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Enzymatic synthesis of multi-component copolymers and their structural characterization.
Mol Divers. 2003; 6(3-4):287-95.MD

Abstract

The use of enzymes in synthetic applications has increased dramatically in the recent years and the field of polymer science is part of this trend. Synthesis of a variety of polymers using lipase catalyzed (Candida antarctica) polymerization reactions has led to a variety of new materials with interesting properties in our laboratories. This paper describes the synthesis of multi-component polyesters and mixed polymers having polyester and polyamide linkages under solvent-less conditions using Candida antarctica lipase B. The effect of a third component, i.e. a series of 1,omega-alkanediols (1,4-butanediol, 1,6-hexanediol, 1,8-octanediol, 1,10-decanediol, 1,12-dodecanediol, 1,14-tetradecanediol and 1,16-hexadecanediol) on the copolymerization reaction of dimethyl 5-hydroxyisophthalate with poly(ethylene glycol 600) has been studied and the mechanism for the incorporation of the third component is proposed. We have also studied the effect of different functional groups during terpolymerization reaction of dimethyl 5-hydroxyisophthalate with poly(ethylene glycol) by adding a third component having different functionalities (1,6-hexanediol, 1,6-hexanediamine or 1,6-hexanedithiol) and compared the effect of hydroxyl, amine and thiol groups on the polymerization reactions.

Authors+Show Affiliations

Institute for Nano Science and Engineering Technology, Department of Chemistry, University of Massachusetts Lowell, MA 01854, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15068093

Citation

Kumar, Rajesh, et al. "Enzymatic Synthesis of Multi-component Copolymers and Their Structural Characterization." Molecular Diversity, vol. 6, no. 3-4, 2003, pp. 287-95.
Kumar R, Tyagi R, Parmar VS, et al. Enzymatic synthesis of multi-component copolymers and their structural characterization. Mol Divers. 2003;6(3-4):287-95.
Kumar, R., Tyagi, R., Parmar, V. S., Samuelson, L. A., Kumar, J., & Watterson, A. C. (2003). Enzymatic synthesis of multi-component copolymers and their structural characterization. Molecular Diversity, 6(3-4), 287-95.
Kumar R, et al. Enzymatic Synthesis of Multi-component Copolymers and Their Structural Characterization. Mol Divers. 2003;6(3-4):287-95. PubMed PMID: 15068093.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Enzymatic synthesis of multi-component copolymers and their structural characterization. AU - Kumar,Rajesh, AU - Tyagi,Rahul, AU - Parmar,Virinder S, AU - Samuelson,Lynne A, AU - Kumar,Jayant, AU - Watterson,Arthur C, PY - 2004/4/8/pubmed PY - 2004/10/13/medline PY - 2004/4/8/entrez SP - 287 EP - 95 JF - Molecular diversity JO - Mol. Divers. VL - 6 IS - 3-4 N2 - The use of enzymes in synthetic applications has increased dramatically in the recent years and the field of polymer science is part of this trend. Synthesis of a variety of polymers using lipase catalyzed (Candida antarctica) polymerization reactions has led to a variety of new materials with interesting properties in our laboratories. This paper describes the synthesis of multi-component polyesters and mixed polymers having polyester and polyamide linkages under solvent-less conditions using Candida antarctica lipase B. The effect of a third component, i.e. a series of 1,omega-alkanediols (1,4-butanediol, 1,6-hexanediol, 1,8-octanediol, 1,10-decanediol, 1,12-dodecanediol, 1,14-tetradecanediol and 1,16-hexadecanediol) on the copolymerization reaction of dimethyl 5-hydroxyisophthalate with poly(ethylene glycol 600) has been studied and the mechanism for the incorporation of the third component is proposed. We have also studied the effect of different functional groups during terpolymerization reaction of dimethyl 5-hydroxyisophthalate with poly(ethylene glycol) by adding a third component having different functionalities (1,6-hexanediol, 1,6-hexanediamine or 1,6-hexanedithiol) and compared the effect of hydroxyl, amine and thiol groups on the polymerization reactions. SN - 1381-1991 UR - https://www.unboundmedicine.com/medline/citation/15068093/Enzymatic_synthesis_of_multi_component_copolymers_and_their_structural_characterization_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=15068093.ui DB - PRIME DP - Unbound Medicine ER -