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Quantitative analysis of the flavonoids in raw propolis from northern Croatia.
Acta Pharm. 2004 Mar; 54(1):65-72.AP

Abstract

Spectrometric analyses of flavonoids in twenty propolis samples, collected from ten different geographic localities in northern Croatia using two complementary methods, are reported. Flavones and flavonols were determined using aluminum chloride and expressed as quercetine equivalent while flavanones were determined using 2,4-dinitrophenylhydrazine and expressed as naringenin. Contents of flavones and flavonols were similar for most samples and ranged from 2 to 2.3%, except for one sample with a concentration of 1.3% and one sample in which it was not possible to detect flavones and flavonols. The content of flavanones in propolis samples is very variable. 55% of samples contained flavanones between 15 and 24% and 45% of samples between 4 and 14%. Total levels of flavonoids in raw propolis samples ranged between 5 and 26%; for the majority of samples (75%), the total level of flavonoids ranged between 15 and 25.9%. The high variability of flavanone concentration will affect the biological activity of propolis preparations.

Authors+Show Affiliations

Institute of Microbiology, Faculty of Pharmacy and Biochemistry, University of Zagreb, HR-10000 Zagreb, Croatia. ivan.kosalec@zg.htnet.hrNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15050046

Citation

Kosalec, Ivan, et al. "Quantitative Analysis of the Flavonoids in Raw Propolis From Northern Croatia." Acta Pharmaceutica (Zagreb, Croatia), vol. 54, no. 1, 2004, pp. 65-72.
Kosalec I, Bakmaz M, Pepeljnjak S, et al. Quantitative analysis of the flavonoids in raw propolis from northern Croatia. Acta Pharm. 2004;54(1):65-72.
Kosalec, I., Bakmaz, M., Pepeljnjak, S., & Vladimir-Knezević, S. (2004). Quantitative analysis of the flavonoids in raw propolis from northern Croatia. Acta Pharmaceutica (Zagreb, Croatia), 54(1), 65-72.
Kosalec I, et al. Quantitative Analysis of the Flavonoids in Raw Propolis From Northern Croatia. Acta Pharm. 2004;54(1):65-72. PubMed PMID: 15050046.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Quantitative analysis of the flavonoids in raw propolis from northern Croatia. AU - Kosalec,Ivan, AU - Bakmaz,Marina, AU - Pepeljnjak,Stjepan, AU - Vladimir-Knezević,Sanda, PY - 2004/3/31/pubmed PY - 2004/12/16/medline PY - 2004/3/31/entrez SP - 65 EP - 72 JF - Acta pharmaceutica (Zagreb, Croatia) JO - Acta Pharm VL - 54 IS - 1 N2 - Spectrometric analyses of flavonoids in twenty propolis samples, collected from ten different geographic localities in northern Croatia using two complementary methods, are reported. Flavones and flavonols were determined using aluminum chloride and expressed as quercetine equivalent while flavanones were determined using 2,4-dinitrophenylhydrazine and expressed as naringenin. Contents of flavones and flavonols were similar for most samples and ranged from 2 to 2.3%, except for one sample with a concentration of 1.3% and one sample in which it was not possible to detect flavones and flavonols. The content of flavanones in propolis samples is very variable. 55% of samples contained flavanones between 15 and 24% and 45% of samples between 4 and 14%. Total levels of flavonoids in raw propolis samples ranged between 5 and 26%; for the majority of samples (75%), the total level of flavonoids ranged between 15 and 25.9%. The high variability of flavanone concentration will affect the biological activity of propolis preparations. SN - 1330-0075 UR - https://www.unboundmedicine.com/medline/citation/15050046/Quantitative_analysis_of_the_flavonoids_in_raw_propolis_from_northern_Croatia_ DB - PRIME DP - Unbound Medicine ER -