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Cigar smoking has an acute detrimental effect on arterial stiffness.
Am J Hypertens 2004; 17(4):299-303AJ

Abstract

BACKGROUND

Despite a decline in cigarette smoking, cigar smoking is increasing, partly due to the perception that it is a "safe" alternative to cigarettes. However, cigar smoking increases cardiovascular risk, but the mechanisms involved are not fully explored. Aortic stiffness and arterial wave reflection are important factors for the efficient performance of the cardiovascular system and have been identified as prognosticators of cardiovascular risk. We investigated the acute effect of cigar smoking on aortic elastic properties and wave reflection.

METHODS

We studied the effect of smoking one cigar in 12 healthy subjects according to a randomized, sham procedure-controlled, cross-over design. Aortic stiffness was evaluated with carotid-femoral pulse wave velocity and wave reflection with augmentation index of the aortic pressure waveform.

RESULTS

Cigar smoking produced a significant increase in pulse wave velocity (by 0.80 m/sec, P = .001) denoting an increase in aortic stiffness. Augmentation index increased significantly (by 6.1%, P < .05) denoting an increase of wave reflections. These increases in arterial stiffness indices were evident promptly after the initiation of cigar smoking and lasted throughout the duration of the study (2 h). Concurrently, both radial and aortic systolic, and pulse pressure increased significantly throughout the study.

CONCLUSIONS

The present study shows for the first time that cigar smoking increases acutely stiffness of large arteries and wave reflection, thus providing further evidence that it is not a safe alternative to cigarettes.

Authors+Show Affiliations

Athens Medical School, Hippokration Hospital, Athens, Greece. cvlachop@otenet.grNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

15062882

Citation

Vlachopoulos, Charalambos, et al. "Cigar Smoking Has an Acute Detrimental Effect On Arterial Stiffness." American Journal of Hypertension, vol. 17, no. 4, 2004, pp. 299-303.
Vlachopoulos C, Alexopoulos N, Panagiotakos D, et al. Cigar smoking has an acute detrimental effect on arterial stiffness. Am J Hypertens. 2004;17(4):299-303.
Vlachopoulos, C., Alexopoulos, N., Panagiotakos, D., O'Rourke, M. F., & Stefanadis, C. (2004). Cigar smoking has an acute detrimental effect on arterial stiffness. American Journal of Hypertension, 17(4), pp. 299-303.
Vlachopoulos C, et al. Cigar Smoking Has an Acute Detrimental Effect On Arterial Stiffness. Am J Hypertens. 2004;17(4):299-303. PubMed PMID: 15062882.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cigar smoking has an acute detrimental effect on arterial stiffness. AU - Vlachopoulos,Charalambos, AU - Alexopoulos,Nikolaos, AU - Panagiotakos,Demosthenes, AU - O'Rourke,Michael F, AU - Stefanadis,Christodoulos, PY - 2003/10/14/received PY - 2003/12/23/revised PY - 2003/12/23/accepted PY - 2004/4/6/pubmed PY - 2004/11/9/medline PY - 2004/4/6/entrez SP - 299 EP - 303 JF - American journal of hypertension JO - Am. J. Hypertens. VL - 17 IS - 4 N2 - BACKGROUND: Despite a decline in cigarette smoking, cigar smoking is increasing, partly due to the perception that it is a "safe" alternative to cigarettes. However, cigar smoking increases cardiovascular risk, but the mechanisms involved are not fully explored. Aortic stiffness and arterial wave reflection are important factors for the efficient performance of the cardiovascular system and have been identified as prognosticators of cardiovascular risk. We investigated the acute effect of cigar smoking on aortic elastic properties and wave reflection. METHODS: We studied the effect of smoking one cigar in 12 healthy subjects according to a randomized, sham procedure-controlled, cross-over design. Aortic stiffness was evaluated with carotid-femoral pulse wave velocity and wave reflection with augmentation index of the aortic pressure waveform. RESULTS: Cigar smoking produced a significant increase in pulse wave velocity (by 0.80 m/sec, P = .001) denoting an increase in aortic stiffness. Augmentation index increased significantly (by 6.1%, P < .05) denoting an increase of wave reflections. These increases in arterial stiffness indices were evident promptly after the initiation of cigar smoking and lasted throughout the duration of the study (2 h). Concurrently, both radial and aortic systolic, and pulse pressure increased significantly throughout the study. CONCLUSIONS: The present study shows for the first time that cigar smoking increases acutely stiffness of large arteries and wave reflection, thus providing further evidence that it is not a safe alternative to cigarettes. SN - 0895-7061 UR - https://www.unboundmedicine.com/medline/citation/15062882/Cigar_smoking_has_an_acute_detrimental_effect_on_arterial_stiffness_ L2 - https://academic.oup.com/ajh/article-lookup/doi/10.1016/j.amjhyper.2003.12.014 DB - PRIME DP - Unbound Medicine ER -