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Antihepatotoxic effect of Nymphaea stellata willd., against carbon tetrachloride-induced hepatic damage in albino rats.
J Ethnopharmacol. 2004 Mar; 91(1):61-4.JE

Abstract

Nymphaea stellata willd., a medicinal plant mentioned in Ayurveda for the treatment of liver disorders, has not been subjected to systematic scientific investigations to asses its hepatoprotective effects. Therefore, the present study was undertaken to investigate the hepatoprotective activity of extract of Nymphaea stellata willd., flower against carbon tetrachloride-induced hepatic damage in albino rats. The oral administration of varying dosage of extract of Nymphaea stellata willd., flower to rats for 10 days afforded the good hepatoprotection against carbon tetrachloride-induced elevation in serum marker enzymes, serum bilirubin, liver lipid peroxidation and reduction in liver glutathione, liver glutathione peroxidase, glycogen, superoxide dismutase and catalase activity.

Authors+Show Affiliations

Department of Biochemistry, Nagpur University, LIT Premises, Amravati Road, Nagpur 440010, India.No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15036469

Citation

Bhandarkar, Manoj R., and Aqueel Khan. "Antihepatotoxic Effect of Nymphaea Stellata Willd., Against Carbon Tetrachloride-induced Hepatic Damage in Albino Rats." Journal of Ethnopharmacology, vol. 91, no. 1, 2004, pp. 61-4.
Bhandarkar MR, Khan A. Antihepatotoxic effect of Nymphaea stellata willd., against carbon tetrachloride-induced hepatic damage in albino rats. J Ethnopharmacol. 2004;91(1):61-4.
Bhandarkar, M. R., & Khan, A. (2004). Antihepatotoxic effect of Nymphaea stellata willd., against carbon tetrachloride-induced hepatic damage in albino rats. Journal of Ethnopharmacology, 91(1), 61-4.
Bhandarkar MR, Khan A. Antihepatotoxic Effect of Nymphaea Stellata Willd., Against Carbon Tetrachloride-induced Hepatic Damage in Albino Rats. J Ethnopharmacol. 2004;91(1):61-4. PubMed PMID: 15036469.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antihepatotoxic effect of Nymphaea stellata willd., against carbon tetrachloride-induced hepatic damage in albino rats. AU - Bhandarkar,Manoj R, AU - Khan,Aqueel, PY - 2003/04/16/received PY - 2003/05/28/revised PY - 2003/11/21/accepted PY - 2004/3/24/pubmed PY - 2004/7/21/medline PY - 2004/3/24/entrez SP - 61 EP - 4 JF - Journal of ethnopharmacology JO - J Ethnopharmacol VL - 91 IS - 1 N2 - Nymphaea stellata willd., a medicinal plant mentioned in Ayurveda for the treatment of liver disorders, has not been subjected to systematic scientific investigations to asses its hepatoprotective effects. Therefore, the present study was undertaken to investigate the hepatoprotective activity of extract of Nymphaea stellata willd., flower against carbon tetrachloride-induced hepatic damage in albino rats. The oral administration of varying dosage of extract of Nymphaea stellata willd., flower to rats for 10 days afforded the good hepatoprotection against carbon tetrachloride-induced elevation in serum marker enzymes, serum bilirubin, liver lipid peroxidation and reduction in liver glutathione, liver glutathione peroxidase, glycogen, superoxide dismutase and catalase activity. SN - 0378-8741 UR - https://www.unboundmedicine.com/medline/citation/15036469/Antihepatotoxic_effect_of_Nymphaea_stellata_willd__against_carbon_tetrachloride_induced_hepatic_damage_in_albino_rats_ DB - PRIME DP - Unbound Medicine ER -