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[Hemorrhagic fever with renal syndrome: imported or native disease in the Zadar region].
Acta Med Croatica. 2003; 57(5):437-40.AM

Abstract

AIM

The aim of the study is to warn of the need of clinical hemorrhagic fever with renal syndrome (HFRS) recognition and determination, and of the risk of its spread from a new focus of this natural zoonosis near Zadar (north Dalmatia), i.e., in the northern part (Lika) of the Zadar County.

METHOD

Clinical and epidemiologic characteristics of HFRS were analyzed in four patients. Patient sera were analyzed for Puumala (PUU) and Hantaan (HTN) viruses by immunofluorescence test (IFT) and immunoenzyme test (ELISA).

RESULTS

Epidemiologic studies confirmed the source of infection to be out of the area in three patients, whereas in one patient it was near Zadar area. Mild symptoms pointed to the disease. Pathologic findings showed pathologic leukocyte values (leukocytosis), two- to four-fold alanine aminotransferase, aspartate aminotransferase and creatinine increase in serum, proteinuria and erythrocyturia. A significant PUU antibody titer was found by serum IF and ELISA.

CONCLUSION

The occurrence of HFRS in the Zadar area was confirmed by clinical description and laboratory evidence. The newly identified focus was in the vicinity of this area could imply a risk for the disease epidemic in the Zadar area.

Authors+Show Affiliations

Odjel za zarazne bolesti, Opća bolnica Zadar, Boze Pericića 5 23000 Zadar, Hrvatska. boris.dzelalija@zd.tel.hrNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

hrv

PubMed ID

15011474

Citation

Dzelalija, Boris, et al. "[Hemorrhagic Fever With Renal Syndrome: Imported or Native Disease in the Zadar Region]." Acta Medica Croatica : Casopis Hravatske Akademije Medicinskih Znanosti, vol. 57, no. 5, 2003, pp. 437-40.
Dzelalija B, Medić A, Avsic-Zupanc T. [Hemorrhagic fever with renal syndrome: imported or native disease in the Zadar region]. Acta Med Croatica. 2003;57(5):437-40.
Dzelalija, B., Medić, A., & Avsic-Zupanc, T. (2003). [Hemorrhagic fever with renal syndrome: imported or native disease in the Zadar region]. Acta Medica Croatica : Casopis Hravatske Akademije Medicinskih Znanosti, 57(5), 437-40.
Dzelalija B, Medić A, Avsic-Zupanc T. [Hemorrhagic Fever With Renal Syndrome: Imported or Native Disease in the Zadar Region]. Acta Med Croatica. 2003;57(5):437-40. PubMed PMID: 15011474.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Hemorrhagic fever with renal syndrome: imported or native disease in the Zadar region]. AU - Dzelalija,Boris, AU - Medić,Alan, AU - Avsic-Zupanc,Tatjana, PY - 2004/3/12/pubmed PY - 2004/4/2/medline PY - 2004/3/12/entrez SP - 437 EP - 40 JF - Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti JO - Acta Med Croatica VL - 57 IS - 5 N2 - AIM: The aim of the study is to warn of the need of clinical hemorrhagic fever with renal syndrome (HFRS) recognition and determination, and of the risk of its spread from a new focus of this natural zoonosis near Zadar (north Dalmatia), i.e., in the northern part (Lika) of the Zadar County. METHOD: Clinical and epidemiologic characteristics of HFRS were analyzed in four patients. Patient sera were analyzed for Puumala (PUU) and Hantaan (HTN) viruses by immunofluorescence test (IFT) and immunoenzyme test (ELISA). RESULTS: Epidemiologic studies confirmed the source of infection to be out of the area in three patients, whereas in one patient it was near Zadar area. Mild symptoms pointed to the disease. Pathologic findings showed pathologic leukocyte values (leukocytosis), two- to four-fold alanine aminotransferase, aspartate aminotransferase and creatinine increase in serum, proteinuria and erythrocyturia. A significant PUU antibody titer was found by serum IF and ELISA. CONCLUSION: The occurrence of HFRS in the Zadar area was confirmed by clinical description and laboratory evidence. The newly identified focus was in the vicinity of this area could imply a risk for the disease epidemic in the Zadar area. SN - 1330-0164 UR - https://www.unboundmedicine.com/medline/citation/15011474/[Hemorrhagic_fever_with_renal_syndrome:_imported_or_native_disease_in_the_Zadar_region]_ L2 - http://www.diseaseinfosearch.org/result/3317 DB - PRIME DP - Unbound Medicine ER -