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The prevalence of coeliac disease in Down's syndrome in Malta.
Ann Trop Paediatr 2004; 24(1):81-3AT

Abstract

The prevalence of coeliac disease is increased in individuals with Down's syndrome. The objective of this study was to assess the frequency of coeliac disease in Down's syndrome in Malta. One hundred children and adults with Down's were screened for coeliac disease. A history was taken from all of them and they were examined and measured for weight and height. A full blood count, antigliadin (IgG and IgA) and anti-endomysial antibodies were estimated. Equivocal cases were also screened for antireticulin antibodies. Jejunal biopsy was recommended in all serologically positive cases. The frequency of coeliac disease in Down's syndrome was 8%, much greater than that in the general population. Screening for coeliac disease in all cases of Down's syndrome is therefore recommended.

Authors+Show Affiliations

Paediatric Department, St Luke's Hospital, Guardamangia, Malta.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15005971

Citation

Sciberras, Chris, et al. "The Prevalence of Coeliac Disease in Down's Syndrome in Malta." Annals of Tropical Paediatrics, vol. 24, no. 1, 2004, pp. 81-3.
Sciberras C, Vella C, Grech V. The prevalence of coeliac disease in Down's syndrome in Malta. Ann Trop Paediatr. 2004;24(1):81-3.
Sciberras, C., Vella, C., & Grech, V. (2004). The prevalence of coeliac disease in Down's syndrome in Malta. Annals of Tropical Paediatrics, 24(1), pp. 81-3.
Sciberras C, Vella C, Grech V. The Prevalence of Coeliac Disease in Down's Syndrome in Malta. Ann Trop Paediatr. 2004;24(1):81-3. PubMed PMID: 15005971.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The prevalence of coeliac disease in Down's syndrome in Malta. AU - Sciberras,Chris, AU - Vella,Cecil, AU - Grech,Victor, PY - 2004/3/10/pubmed PY - 2004/6/23/medline PY - 2004/3/10/entrez SP - 81 EP - 3 JF - Annals of tropical paediatrics JO - Ann Trop Paediatr VL - 24 IS - 1 N2 - The prevalence of coeliac disease is increased in individuals with Down's syndrome. The objective of this study was to assess the frequency of coeliac disease in Down's syndrome in Malta. One hundred children and adults with Down's were screened for coeliac disease. A history was taken from all of them and they were examined and measured for weight and height. A full blood count, antigliadin (IgG and IgA) and anti-endomysial antibodies were estimated. Equivocal cases were also screened for antireticulin antibodies. Jejunal biopsy was recommended in all serologically positive cases. The frequency of coeliac disease in Down's syndrome was 8%, much greater than that in the general population. Screening for coeliac disease in all cases of Down's syndrome is therefore recommended. SN - 0272-4936 UR - https://www.unboundmedicine.com/medline/citation/15005971/The_prevalence_of_coeliac_disease_in_Down's_syndrome_in_Malta_ L2 - https://medlineplus.gov/downsyndrome.html DB - PRIME DP - Unbound Medicine ER -