Tipping the balance toward longevity.Dev Cell. 2004 Mar; 6(3):315-6.DC
Abstract
Genetic experiments in C. elegans suggested that SIR2, an NAD-dependent protein deacetylase, acts through FOXO/DAF-16 transcription factor to prolong life. Recent studies show that mammalian SIR2 deacetylates FOXO, and may maximize survival by tempering cell death and increasing stress resistance.
Links
MeSH
Pub Type(s)
Journal Article
Language
eng
PubMed ID
15030753
Citation
Antebi, Adam. "Tipping the Balance Toward Longevity." Developmental Cell, vol. 6, no. 3, 2004, pp. 315-6.
Antebi A. Tipping the balance toward longevity. Dev Cell. 2004;6(3):315-6.
Antebi, A. (2004). Tipping the balance toward longevity. Developmental Cell, 6(3), 315-6.
Antebi A. Tipping the Balance Toward Longevity. Dev Cell. 2004;6(3):315-6. PubMed PMID: 15030753.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Tipping the balance toward longevity.
A1 - Antebi,Adam,
PY - 2004/3/20/pubmed
PY - 2004/4/28/medline
PY - 2004/3/20/entrez
SP - 315
EP - 6
JF - Developmental cell
JO - Dev Cell
VL - 6
IS - 3
N2 - Genetic experiments in C. elegans suggested that SIR2, an NAD-dependent protein deacetylase, acts through FOXO/DAF-16 transcription factor to prolong life. Recent studies show that mammalian SIR2 deacetylates FOXO, and may maximize survival by tempering cell death and increasing stress resistance.
SN - 1534-5807
UR - https://www.unboundmedicine.com/medline/citation/15030753/Tipping_the_balance_toward_longevity_
L2 - https://linkinghub.elsevier.com/retrieve/pii/S1534-5807(04)00068-1
DB - PRIME
DP - Unbound Medicine
ER -