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Antidiabetic drugs of plant origin used in China: compositions, pharmacology, and hypoglycemic mechanisms.

Abstract

The paper reviewed compositions and pharmacological effects of eight antidiabetic herbal drugs that have been approved by health regulatory agency for commercial use in China. Investigators attributed the hypoglycemic effect of these products to their ability to restore the functions of pancreatic tissues and cause an increase in insulin output, to inhibit the intestinal absorption of glucose, or to the facilitation of metabolites in insulin-dependent processes. Treatment with herbal drugs has an effect on protecting beta cells and smoothing out fluctuations in glucose levels. The use of these naturally derived agents in conjunction with conventional drug treatments such as an chemical agent or insulin permits the use of lower doses of the drug and/or decreased frequency of administration which decreases the side effects most commonly observed.

Authors+Show Affiliations

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School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200030, China. weijia@mail.sjtu.edu.cn

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Source

MeSH

Animals
Astragalus Plant
Blood Glucose
Diabetes Mellitus
Drug Combinations
Drugs, Chinese Herbal
Humans
Hypoglycemic Agents
Insulin Resistance
Panax
Phytotherapy
Plants, Medicinal
Rehmannia

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

15015278

Citation

Jia, Wei, et al. "Antidiabetic Drugs of Plant Origin Used in China: Compositions, Pharmacology, and Hypoglycemic Mechanisms." Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, vol. 28, no. 2, 2003, pp. 108-13.
Jia W, Gao WY, Xiao PG. Antidiabetic drugs of plant origin used in China: compositions, pharmacology, and hypoglycemic mechanisms. Zhongguo Zhong Yao Za Zhi. 2003;28(2):108-13.
Jia, W., Gao, W. Y., & Xiao, P. G. (2003). Antidiabetic drugs of plant origin used in China: compositions, pharmacology, and hypoglycemic mechanisms. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, 28(2), pp. 108-13.
Jia W, Gao WY, Xiao PG. Antidiabetic Drugs of Plant Origin Used in China: Compositions, Pharmacology, and Hypoglycemic Mechanisms. Zhongguo Zhong Yao Za Zhi. 2003;28(2):108-13. PubMed PMID: 15015278.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antidiabetic drugs of plant origin used in China: compositions, pharmacology, and hypoglycemic mechanisms. AU - Jia,Wei, AU - Gao,Wen-yuan, AU - Xiao,Pei-gen, PY - 2004/3/16/pubmed PY - 2004/6/23/medline PY - 2004/3/16/entrez SP - 108 EP - 13 JF - Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica JO - Zhongguo Zhong Yao Za Zhi VL - 28 IS - 2 N2 - The paper reviewed compositions and pharmacological effects of eight antidiabetic herbal drugs that have been approved by health regulatory agency for commercial use in China. Investigators attributed the hypoglycemic effect of these products to their ability to restore the functions of pancreatic tissues and cause an increase in insulin output, to inhibit the intestinal absorption of glucose, or to the facilitation of metabolites in insulin-dependent processes. Treatment with herbal drugs has an effect on protecting beta cells and smoothing out fluctuations in glucose levels. The use of these naturally derived agents in conjunction with conventional drug treatments such as an chemical agent or insulin permits the use of lower doses of the drug and/or decreased frequency of administration which decreases the side effects most commonly observed. SN - 1001-5302 UR - https://www.unboundmedicine.com/medline/citation/15015278/Antidiabetic_drugs_of_plant_origin_used_in_China:_compositions_pharmacology_and_hypoglycemic_mechanisms_ L2 - https://medlineplus.gov/herbalmedicine.html DB - PRIME DP - Unbound Medicine ER -