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Estimates of heterocyclic amine intake in the US population.

Abstract

HA-specific meat concentration estimates using a method that combines laboratory data to predict HA concentrations from meat type, cooking method and meat doneness were used with national dietary data to estimate daily HA intake for segments of the US population. PhIP was found to comprise approximately 70% of US mean dietary intake of total HAs, with pan-frying and chicken being the single cooking method and meat type contributing the greatest to total estimated HA exposures. This analysis demonstrated significantly higher concentrations in grilled/barbecued meats than in other cooked meats. African-American males were estimated to consume nearly twofold and approximately 35 to 40% more PhIP (and total HAs) than white males at ages <16 and >30 years, respectively.

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  • Authors+Show Affiliations

    ,

    Environmental Sciences Division (L-396), Lawrence Livermore National Laboratory, 7000 East Avenue, Livermore, CA 94550-9900, USA. keating2@llnl.gov

    Source

    MeSH

    Adolescent
    Adult
    Amines
    Food
    Heterocyclic Compounds
    Humans
    United States

    Pub Type(s)

    Journal Article
    Research Support, U.S. Gov't, Non-P.H.S.
    Research Support, U.S. Gov't, P.H.S.

    Language

    eng

    PubMed ID

    15036004

    Citation

    Keating, G A., and K T. Bogen. "Estimates of Heterocyclic Amine Intake in the US Population." Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, vol. 802, no. 1, 2004, pp. 127-33.
    Keating GA, Bogen KT. Estimates of heterocyclic amine intake in the US population. J Chromatogr B Analyt Technol Biomed Life Sci. 2004;802(1):127-33.
    Keating, G. A., & Bogen, K. T. (2004). Estimates of heterocyclic amine intake in the US population. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 802(1), pp. 127-33.
    Keating GA, Bogen KT. Estimates of Heterocyclic Amine Intake in the US Population. J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Mar 25;802(1):127-33. PubMed PMID: 15036004.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Estimates of heterocyclic amine intake in the US population. AU - Keating,G A, AU - Bogen,K T, PY - 2004/3/24/pubmed PY - 2004/9/29/medline PY - 2004/3/24/entrez SP - 127 EP - 33 JF - Journal of chromatography. B, Analytical technologies in the biomedical and life sciences JO - J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. VL - 802 IS - 1 N2 - HA-specific meat concentration estimates using a method that combines laboratory data to predict HA concentrations from meat type, cooking method and meat doneness were used with national dietary data to estimate daily HA intake for segments of the US population. PhIP was found to comprise approximately 70% of US mean dietary intake of total HAs, with pan-frying and chicken being the single cooking method and meat type contributing the greatest to total estimated HA exposures. This analysis demonstrated significantly higher concentrations in grilled/barbecued meats than in other cooked meats. African-American males were estimated to consume nearly twofold and approximately 35 to 40% more PhIP (and total HAs) than white males at ages <16 and >30 years, respectively. SN - 1570-0232 UR - https://www.unboundmedicine.com/medline/citation/15036004/full_citation L2 - https://linkinghub.elsevier.com/retrieve/pii/S1570023203008778 DB - PRIME DP - Unbound Medicine ER -