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Awareness of folic acid for prevention of neural tube defects in a community with high prevalence of consanguineous marriages.
Ann Genet. 2004 Jan-Mar; 47(1):69-75.AG

Abstract

Neural tube defects (NTDs) are severe congenital malformations and can be fatal. Intake of 0.4 mg folic in the periconceptional period reduces the risk of NTD by 50-70%. Consanguinity in the Arab population in Israel is a prevalent custom. The aim of this study was to assess the level of awareness regarding folic acid and its effect in the prevention of NTD among Arab Israeli women of childbearing age. We conducted a cross-sectional study. Of the 653 women (18-45 years) who were randomly selected for interview while visiting their family physician or well-baby clinic, 624 women completed the questionnaire. Fifty-three percent (n = 333) of the respondents had heard of folic acid; 14% (n = 89) were familiar with the protective effect of NTD and 3% (n = 18) had taken folic acid in the first months of pregnancy whereas none of them had used it in the preconception period. Highly educated women, women with one or two children, paramedics, and women of high socioeconomic status were more knowledgeable about the protective effects of folic acid (P < 0.001). Age and religion had no significant effect. An urgent need exists to improve the awareness of this population to the protective effect of folic acid. Daily supplementation and fertification of food with folic acid should be considered as the best way to improve the balance of folic acid in women of childbearing age of this special population (high prevalence of consanguinity).

Authors+Show Affiliations

The Bridge to Peace Community Pediatric Center, P.O. Box 27, Taibe 40400, Israel. jabe@bezeqint.netNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15050876

Citation

Jaber, Lutfi, et al. "Awareness of Folic Acid for Prevention of Neural Tube Defects in a Community With High Prevalence of Consanguineous Marriages." Annales De Genetique, vol. 47, no. 1, 2004, pp. 69-75.
Jaber L, Karim IA, Jawdat AM, et al. Awareness of folic acid for prevention of neural tube defects in a community with high prevalence of consanguineous marriages. Ann Genet. 2004;47(1):69-75.
Jaber, L., Karim, I. A., Jawdat, A. M., Fausi, M., & Merlob, P. (2004). Awareness of folic acid for prevention of neural tube defects in a community with high prevalence of consanguineous marriages. Annales De Genetique, 47(1), 69-75.
Jaber L, et al. Awareness of Folic Acid for Prevention of Neural Tube Defects in a Community With High Prevalence of Consanguineous Marriages. Ann Genet. 2004 Jan-Mar;47(1):69-75. PubMed PMID: 15050876.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Awareness of folic acid for prevention of neural tube defects in a community with high prevalence of consanguineous marriages. AU - Jaber,Lutfi, AU - Karim,Igbaria A, AU - Jawdat,Abu Moch, AU - Fausi,Mawasi, AU - Merlob,Paul, PY - 2003/05/30/received PY - 2003/08/21/accepted PY - 2004/3/31/pubmed PY - 2004/12/24/medline PY - 2004/3/31/entrez SP - 69 EP - 75 JF - Annales de genetique JO - Ann Genet VL - 47 IS - 1 N2 - Neural tube defects (NTDs) are severe congenital malformations and can be fatal. Intake of 0.4 mg folic in the periconceptional period reduces the risk of NTD by 50-70%. Consanguinity in the Arab population in Israel is a prevalent custom. The aim of this study was to assess the level of awareness regarding folic acid and its effect in the prevention of NTD among Arab Israeli women of childbearing age. We conducted a cross-sectional study. Of the 653 women (18-45 years) who were randomly selected for interview while visiting their family physician or well-baby clinic, 624 women completed the questionnaire. Fifty-three percent (n = 333) of the respondents had heard of folic acid; 14% (n = 89) were familiar with the protective effect of NTD and 3% (n = 18) had taken folic acid in the first months of pregnancy whereas none of them had used it in the preconception period. Highly educated women, women with one or two children, paramedics, and women of high socioeconomic status were more knowledgeable about the protective effects of folic acid (P < 0.001). Age and religion had no significant effect. An urgent need exists to improve the awareness of this population to the protective effect of folic acid. Daily supplementation and fertification of food with folic acid should be considered as the best way to improve the balance of folic acid in women of childbearing age of this special population (high prevalence of consanguinity). SN - 0003-3995 UR - https://www.unboundmedicine.com/medline/citation/15050876/Awareness_of_folic_acid_for_prevention_of_neural_tube_defects_in_a_community_with_high_prevalence_of_consanguineous_marriages_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0003399503000698 DB - PRIME DP - Unbound Medicine ER -