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[News about therapeutic use of Cannabis and endocannabinoid system].
Med Clin (Barc) 2004; 122(10):390-8MC

Abstract

Growing basic research in recent years led to the discovery of the endocannabinoid system with a central role in neurobiology. New evidence suggests a therapeutic potential of cannabinoids in cancer chemotherapy-induced nausea and vomiting as well as in pain, spasticity and other symptoms in multiple sclerosis and movement disorders. Results of large randomized clinical trials of oral and sublingual Cannabis extracts will be known soon and there will be definitive answers to whether Cannabis has any therapeutic potential. Although the immediate future may lie in plant-based medicines, new targets for cannabinoid therapy focuses on the development of endocannabinoid degradation inhibitors which may offer site selectivity not afforded by cannabinoid receptor agonists.

Authors+Show Affiliations

Fundació Institut Català de Farmacologia, Hospital Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, España. mdd@icf.uab.esNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

spa

PubMed ID

15033046

Citation

Duran, Marta, et al. "[News About Therapeutic Use of Cannabis and Endocannabinoid System]." Medicina Clinica, vol. 122, no. 10, 2004, pp. 390-8.
Duran M, Laporte JR, Capellà D. [News about therapeutic use of Cannabis and endocannabinoid system]. Med Clin (Barc). 2004;122(10):390-8.
Duran, M., Laporte, J. R., & Capellà, D. (2004). [News about therapeutic use of Cannabis and endocannabinoid system]. Medicina Clinica, 122(10), pp. 390-8.
Duran M, Laporte JR, Capellà D. [News About Therapeutic Use of Cannabis and Endocannabinoid System]. Med Clin (Barc). 2004 Mar 20;122(10):390-8. PubMed PMID: 15033046.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [News about therapeutic use of Cannabis and endocannabinoid system]. AU - Duran,Marta, AU - Laporte,Joan-Ramon, AU - Capellà,Dolors, PY - 2004/3/23/pubmed PY - 2004/6/21/medline PY - 2004/3/23/entrez SP - 390 EP - 8 JF - Medicina clinica JO - Med Clin (Barc) VL - 122 IS - 10 N2 - Growing basic research in recent years led to the discovery of the endocannabinoid system with a central role in neurobiology. New evidence suggests a therapeutic potential of cannabinoids in cancer chemotherapy-induced nausea and vomiting as well as in pain, spasticity and other symptoms in multiple sclerosis and movement disorders. Results of large randomized clinical trials of oral and sublingual Cannabis extracts will be known soon and there will be definitive answers to whether Cannabis has any therapeutic potential. Although the immediate future may lie in plant-based medicines, new targets for cannabinoid therapy focuses on the development of endocannabinoid degradation inhibitors which may offer site selectivity not afforded by cannabinoid receptor agonists. SN - 0025-7753 UR - https://www.unboundmedicine.com/medline/citation/15033046/[News_about_therapeutic_use_of_Cannabis_and_endocannabinoid_system]_ L2 - http://www.elsevier.es/en/linksolver/ft/ivp/0025-7753/122/390 DB - PRIME DP - Unbound Medicine ER -