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Suppression of longitudinal increase in CSF F2-isoprostanes in Alzheimer's disease.
J Alzheimers Dis 2004; 6(1):93-7JA

Abstract

We report the first longitudinal analysis of cerebrospinal fluid (CSF) F2-isoprostanes (IsoPs), quantitative in vivo biomarkers of lipid peroxidation, in patients with mild Alzheimer's disease (AD). CSF F2-IsoPs (i) were significantly increased in patients followed over one year, (ii) correlated with some clinical indices of dementia following correction for variation in ventricular enlargement, and (iii) were significantly lower in patients who used both alpha-tocopherol and vitamin C.

Authors+Show Affiliations

Department Neurology, Oregon Health and Sciences University, Portland, OR, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

15004331

Citation

Quinn, Joseph F., et al. "Suppression of Longitudinal Increase in CSF F2-isoprostanes in Alzheimer's Disease." Journal of Alzheimer's Disease : JAD, vol. 6, no. 1, 2004, pp. 93-7.
Quinn JF, Montine KS, Moore M, et al. Suppression of longitudinal increase in CSF F2-isoprostanes in Alzheimer's disease. J Alzheimers Dis. 2004;6(1):93-7.
Quinn, J. F., Montine, K. S., Moore, M., Morrow, J. D., Kaye, J. A., & Montine, T. J. (2004). Suppression of longitudinal increase in CSF F2-isoprostanes in Alzheimer's disease. Journal of Alzheimer's Disease : JAD, 6(1), pp. 93-7.
Quinn JF, et al. Suppression of Longitudinal Increase in CSF F2-isoprostanes in Alzheimer's Disease. J Alzheimers Dis. 2004;6(1):93-7. PubMed PMID: 15004331.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Suppression of longitudinal increase in CSF F2-isoprostanes in Alzheimer's disease. AU - Quinn,Joseph F, AU - Montine,Kathleen S, AU - Moore,Milar, AU - Morrow,Jason D, AU - Kaye,Jeffrey A, AU - Montine,Thomas J, PY - 2004/3/9/pubmed PY - 2004/9/24/medline PY - 2004/3/9/entrez SP - 93 EP - 7 JF - Journal of Alzheimer's disease : JAD JO - J. Alzheimers Dis. VL - 6 IS - 1 N2 - We report the first longitudinal analysis of cerebrospinal fluid (CSF) F2-isoprostanes (IsoPs), quantitative in vivo biomarkers of lipid peroxidation, in patients with mild Alzheimer's disease (AD). CSF F2-IsoPs (i) were significantly increased in patients followed over one year, (ii) correlated with some clinical indices of dementia following correction for variation in ventricular enlargement, and (iii) were significantly lower in patients who used both alpha-tocopherol and vitamin C. SN - 1387-2877 UR - https://www.unboundmedicine.com/medline/citation/15004331/Suppression_of_longitudinal_increase_in_CSF_F2_isoprostanes_in_Alzheimer's_disease_ L2 - https://content.iospress.com/openurl?genre=article&issn=1387-2877&volume=6&issue=1&spage=93 DB - PRIME DP - Unbound Medicine ER -