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Pentagon drawing and neuropsychological performance in Dementia with Lewy Bodies, Alzheimer's disease, Parkinson's disease and Parkinson's disease with dementia.
Int J Geriatr Psychiatry. 2004 Apr; 19(4):371-7.IJ

Abstract

OBJECTIVES

Early and accurate diagnosis of Dementia with Lewy Bodies (DLB) to allow the appropriate clinical treatment is a priority, given reports of severe neuroleptic sensitivity and a preferential response to cholinesterase inhibitors in these patients. There have been suggestions that constructional apraxia is prevalent in DLB, and may provide a sensitive marker of the disease.

METHODS

This study examined the pentagon drawings of 100 DLB patients, 50 Alzheimer's disease (AD) patients, 81 Parkinson's disease (PD) patients of whom 36 suffered from dementia (PDD). Performance on this task was correlated with cognitive performance on the MMSE and CAMCOG scales.

RESULTS

Patients with DLB were found to draw significantly worse pentagons than those with AD or PD, but not those with PDD. Drawing scores were significantly correlated with MMSE scores for the AD and PDD groups but not those with DLB. More detailed analysis of the neuropsychological correlates of constructional performance for patients with AD and DLB, revealed that those with AD showed a broad cognitive basis to their impairment, in DLB drawing was linked only to perception and praxis.

CONCLUSIONS

This study has suggests that DLB subjects show an impairment of pentagon copying that is dissociable from more global cognitive impairments, whereas PD patients are relatively unimpaired on pentagon copying and AD and PDD patients show a linkage of their impairment in copying with more global cognitive deficits.

Authors+Show Affiliations

Psychology Department, The Henry Wellcome Building For Neuroecology, Framlington Place, Newcastle University, Newcastle Upon Tyne, UK.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15065231

Citation

Cormack, Francesca, et al. "Pentagon Drawing and Neuropsychological Performance in Dementia With Lewy Bodies, Alzheimer's Disease, Parkinson's Disease and Parkinson's Disease With Dementia." International Journal of Geriatric Psychiatry, vol. 19, no. 4, 2004, pp. 371-7.
Cormack F, Aarsland D, Ballard C, et al. Pentagon drawing and neuropsychological performance in Dementia with Lewy Bodies, Alzheimer's disease, Parkinson's disease and Parkinson's disease with dementia. Int J Geriatr Psychiatry. 2004;19(4):371-7.
Cormack, F., Aarsland, D., Ballard, C., & Tovée, M. J. (2004). Pentagon drawing and neuropsychological performance in Dementia with Lewy Bodies, Alzheimer's disease, Parkinson's disease and Parkinson's disease with dementia. International Journal of Geriatric Psychiatry, 19(4), 371-7.
Cormack F, et al. Pentagon Drawing and Neuropsychological Performance in Dementia With Lewy Bodies, Alzheimer's Disease, Parkinson's Disease and Parkinson's Disease With Dementia. Int J Geriatr Psychiatry. 2004;19(4):371-7. PubMed PMID: 15065231.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pentagon drawing and neuropsychological performance in Dementia with Lewy Bodies, Alzheimer's disease, Parkinson's disease and Parkinson's disease with dementia. AU - Cormack,Francesca, AU - Aarsland,Dag, AU - Ballard,Clive, AU - Tovée,Martin J, PY - 2004/4/6/pubmed PY - 2004/6/25/medline PY - 2004/4/6/entrez SP - 371 EP - 7 JF - International journal of geriatric psychiatry JO - Int J Geriatr Psychiatry VL - 19 IS - 4 N2 - OBJECTIVES: Early and accurate diagnosis of Dementia with Lewy Bodies (DLB) to allow the appropriate clinical treatment is a priority, given reports of severe neuroleptic sensitivity and a preferential response to cholinesterase inhibitors in these patients. There have been suggestions that constructional apraxia is prevalent in DLB, and may provide a sensitive marker of the disease. METHODS: This study examined the pentagon drawings of 100 DLB patients, 50 Alzheimer's disease (AD) patients, 81 Parkinson's disease (PD) patients of whom 36 suffered from dementia (PDD). Performance on this task was correlated with cognitive performance on the MMSE and CAMCOG scales. RESULTS: Patients with DLB were found to draw significantly worse pentagons than those with AD or PD, but not those with PDD. Drawing scores were significantly correlated with MMSE scores for the AD and PDD groups but not those with DLB. More detailed analysis of the neuropsychological correlates of constructional performance for patients with AD and DLB, revealed that those with AD showed a broad cognitive basis to their impairment, in DLB drawing was linked only to perception and praxis. CONCLUSIONS: This study has suggests that DLB subjects show an impairment of pentagon copying that is dissociable from more global cognitive impairments, whereas PD patients are relatively unimpaired on pentagon copying and AD and PDD patients show a linkage of their impairment in copying with more global cognitive deficits. SN - 0885-6230 UR - https://www.unboundmedicine.com/medline/citation/15065231/Pentagon_drawing_and_neuropsychological_performance_in_Dementia_with_Lewy_Bodies_Alzheimer's_disease_Parkinson's_disease_and_Parkinson's_disease_with_dementia_ L2 - https://doi.org/10.1002/gps.1094 DB - PRIME DP - Unbound Medicine ER -