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Pathogenic Escherichia coli.
Nat Rev Microbiol. 2004 Feb; 2(2):123-40.NR

Abstract

Few microorganisms are as versatile as Escherichia coli. An important member of the normal intestinal microflora of humans and other mammals, E. coli has also been widely exploited as a cloning host in recombinant DNA technology. But E. coli is more than just a laboratory workhorse or harmless intestinal inhabitant; it can also be a highly versatile, and frequently deadly, pathogen. Several different E. coli strains cause diverse intestinal and extraintestinal diseases by means of virulence factors that affect a wide range of cellular processes.

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  • Publisher Full Text

    • Authors+Show Affiliations

    Kaper JB
    Center for Vaccine Development, Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA. jkaper@umaryland.edu
    Nataro JP
    No affiliation info available
    Mobley HL
    No affiliation info available

    MeSH

    AnimalsBacterial AdhesionDiarrheaEscherichia coliGene Expression Regulation, BacterialHumansMeningitis, BacterialShiga ToxinsUrinary Tract InfectionsVirulence Factors

    Pub Type(s)

    Journal Article
    Research Support, U.S. Gov't, P.H.S.
    Review

    Language

    eng

    PubMed ID

    15040260

    Citation

    Kaper, James B., et al. "Pathogenic Escherichia Coli." Nature Reviews. Microbiology, vol. 2, no. 2, 2004, pp. 123-40.
    Kaper JB, Nataro JP, Mobley HL. Pathogenic Escherichia coli. Nat Rev Microbiol. 2004;2(2):123-40.
    Kaper, J. B., Nataro, J. P., & Mobley, H. L. (2004). Pathogenic Escherichia coli. Nature Reviews. Microbiology, 2(2), 123-40.
    Kaper JB, Nataro JP, Mobley HL. Pathogenic Escherichia Coli. Nat Rev Microbiol. 2004;2(2):123-40. PubMed PMID: 15040260.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Pathogenic Escherichia coli. AU - Kaper,James B, AU - Nataro,James P, AU - Mobley,Harry L, PY - 2004/3/26/pubmed PY - 2004/4/9/medline PY - 2004/3/26/entrez SP - 123 EP - 40 JF - Nature reviews. Microbiology JO - Nat. Rev. Microbiol. VL - 2 IS - 2 N2 - Few microorganisms are as versatile as Escherichia coli. An important member of the normal intestinal microflora of humans and other mammals, E. coli has also been widely exploited as a cloning host in recombinant DNA technology. But E. coli is more than just a laboratory workhorse or harmless intestinal inhabitant; it can also be a highly versatile, and frequently deadly, pathogen. Several different E. coli strains cause diverse intestinal and extraintestinal diseases by means of virulence factors that affect a wide range of cellular processes. SN - 1740-1526 UR - https://www.unboundmedicine.com/medline/citation/15040260/full_citation L2 - http://dx.doi.org/10.1038/nrmicro818 DB - PRIME DP - Unbound Medicine ER -