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Foetal facial clefts: prenatal evaluation of lip and primary palate by 2D and 3D ultrasound.
Ultraschall Med. 2004 Apr; 25(2):120-5.UM

Abstract

INTRODUCTION

To examine whether three-dimensional ultrasound (3D US) is an accurate diagnostic method of clinical use in the ability to define the location and extent of facial clefting prenatally, compared to two-dimensional ultrasound (2D US).

METHODS

18 foetuses suspected or diagnosed to suffer from a facial cleft by 2D US were examined with a targeted 3D US. 2D US and 3D US results were compared with postnatal outcome.

RESULTS

Comparison of the number of foetuses with a cleft lip + primary palate diagnosed correctly with 2D US with the results of adjunctive 3D US (true positive + true negative) showed that adjunctive 3D US correctly diagnosed more cleft lips (100 %; 15/15 foetuses vs. 66 %; 12/18 foetuses) and more cleft primary palates (100 %; 12/12 foetuses vs. 58 %; 7/12 foetuses).

CONCLUSION

Interactive review of standardised 3D multiplanar images allows to systematically evaluate lip defects and abnormalities of the maxillary tooth-bearing alveolar ridge. The accuracy of adjunctive 3D ultrasound is superior to 2D ultrasound alone for extensive prenatal diagnosis of cleft lip with or without cleft primary palate.

Authors+Show Affiliations

Department of Neonatology and Intensive Care, University Hospital of Vienna, Austria. Christoph.mittermayer@gyn.akh.magwien.gv.atNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15085453

Citation

Mittermayer, C, et al. "Foetal Facial Clefts: Prenatal Evaluation of Lip and Primary Palate By 2D and 3D Ultrasound." Ultraschall in Der Medizin (Stuttgart, Germany : 1980), vol. 25, no. 2, 2004, pp. 120-5.
Mittermayer C, Blaicher W, Brugger PC, et al. Foetal facial clefts: prenatal evaluation of lip and primary palate by 2D and 3D ultrasound. Ultraschall Med. 2004;25(2):120-5.
Mittermayer, C., Blaicher, W., Brugger, P. C., Bernaschek, G., & Lee, A. (2004). Foetal facial clefts: prenatal evaluation of lip and primary palate by 2D and 3D ultrasound. Ultraschall in Der Medizin (Stuttgart, Germany : 1980), 25(2), 120-5.
Mittermayer C, et al. Foetal Facial Clefts: Prenatal Evaluation of Lip and Primary Palate By 2D and 3D Ultrasound. Ultraschall Med. 2004;25(2):120-5. PubMed PMID: 15085453.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Foetal facial clefts: prenatal evaluation of lip and primary palate by 2D and 3D ultrasound. AU - Mittermayer,C, AU - Blaicher,W, AU - Brugger,P C, AU - Bernaschek,G, AU - Lee,A, PY - 2004/4/16/pubmed PY - 2004/7/15/medline PY - 2004/4/16/entrez SP - 120 EP - 5 JF - Ultraschall in der Medizin (Stuttgart, Germany : 1980) JO - Ultraschall Med VL - 25 IS - 2 N2 - INTRODUCTION: To examine whether three-dimensional ultrasound (3D US) is an accurate diagnostic method of clinical use in the ability to define the location and extent of facial clefting prenatally, compared to two-dimensional ultrasound (2D US). METHODS: 18 foetuses suspected or diagnosed to suffer from a facial cleft by 2D US were examined with a targeted 3D US. 2D US and 3D US results were compared with postnatal outcome. RESULTS: Comparison of the number of foetuses with a cleft lip + primary palate diagnosed correctly with 2D US with the results of adjunctive 3D US (true positive + true negative) showed that adjunctive 3D US correctly diagnosed more cleft lips (100 %; 15/15 foetuses vs. 66 %; 12/18 foetuses) and more cleft primary palates (100 %; 12/12 foetuses vs. 58 %; 7/12 foetuses). CONCLUSION: Interactive review of standardised 3D multiplanar images allows to systematically evaluate lip defects and abnormalities of the maxillary tooth-bearing alveolar ridge. The accuracy of adjunctive 3D ultrasound is superior to 2D ultrasound alone for extensive prenatal diagnosis of cleft lip with or without cleft primary palate. SN - 0172-4614 UR - https://www.unboundmedicine.com/medline/citation/15085453/Foetal_facial_clefts:_prenatal_evaluation_of_lip_and_primary_palate_by_2D_and_3D_ultrasound_ L2 - https://www.thieme-connect.com/DOI/DOI?10.1055/s-2004-813102 DB - PRIME DP - Unbound Medicine ER -