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Clinical considerations in premenopausal osteoporosis.
Arch Intern Med 2004; 164(6):603-14AI

Abstract

Osteoporosis can occur at any age. In premenopausal osteoporosis, full achievement of peak bone mass may be curtailed, and accelerated bone loss may occur in young adulthood. Premenopausal osteoporosis may be associated with chronic glucocorticoid therapy, prolonged amenorrhea, anorexia nervosa, rheumatoid arthritis, and diseases that affect calcium and vitamin D metabolism. Lesser degrees of bone loss may be associated with common conditions such as dieting, low calcium intake, smoking, and oligomenorrhea. Owing to a paucity of prospective studies on screening and treatment in younger age groups, few practice recommendations exist to guide the management of osteoporosis in young adults. We review the most important clinical concerns in premenopausal osteoporosis, including measurement of bone mass, normal bone accrual, risk factors for premature bone loss, clinical outcomes, and management issues. We emphasize clinically relevant information for primary care physicians, who are usually the first to encounter premenopausal patients with risk factors for early bone loss.

Authors+Show Affiliations

Department of Family Medicine, Robert Wood Johnson Clinical Scholars Program, University of North Carolina-Chapel Hill, 27599, USA. margaret-gourlay@med.unc.eduNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Review

Language

eng

PubMed ID

15037488

Citation

Gourlay, Margaret L., and Sue A. Brown. "Clinical Considerations in Premenopausal Osteoporosis." Archives of Internal Medicine, vol. 164, no. 6, 2004, pp. 603-14.
Gourlay ML, Brown SA. Clinical considerations in premenopausal osteoporosis. Arch Intern Med. 2004;164(6):603-14.
Gourlay, M. L., & Brown, S. A. (2004). Clinical considerations in premenopausal osteoporosis. Archives of Internal Medicine, 164(6), pp. 603-14.
Gourlay ML, Brown SA. Clinical Considerations in Premenopausal Osteoporosis. Arch Intern Med. 2004 Mar 22;164(6):603-14. PubMed PMID: 15037488.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical considerations in premenopausal osteoporosis. AU - Gourlay,Margaret L, AU - Brown,Sue A, PY - 2004/3/24/pubmed PY - 2004/4/23/medline PY - 2004/3/24/entrez SP - 603 EP - 14 JF - Archives of internal medicine JO - Arch. Intern. Med. VL - 164 IS - 6 N2 - Osteoporosis can occur at any age. In premenopausal osteoporosis, full achievement of peak bone mass may be curtailed, and accelerated bone loss may occur in young adulthood. Premenopausal osteoporosis may be associated with chronic glucocorticoid therapy, prolonged amenorrhea, anorexia nervosa, rheumatoid arthritis, and diseases that affect calcium and vitamin D metabolism. Lesser degrees of bone loss may be associated with common conditions such as dieting, low calcium intake, smoking, and oligomenorrhea. Owing to a paucity of prospective studies on screening and treatment in younger age groups, few practice recommendations exist to guide the management of osteoporosis in young adults. We review the most important clinical concerns in premenopausal osteoporosis, including measurement of bone mass, normal bone accrual, risk factors for premature bone loss, clinical outcomes, and management issues. We emphasize clinically relevant information for primary care physicians, who are usually the first to encounter premenopausal patients with risk factors for early bone loss. SN - 0003-9926 UR - https://www.unboundmedicine.com/medline/citation/15037488/Clinical_considerations_in_premenopausal_osteoporosis_ L2 - https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/10.1001/archinte.164.6.603 DB - PRIME DP - Unbound Medicine ER -