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Is vitamin A consumption a risk factor for osteoporotic fracture?
Proc Nutr Soc. 2003 Nov; 62(4):845-50.PN

Abstract

Severe vitamin A toxicity is known to have adverse effects on skeletal health. Studies involving animal models and case reports have documented that hypervitaminosis A is associated with bone resorption, hypercalcaemia and bone abnormalities. More recently, some epidemiological studies have suggested that high habitual intake of vitamin A could contribute to low bone mineral content and fracture risk. The evidence relating to the possible deleterious role of vitamin A in bone health is of variable quality and is potentially confounded by collinearity of nutrient intake and difficulties in assessing vitamin A exposure. Furthermore, because intake of vitamin A varies between studies it is not possible to define an intake threshold associated with harm.

Authors+Show Affiliations

Human Nutrition Unit, Division of Clinical Sciences (North), University of Sheffield, Northern General Hospital, Herries Road, Sheffield 55 7AU, UK. m.e.barker@sheffield.ac.ukNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

15018484

Citation

Barker, Margo E., and Aubrey Blumsohn. "Is Vitamin a Consumption a Risk Factor for Osteoporotic Fracture?" The Proceedings of the Nutrition Society, vol. 62, no. 4, 2003, pp. 845-50.
Barker ME, Blumsohn A. Is vitamin A consumption a risk factor for osteoporotic fracture? Proc Nutr Soc. 2003;62(4):845-50.
Barker, M. E., & Blumsohn, A. (2003). Is vitamin A consumption a risk factor for osteoporotic fracture? The Proceedings of the Nutrition Society, 62(4), 845-50.
Barker ME, Blumsohn A. Is Vitamin a Consumption a Risk Factor for Osteoporotic Fracture. Proc Nutr Soc. 2003;62(4):845-50. PubMed PMID: 15018484.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Is vitamin A consumption a risk factor for osteoporotic fracture? AU - Barker,Margo E, AU - Blumsohn,Aubrey, PY - 2004/3/17/pubmed PY - 2004/7/23/medline PY - 2004/3/17/entrez SP - 845 EP - 50 JF - The Proceedings of the Nutrition Society JO - Proc Nutr Soc VL - 62 IS - 4 N2 - Severe vitamin A toxicity is known to have adverse effects on skeletal health. Studies involving animal models and case reports have documented that hypervitaminosis A is associated with bone resorption, hypercalcaemia and bone abnormalities. More recently, some epidemiological studies have suggested that high habitual intake of vitamin A could contribute to low bone mineral content and fracture risk. The evidence relating to the possible deleterious role of vitamin A in bone health is of variable quality and is potentially confounded by collinearity of nutrient intake and difficulties in assessing vitamin A exposure. Furthermore, because intake of vitamin A varies between studies it is not possible to define an intake threshold associated with harm. SN - 0029-6651 UR - https://www.unboundmedicine.com/medline/citation/15018484/Is_vitamin_A_consumption_a_risk_factor_for_osteoporotic_fracture L2 - https://www.cambridge.org/core/product/identifier/S0029665103001113/type/journal_article DB - PRIME DP - Unbound Medicine ER -