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Bedside ketone determination in diabetic children with hyperglycemia and ketosis in the acute care setting.
Pediatr Diabetes 2004; 5(1):39-43PD

Abstract

OBJECTIVE

Diabetic ketoacidosis (DKA) is a serious complication of diabetes mellitus marked by characteristic biochemical derangements. Diagnosis and management involve frequent evaluation of these biochemical parameters. Reliable bedside equivalents for these laboratory studies may help reduce the time to treatment and reduce costs.

METHODS

We evaluated the precision and bias of a bedside serum ketone meter in the acute care setting. Serum ketone results using the Precision Xtra glucometer/ketone meter (Abbott Laboratories, MediSense Products Inc., Bedford, MA, USA) correlated strongly with the Children's Medical Center of Dallas' laboratory values within the meter's value range.

RESULTS

Meter ketone values steadily decreased during the treatment of DKA as pH and CO(2) levels increased and acidosis resolved.

CONCLUSION

Therefore, the meter may be useful in monitoring therapy for DKA. This meter may also prove useful in identifying patients at risk for DKA in physicians' offices or at home.

Authors+Show Affiliations

Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390-9063, USA. melham@childmed.dallas.tx.usNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

15043689

Citation

Ham, Melissa R., et al. "Bedside Ketone Determination in Diabetic Children With Hyperglycemia and Ketosis in the Acute Care Setting." Pediatric Diabetes, vol. 5, no. 1, 2004, pp. 39-43.
Ham MR, Okada P, White PC. Bedside ketone determination in diabetic children with hyperglycemia and ketosis in the acute care setting. Pediatr Diabetes. 2004;5(1):39-43.
Ham, M. R., Okada, P., & White, P. C. (2004). Bedside ketone determination in diabetic children with hyperglycemia and ketosis in the acute care setting. Pediatric Diabetes, 5(1), pp. 39-43.
Ham MR, Okada P, White PC. Bedside Ketone Determination in Diabetic Children With Hyperglycemia and Ketosis in the Acute Care Setting. Pediatr Diabetes. 2004;5(1):39-43. PubMed PMID: 15043689.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Bedside ketone determination in diabetic children with hyperglycemia and ketosis in the acute care setting. AU - Ham,Melissa R, AU - Okada,Pamela, AU - White,Perrin C, PY - 2004/3/27/pubmed PY - 2004/11/13/medline PY - 2004/3/27/entrez SP - 39 EP - 43 JF - Pediatric diabetes JO - Pediatr Diabetes VL - 5 IS - 1 N2 - OBJECTIVE: Diabetic ketoacidosis (DKA) is a serious complication of diabetes mellitus marked by characteristic biochemical derangements. Diagnosis and management involve frequent evaluation of these biochemical parameters. Reliable bedside equivalents for these laboratory studies may help reduce the time to treatment and reduce costs. METHODS: We evaluated the precision and bias of a bedside serum ketone meter in the acute care setting. Serum ketone results using the Precision Xtra glucometer/ketone meter (Abbott Laboratories, MediSense Products Inc., Bedford, MA, USA) correlated strongly with the Children's Medical Center of Dallas' laboratory values within the meter's value range. RESULTS: Meter ketone values steadily decreased during the treatment of DKA as pH and CO(2) levels increased and acidosis resolved. CONCLUSION: Therefore, the meter may be useful in monitoring therapy for DKA. This meter may also prove useful in identifying patients at risk for DKA in physicians' offices or at home. SN - 1399-543X UR - https://www.unboundmedicine.com/medline/citation/15043689/Bedside_ketone_determination_in_diabetic_children_with_hyperglycemia_and_ketosis_in_the_acute_care_setting_ L2 - https://doi.org/10.1111/j.1399-543X.2004.00032.x DB - PRIME DP - Unbound Medicine ER -