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Antioxidant, antimicrobial, antiulcer and analgesic activities of nettle (Urtica dioica L.).
J Ethnopharmacol. 2004 Feb; 90(2-3):205-15.JE

Abstract

In this study, water extract of nettle (Urtica dioica L.) (WEN) was studied for antioxidant, antimicrobial, antiulcer and analgesic properties. The antioxidant properties of WEN were evaluated using different antioxidant tests, including reducing power, free radical scavenging, superoxide anion radical scavenging, hydrogen peroxide scavenging, and metal chelating activities. WEN had powerful antioxidant activity. The 50, 100 and 250 microg amounts of WEN showed 39, 66 and 98% inhibition on peroxidation of linoleic acid emulsion, respectively, while 60 microg/ml of alpha-tocopherol, exhibited only 30% inhibition. Moreover, WEN had effective reducing power, free radical scavenging, superoxide anion radical scavenging, hydrogen peroxide scavenging, and metal chelating activities at the same concentrations. Those various antioxidant activities were compared to standard antioxidants such as butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT), quercetin, and alpha-tocopherol. In addition, total phenolic compounds in the WEN were determined as pyrocatechol equivalent. WEN also showed antimicrobial activity against nine microorganisms, antiulcer activity against ethanol-induced ulcerogenesis and analgesic effect on acetic acid-induced stretching.

Authors+Show Affiliations

Gülçin I
Department of Chemistry, Faculty of Science and Arts, Atatürk University, 25240 Erzurum, Turkey.
Küfrevioglu OI
No affiliation info available
Oktay M
No affiliation info available
Büyükokuroglu ME
No affiliation info available

MeSH

Analgesics, Non-NarcoticAnimalsAnti-Infective AgentsAnti-Ulcer AgentsAntioxidantsFemaleMaleMicePain MeasurementPhytotherapyPlant Components, AerialPlant ExtractsRatsRats, Sprague-DawleyUrtica dioica

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15013182

Citation

Gülçin, Ilhami, et al. "Antioxidant, Antimicrobial, Antiulcer and Analgesic Activities of Nettle (Urtica Dioica L.)." Journal of Ethnopharmacology, vol. 90, no. 2-3, 2004, pp. 205-15.
Gülçin I, Küfrevioglu OI, Oktay M, et al. Antioxidant, antimicrobial, antiulcer and analgesic activities of nettle (Urtica dioica L.). J Ethnopharmacol. 2004;90(2-3):205-15.
Gülçin, I., Küfrevioglu, O. I., Oktay, M., & Büyükokuroglu, M. E. (2004). Antioxidant, antimicrobial, antiulcer and analgesic activities of nettle (Urtica dioica L.). Journal of Ethnopharmacology, 90(2-3), 205-15.
Gülçin I, et al. Antioxidant, Antimicrobial, Antiulcer and Analgesic Activities of Nettle (Urtica Dioica L.). J Ethnopharmacol. 2004;90(2-3):205-15. PubMed PMID: 15013182.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antioxidant, antimicrobial, antiulcer and analgesic activities of nettle (Urtica dioica L.). AU - Gülçin,Ilhami, AU - Küfrevioglu,O Irfan, AU - Oktay,Münir, AU - Büyükokuroglu,Mehmet Emin, PY - 2003/01/27/received PY - 2003/07/30/revised PY - 2003/09/22/accepted PY - 2004/3/12/pubmed PY - 2004/4/13/medline PY - 2004/3/12/entrez SP - 205 EP - 15 JF - Journal of ethnopharmacology JO - J Ethnopharmacol VL - 90 IS - 2-3 N2 - In this study, water extract of nettle (Urtica dioica L.) (WEN) was studied for antioxidant, antimicrobial, antiulcer and analgesic properties. The antioxidant properties of WEN were evaluated using different antioxidant tests, including reducing power, free radical scavenging, superoxide anion radical scavenging, hydrogen peroxide scavenging, and metal chelating activities. WEN had powerful antioxidant activity. The 50, 100 and 250 microg amounts of WEN showed 39, 66 and 98% inhibition on peroxidation of linoleic acid emulsion, respectively, while 60 microg/ml of alpha-tocopherol, exhibited only 30% inhibition. Moreover, WEN had effective reducing power, free radical scavenging, superoxide anion radical scavenging, hydrogen peroxide scavenging, and metal chelating activities at the same concentrations. Those various antioxidant activities were compared to standard antioxidants such as butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT), quercetin, and alpha-tocopherol. In addition, total phenolic compounds in the WEN were determined as pyrocatechol equivalent. WEN also showed antimicrobial activity against nine microorganisms, antiulcer activity against ethanol-induced ulcerogenesis and analgesic effect on acetic acid-induced stretching. SN - 0378-8741 UR - https://www.unboundmedicine.com/medline/citation/15013182/Antioxidant_antimicrobial_antiulcer_and_analgesic_activities_of_nettle__Urtica_dioica_L___ DB - PRIME DP - Unbound Medicine ER -