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Pathogenic Escherichia coli.
Nat Rev Microbiol. 2004 Feb; 2(2):123-40.NR

Abstract

Few microorganisms are as versatile as Escherichia coli. An important member of the normal intestinal microflora of humans and other mammals, E. coli has also been widely exploited as a cloning host in recombinant DNA technology. But E. coli is more than just a laboratory workhorse or harmless intestinal inhabitant; it can also be a highly versatile, and frequently deadly, pathogen. Several different E. coli strains cause diverse intestinal and extraintestinal diseases by means of virulence factors that affect a wide range of cellular processes.

Authors+Show Affiliations

Kaper JB
Center for Vaccine Development, Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA. jkaper@umaryland.edu
Nataro JP
No affiliation info available
Mobley HL
No affiliation info available

MeSH

AnimalsBacterial AdhesionDiarrheaEscherichia coliGene Expression Regulation, BacterialHumansMeningitis, BacterialShiga ToxinsUrinary Tract InfectionsVirulence Factors

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.
Review

Language

eng

PubMed ID

15040260

Citation

Kaper, James B., et al. "Pathogenic Escherichia Coli." Nature Reviews. Microbiology, vol. 2, no. 2, 2004, pp. 123-40.
Kaper JB, Nataro JP, Mobley HL. Pathogenic Escherichia coli. Nat Rev Microbiol. 2004;2(2):123-40.
Kaper, J. B., Nataro, J. P., & Mobley, H. L. (2004). Pathogenic Escherichia coli. Nature Reviews. Microbiology, 2(2), 123-40.
Kaper JB, Nataro JP, Mobley HL. Pathogenic Escherichia Coli. Nat Rev Microbiol. 2004;2(2):123-40. PubMed PMID: 15040260.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pathogenic Escherichia coli. AU - Kaper,James B, AU - Nataro,James P, AU - Mobley,Harry L, PY - 2004/3/26/pubmed PY - 2004/4/9/medline PY - 2004/3/26/entrez SP - 123 EP - 40 JF - Nature reviews. Microbiology JO - Nat Rev Microbiol VL - 2 IS - 2 N2 - Few microorganisms are as versatile as Escherichia coli. An important member of the normal intestinal microflora of humans and other mammals, E. coli has also been widely exploited as a cloning host in recombinant DNA technology. But E. coli is more than just a laboratory workhorse or harmless intestinal inhabitant; it can also be a highly versatile, and frequently deadly, pathogen. Several different E. coli strains cause diverse intestinal and extraintestinal diseases by means of virulence factors that affect a wide range of cellular processes. SN - 1740-1526 UR - https://www.unboundmedicine.com/medline/citation/15040260/full_citation L2 - https://doi.org/10.1038/nrmicro818 DB - PRIME DP - Unbound Medicine ER -