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Microalbuminuria in type 2 diabetics: an important, overlooked cardiovascular risk factor.
J Clin Hypertens (Greenwich) 2004; 6(3):134-41; quiz 142-3JC

Abstract

The presence of microalbumin in the urine of persons with type 2 diabetes is perhaps the most important early signal heralding the onset of systemic vasculopathy and associated target organ damage to the brain, the heart, and the kidneys. It is easily measured and, unfortunately, frequently overlooked as a screening tool in clinical medicine. If present, it identifies patients at risk for early cardiovascular death and progressive renal disease. Microalbuminuria also identifies patients who need more rigorous cardiovascular risk management, especially more intensive blood pressure control, preferably below 130/80 mm Hg, and strict attention to glycemic control and lipid levels. Therapeutic strategies to facilitate better blood pressure control and reduce microalbuminuria likely will prove to be the most effective way to retard not only the progression of renal disease but also cardiovascular disease. Consequently, the identification and normalization of urine microalbumin excretion should be an important consideration in patients with diabetes.

Authors+Show Affiliations

Division of Nephrology, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201-1595, USA. mweir@medicine.umaryland.edu

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

15010646

Citation

Weir, Matthew R.. "Microalbuminuria in Type 2 Diabetics: an Important, Overlooked Cardiovascular Risk Factor." Journal of Clinical Hypertension (Greenwich, Conn.), vol. 6, no. 3, 2004, pp. 134-41; quiz 142-3.
Weir MR. Microalbuminuria in type 2 diabetics: an important, overlooked cardiovascular risk factor. J Clin Hypertens (Greenwich). 2004;6(3):134-41; quiz 142-3.
Weir, M. R. (2004). Microalbuminuria in type 2 diabetics: an important, overlooked cardiovascular risk factor. Journal of Clinical Hypertension (Greenwich, Conn.), 6(3), pp. 134-41; quiz 142-3.
Weir MR. Microalbuminuria in Type 2 Diabetics: an Important, Overlooked Cardiovascular Risk Factor. J Clin Hypertens (Greenwich). 2004;6(3):134-41; quiz 142-3. PubMed PMID: 15010646.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Microalbuminuria in type 2 diabetics: an important, overlooked cardiovascular risk factor. A1 - Weir,Matthew R, PY - 2004/3/11/pubmed PY - 2004/6/29/medline PY - 2004/3/11/entrez SP - 134-41; quiz 142-3 JF - Journal of clinical hypertension (Greenwich, Conn.) JO - J Clin Hypertens (Greenwich) VL - 6 IS - 3 N2 - The presence of microalbumin in the urine of persons with type 2 diabetes is perhaps the most important early signal heralding the onset of systemic vasculopathy and associated target organ damage to the brain, the heart, and the kidneys. It is easily measured and, unfortunately, frequently overlooked as a screening tool in clinical medicine. If present, it identifies patients at risk for early cardiovascular death and progressive renal disease. Microalbuminuria also identifies patients who need more rigorous cardiovascular risk management, especially more intensive blood pressure control, preferably below 130/80 mm Hg, and strict attention to glycemic control and lipid levels. Therapeutic strategies to facilitate better blood pressure control and reduce microalbuminuria likely will prove to be the most effective way to retard not only the progression of renal disease but also cardiovascular disease. Consequently, the identification and normalization of urine microalbumin excretion should be an important consideration in patients with diabetes. SN - 1524-6175 UR - https://www.unboundmedicine.com/medline/citation/15010646/Microalbuminuria_in_type_2_diabetics:_an_important_overlooked_cardiovascular_risk_factor_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=1524-6175&date=2004&volume=6&issue=3&spage=134 DB - PRIME DP - Unbound Medicine ER -