations of gastro-oesophageal reflux disease, especially in the case of abnormal laryngoscopy.

Authors+Show Affiliations

Department of Gastroenterology, AZ-VUB Academic Hospital, Laarbeeklaan 101, 1090 Brussels, Belgium. filip.sermon@az.vub.ac.beNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15002816

Citation

Sermon, F, et al. "Is Ambulatory 24-h Dual-probe pH Monitoring Useful in Suspected ENT Manifestations of GERD?" Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, vol. 36, no. 2, 2004, pp. 105-10.
Sermon F, Vanden Brande S, Roosens B, et al. Is ambulatory 24-h dual-probe pH monitoring useful in suspected ENT manifestations of GERD? Dig Liver Dis. 2004;36(2):105-10.
Sermon, F., Vanden Brande, S., Roosens, B., Mana, F., Deron, P., & Urbain, D. (2004). Is ambulatory 24-h dual-probe pH monitoring useful in suspected ENT manifestations of GERD? Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 36(2), 105-10.
Sermon F, et al. Is Ambulatory 24-h Dual-probe pH Monitoring Useful in Suspected ENT Manifestations of GERD. Dig Liver Dis. 2004;36(2):105-10. PubMed PMID: 15002816.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Is ambulatory 24-h dual-probe pH monitoring useful in suspected ENT manifestations of GERD? AU - Sermon,F, AU - Vanden Brande,S, AU - Roosens,B, AU - Mana,F, AU - Deron,P, AU - Urbain,D, PY - 2004/3/9/pubmed PY - 2004/5/12/medline PY - 2004/3/9/entrez SP - 105 EP - 10 JF - Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver JO - Dig Liver Dis VL - 36 IS - 2 N2 - BACKGROUND AND AIMS: The present study is aimed at assessing the relationship between ear, nose and throat manifestations and proximal reflux in gastro-oesophageal reflux disease by using 24-h dual-probe pH monitoring. PATIENTS AND METHODS: Fifty-eight patients were included: (;) 28 patients with suspected ear, nose and throat manifestations of gastrooesophageal reflux disease: (ii) 18 patients with typical symptoms of gastro-oesophageal reflux disease without extraoesophageal manifestations of gastro-oesophageal reflux disease; (iii) 12 healthy volunteers. Ambulatory 24-h dual-probe pH monitoring was performed in all patients. Oesophagogastroscopy was performed in all patients of groups I and II. Ear, nose and throat examination was performed in all patients with ear, nose and throat complaints. RESULTS: At the upper oesophageal sphincter, results of pH monitoring were significantly different between groups I and III (0.009 < P < 0.02) and between groups I and II (0.008 < P < 0.03). When comparing data at the lower oesophageal sphincter, we found a significant difference between groups II and III (0.002 < P < 0.009) and between groups I and III (0.001 < P < 0.002). Endoscopic examination of the oesophagus did not show any significant difference between groups I and II. Laryngoscopy was abnormal in 86% of the patients with ear, nose and throat symptoms. CONCLUSIONS: Ambulatory 24-h dual-probe pH monitoring is useful in the assessment of patients with suspected ear, nose and throat manifestations of gastro-oesophageal reflux disease, especially in the case of abnormal laryngoscopy. SN - 1590-8658 UR - https://www.unboundmedicine.com/medline/citation/15002816/Is_ambulatory_24_h_dual_probe_pH_monitoring_useful_in_suspected_ENT_manifestations_of_GERD L2 - https://linkinghub.elsevier.com/retrieve/pii/S1590-8658(03)00640-6 DB - PRIME DP - Unbound Medicine ER -