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Influence of optic edge design and anterior capsule polishing on posterior capsule fibrosis.
J Cataract Refract Surg. 2004 Mar; 30(3):658-62.JC

Abstract

PURPOSE

To evaluate the role of posterior optic edge design and the effect of anterior capsule polishing on peripheral fibrotic posterior capsule opacification (PCO).

SETTING

Department of Ophthalmology, University of Vienna, Vienna, Austria.

METHODS

This randomized prospective study comprised 144 eyes of 72 patients with bilateral age-related cataract. Each patient had standardized cataract surgery in both eyes by the same surgeon. Group 1 (46 patients) received a round-edged hydrophobic acrylic IOL (AMO Sensar AR40) in 1 eye and a sharp-edged hydrophobic acrylic IOL (AMO Sensar OptiEdge AR40e) in the other eye. Group 2 (26 patients) received a silicone IOL (Pharmacia CeeOn 911A) with a truncated optic in both eyes. In this group, the anterior capsule was extensively polished in 1 eye and was left unpolished in the other eye. Digital slitlamp photographs were taken 1 year postoperatively using a standardized photographic technique for fibrotic PCO. The intensity of PCO was subjectively graded (score 0 to 4) by 2 masked examiners.

RESULTS

Subjective PCO scores correlated well between the 2 examiners (r = 0.88). In Group 1, the mean PCO score was 0.26 for the OptiEdge AR40e IOL and 0.90 for the AR40 IOL (P<.01). In Group 2, the mean PCO score was 0.24 in eyes with a polished capsule and 0.17 in eyes in which the capsule was not polished (P =.31).

CONCLUSIONS

The sharp-edged OptiEdge AR40e IOL led to significantly less peripheral fibrotic PCO 1 year postoperatively than the round-edged AR40 IOL. In eyes with the sharp-edged silicone 911A IOL, anterior capsule polishing caused no significant difference in fibrotic PCO.

Authors+Show Affiliations

Department of Ophthalmology, University of Vienna, Vienna, Austria.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

15050264

Citation

Sacu, Stefan, et al. "Influence of Optic Edge Design and Anterior Capsule Polishing On Posterior Capsule Fibrosis." Journal of Cataract and Refractive Surgery, vol. 30, no. 3, 2004, pp. 658-62.
Sacu S, Menapace R, Findl O, et al. Influence of optic edge design and anterior capsule polishing on posterior capsule fibrosis. J Cataract Refract Surg. 2004;30(3):658-62.
Sacu, S., Menapace, R., Findl, O., Georgopoulos, M., Buehl, W., Kriechbaum, K., & Rainer, G. (2004). Influence of optic edge design and anterior capsule polishing on posterior capsule fibrosis. Journal of Cataract and Refractive Surgery, 30(3), 658-62.
Sacu S, et al. Influence of Optic Edge Design and Anterior Capsule Polishing On Posterior Capsule Fibrosis. J Cataract Refract Surg. 2004;30(3):658-62. PubMed PMID: 15050264.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Influence of optic edge design and anterior capsule polishing on posterior capsule fibrosis. AU - Sacu,Stefan, AU - Menapace,Rupert, AU - Findl,Oliver, AU - Georgopoulos,Michael, AU - Buehl,Wolf, AU - Kriechbaum,Katharina, AU - Rainer,Georg, PY - 2003/07/11/accepted PY - 2004/3/31/pubmed PY - 2004/6/21/medline PY - 2004/3/31/entrez SP - 658 EP - 62 JF - Journal of cataract and refractive surgery JO - J Cataract Refract Surg VL - 30 IS - 3 N2 - PURPOSE: To evaluate the role of posterior optic edge design and the effect of anterior capsule polishing on peripheral fibrotic posterior capsule opacification (PCO). SETTING: Department of Ophthalmology, University of Vienna, Vienna, Austria. METHODS: This randomized prospective study comprised 144 eyes of 72 patients with bilateral age-related cataract. Each patient had standardized cataract surgery in both eyes by the same surgeon. Group 1 (46 patients) received a round-edged hydrophobic acrylic IOL (AMO Sensar AR40) in 1 eye and a sharp-edged hydrophobic acrylic IOL (AMO Sensar OptiEdge AR40e) in the other eye. Group 2 (26 patients) received a silicone IOL (Pharmacia CeeOn 911A) with a truncated optic in both eyes. In this group, the anterior capsule was extensively polished in 1 eye and was left unpolished in the other eye. Digital slitlamp photographs were taken 1 year postoperatively using a standardized photographic technique for fibrotic PCO. The intensity of PCO was subjectively graded (score 0 to 4) by 2 masked examiners. RESULTS: Subjective PCO scores correlated well between the 2 examiners (r = 0.88). In Group 1, the mean PCO score was 0.26 for the OptiEdge AR40e IOL and 0.90 for the AR40 IOL (P<.01). In Group 2, the mean PCO score was 0.24 in eyes with a polished capsule and 0.17 in eyes in which the capsule was not polished (P =.31). CONCLUSIONS: The sharp-edged OptiEdge AR40e IOL led to significantly less peripheral fibrotic PCO 1 year postoperatively than the round-edged AR40 IOL. In eyes with the sharp-edged silicone 911A IOL, anterior capsule polishing caused no significant difference in fibrotic PCO. SN - 0886-3350 UR - https://www.unboundmedicine.com/medline/citation/15050264/Influence_of_optic_edge_design_and_anterior_capsule_polishing_on_posterior_capsule_fibrosis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S088633500300720X DB - PRIME DP - Unbound Medicine ER -