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[Evaluation of genotoxicity of sodium hypochlorite, chlorine dioxide and peracetic acid using plant tests].
Ann Ig. 2003 Nov-Dec; 15(6):959-63.AI

Abstract

The aim of this research was to evaluate the potential genotoxic effects of three drinking water disinfectants by means of in vivo short-term mutagenicity tests using plants. The study was carried out in laboratory using distilled water disinfected with sodium hypochlorite (NaClO), chlorine dioxide (ClO2) and peracetic acid (PAA) at different concentrations both in neutral and acid conditions. Untreated distilled water was used as a negative control. Micronuclei test in Tradescantia pollen cells and chromosomal aberration test in root cells of Allium cepa were the bioassays performed by exposing directly plant bioindicators to treated and untreated distilled water. The Tradescantia/micronuclei test gave positive results in most of the ClO2-treated water samples but only at acid pH. The Allium cepa test showed genotoxicity in NaClO-treated samples at acid pH and in a ClO2-treated sample at pH 7. PAA-treated samples were always nongenotoxic. Since the concentrations tested of free disinfectants are usually present in drinking water for biocidal purposes, genotoxicity of these compounds could be a public health problem.

Authors+Show Affiliations

Dipartimento di Medicina Sperimentale ed Applicata, Università degli Studi di Brescia.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

ita

PubMed ID

15049554

Citation

Feretti, D, et al. "[Evaluation of Genotoxicity of Sodium Hypochlorite, Chlorine Dioxide and Peracetic Acid Using Plant Tests]." Annali Di Igiene : Medicina Preventiva E Di Comunita, vol. 15, no. 6, 2003, pp. 959-63.
Feretti D, Zani C, Alberti A, et al. [Evaluation of genotoxicity of sodium hypochlorite, chlorine dioxide and peracetic acid using plant tests]. Ann Ig. 2003;15(6):959-63.
Feretti, D., Zani, C., Alberti, A., Copetta, L., Nardi, G., & Monarca, S. (2003). [Evaluation of genotoxicity of sodium hypochlorite, chlorine dioxide and peracetic acid using plant tests]. Annali Di Igiene : Medicina Preventiva E Di Comunita, 15(6), 959-63.
Feretti D, et al. [Evaluation of Genotoxicity of Sodium Hypochlorite, Chlorine Dioxide and Peracetic Acid Using Plant Tests]. Ann Ig. 2003 Nov-Dec;15(6):959-63. PubMed PMID: 15049554.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Evaluation of genotoxicity of sodium hypochlorite, chlorine dioxide and peracetic acid using plant tests]. AU - Feretti,D, AU - Zani,C, AU - Alberti,A, AU - Copetta,L, AU - Nardi,G, AU - Monarca,S, PY - 2004/3/31/pubmed PY - 2004/9/1/medline PY - 2004/3/31/entrez SP - 959 EP - 63 JF - Annali di igiene : medicina preventiva e di comunita JO - Ann Ig VL - 15 IS - 6 N2 - The aim of this research was to evaluate the potential genotoxic effects of three drinking water disinfectants by means of in vivo short-term mutagenicity tests using plants. The study was carried out in laboratory using distilled water disinfected with sodium hypochlorite (NaClO), chlorine dioxide (ClO2) and peracetic acid (PAA) at different concentrations both in neutral and acid conditions. Untreated distilled water was used as a negative control. Micronuclei test in Tradescantia pollen cells and chromosomal aberration test in root cells of Allium cepa were the bioassays performed by exposing directly plant bioindicators to treated and untreated distilled water. The Tradescantia/micronuclei test gave positive results in most of the ClO2-treated water samples but only at acid pH. The Allium cepa test showed genotoxicity in NaClO-treated samples at acid pH and in a ClO2-treated sample at pH 7. PAA-treated samples were always nongenotoxic. Since the concentrations tested of free disinfectants are usually present in drinking water for biocidal purposes, genotoxicity of these compounds could be a public health problem. SN - 1120-9135 UR - https://www.unboundmedicine.com/medline/citation/15049554/[Evaluation_of_genotoxicity_of_sodium_hypochlorite_chlorine_dioxide_and_peracetic_acid_using_plant_tests]_ DB - PRIME DP - Unbound Medicine ER -