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Right ventricular strain rate and strain analysis in patients with repaired tetralogy of Fallot: possible interventricular septal compensation.
J Am Soc Echocardiogr. 2004 Apr; 17(4):338-44.JA

Abstract

BACKGROUND

Indices such as strain rate (SR) and strain (epsilon) are free of geometric assumptions and, thus, may provide new insights into right ventricular (RV) function and compensatory mechanisms in repaired tetralogy of Fallot (TOF).

METHODS

All those with postoperative (>1 year) TOF had echocardiography evaluation of SR and epsilon indices along the RV lateral free wall (RVFW) and the interventricular septum (IVS) in the apical 4-chamber view. Pulmonary regurgitation, pulmonary stenosis, QRS duration, RV ejection fraction, and RV dimension were also measured and compared with control subjects.

RESULTS

There were 15 patients with TOF (7 +/- 4 years old) 6 +/- 3 years remote from surgical repair and 25 control subjects (10 +/- 5 years old). In the patients with TOF, systolic and diastolic SR and epsilon in the RVFW were significantly reduced but were normal in the IVS. In the RVFW, reduced systolic SR and epsilon correlated with reduced RV ejection fraction (r = -0.7 [P <.01] and -0.6 [P <.03], respectively), and poorer early diastolic SR correlated with poorer RV ejection fraction (r = 0.7, P <.01).

CONCLUSIONS

In patients with postoperative TOF, systolic and diastolic RV SR and epsilon were impaired in the RVFW but preserved in the IVS. We speculate that IVS myocardial function is preserved as a compensatory mechanism for impaired RVFW function.

Authors+Show Affiliations

Cincinnati Children's Hospital Medical Center, OH 45229-3039, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Evaluation Study
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

15044867

Citation

Solarz, David E., et al. "Right Ventricular Strain Rate and Strain Analysis in Patients With Repaired Tetralogy of Fallot: Possible Interventricular Septal Compensation." Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography, vol. 17, no. 4, 2004, pp. 338-44.
Solarz DE, Witt SA, Glascock BJ, et al. Right ventricular strain rate and strain analysis in patients with repaired tetralogy of Fallot: possible interventricular septal compensation. J Am Soc Echocardiogr. 2004;17(4):338-44.
Solarz, D. E., Witt, S. A., Glascock, B. J., Jones, F. D., Khoury, P. R., & Kimball, T. R. (2004). Right ventricular strain rate and strain analysis in patients with repaired tetralogy of Fallot: possible interventricular septal compensation. Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography, 17(4), 338-44.
Solarz DE, et al. Right Ventricular Strain Rate and Strain Analysis in Patients With Repaired Tetralogy of Fallot: Possible Interventricular Septal Compensation. J Am Soc Echocardiogr. 2004;17(4):338-44. PubMed PMID: 15044867.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Right ventricular strain rate and strain analysis in patients with repaired tetralogy of Fallot: possible interventricular septal compensation. AU - Solarz,David E, AU - Witt,Sandra A, AU - Glascock,Betty J, AU - Jones,Frederick D, AU - Khoury,Philip R, AU - Kimball,Thomas R, PY - 2004/3/27/pubmed PY - 2004/11/9/medline PY - 2004/3/27/entrez SP - 338 EP - 44 JF - Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography JO - J Am Soc Echocardiogr VL - 17 IS - 4 N2 - BACKGROUND: Indices such as strain rate (SR) and strain (epsilon) are free of geometric assumptions and, thus, may provide new insights into right ventricular (RV) function and compensatory mechanisms in repaired tetralogy of Fallot (TOF). METHODS: All those with postoperative (>1 year) TOF had echocardiography evaluation of SR and epsilon indices along the RV lateral free wall (RVFW) and the interventricular septum (IVS) in the apical 4-chamber view. Pulmonary regurgitation, pulmonary stenosis, QRS duration, RV ejection fraction, and RV dimension were also measured and compared with control subjects. RESULTS: There were 15 patients with TOF (7 +/- 4 years old) 6 +/- 3 years remote from surgical repair and 25 control subjects (10 +/- 5 years old). In the patients with TOF, systolic and diastolic SR and epsilon in the RVFW were significantly reduced but were normal in the IVS. In the RVFW, reduced systolic SR and epsilon correlated with reduced RV ejection fraction (r = -0.7 [P <.01] and -0.6 [P <.03], respectively), and poorer early diastolic SR correlated with poorer RV ejection fraction (r = 0.7, P <.01). CONCLUSIONS: In patients with postoperative TOF, systolic and diastolic RV SR and epsilon were impaired in the RVFW but preserved in the IVS. We speculate that IVS myocardial function is preserved as a compensatory mechanism for impaired RVFW function. SN - 0894-7317 UR - https://www.unboundmedicine.com/medline/citation/15044867/Right_ventricular_strain_rate_and_strain_analysis_in_patients_with_repaired_tetralogy_of_Fallot:_possible_interventricular_septal_compensation_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0894731704000884 DB - PRIME DP - Unbound Medicine ER -