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Combination of BMI and Waist Circumference for Identifying Cardiovascular Risk Factors in Whites.
Obes Res. 2004 Apr; 12(4):633-45.OR

Abstract

OBJECTIVE

BMI (kilograms per meters squared) and waist circumference (WC) (measured in centimeters) are each associated with the risk of developing cardiovascular disease (CVD). Therefore, a combination of the two may be more effective in identifying subjects at risk than either alone. The present study sought to identify the combination of BMI and WC that has the strongest association with CVD risk factors in whites.

RESEARCH METHODS AND PROCEDURES

Subjects were 8712 white men and women from the Third National Health and Nutrition Examination Survey. The optimal combination of BMI and WC was developed using logistic regression models with BMI and WC as predictors and CVD risk factors as outcomes. The combined measure of BMI and WC using current cut-off points was also examined. Sensitivity, specificity, and receiver operating characteristics curves were compared between the combined measures and BMI alone.

RESULTS

For white men, the optimal combination of BMI and WC for identifying CVD risk factors was 0.68 x BMI + 0.32 x WC. This combination generated a score that better estimated the odds of having CVD risk factors than either alone. For white women, WC alone largely determined the likelihood of having CVD risks. The combination of BMI and WC using current cut-off points may provide an improved measure of CVD risk. Combined measures showed a higher sensitivity or a shorter distance in receiver operating characteristic curves in the identification of CVD risk factors.

DISCUSSION

Combined measures of BMI and WC may provide a higher overall test performance for CVD risk factors and may be useful in some ethnic groups as an improved means of screening subjects for further evaluation in the clinical setting.

Authors+Show Affiliations

New York Obesity Research Center, St. Luke's-Roosevelt Hospital Center and Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, USA. szhu@mcw.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

15090631

Citation

Zhu, Shankuan, et al. "Combination of BMI and Waist Circumference for Identifying Cardiovascular Risk Factors in Whites." Obesity Research, vol. 12, no. 4, 2004, pp. 633-45.
Zhu S, Heshka S, Wang Z, et al. Combination of BMI and Waist Circumference for Identifying Cardiovascular Risk Factors in Whites. Obes Res. 2004;12(4):633-45.
Zhu, S., Heshka, S., Wang, Z., Shen, W., Allison, D. B., Ross, R., & Heymsfield, S. B. (2004). Combination of BMI and Waist Circumference for Identifying Cardiovascular Risk Factors in Whites. Obesity Research, 12(4), 633-45.
Zhu S, et al. Combination of BMI and Waist Circumference for Identifying Cardiovascular Risk Factors in Whites. Obes Res. 2004;12(4):633-45. PubMed PMID: 15090631.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Combination of BMI and Waist Circumference for Identifying Cardiovascular Risk Factors in Whites. AU - Zhu,Shankuan, AU - Heshka,Stanley, AU - Wang,ZiMian, AU - Shen,Wei, AU - Allison,David B, AU - Ross,Robert, AU - Heymsfield,Steven B, PY - 2004/4/20/pubmed PY - 2004/7/17/medline PY - 2004/4/20/entrez SP - 633 EP - 45 JF - Obesity research JO - Obes Res VL - 12 IS - 4 N2 - OBJECTIVE: BMI (kilograms per meters squared) and waist circumference (WC) (measured in centimeters) are each associated with the risk of developing cardiovascular disease (CVD). Therefore, a combination of the two may be more effective in identifying subjects at risk than either alone. The present study sought to identify the combination of BMI and WC that has the strongest association with CVD risk factors in whites. RESEARCH METHODS AND PROCEDURES: Subjects were 8712 white men and women from the Third National Health and Nutrition Examination Survey. The optimal combination of BMI and WC was developed using logistic regression models with BMI and WC as predictors and CVD risk factors as outcomes. The combined measure of BMI and WC using current cut-off points was also examined. Sensitivity, specificity, and receiver operating characteristics curves were compared between the combined measures and BMI alone. RESULTS: For white men, the optimal combination of BMI and WC for identifying CVD risk factors was 0.68 x BMI + 0.32 x WC. This combination generated a score that better estimated the odds of having CVD risk factors than either alone. For white women, WC alone largely determined the likelihood of having CVD risks. The combination of BMI and WC using current cut-off points may provide an improved measure of CVD risk. Combined measures showed a higher sensitivity or a shorter distance in receiver operating characteristic curves in the identification of CVD risk factors. DISCUSSION: Combined measures of BMI and WC may provide a higher overall test performance for CVD risk factors and may be useful in some ethnic groups as an improved means of screening subjects for further evaluation in the clinical setting. SN - 1071-7323 UR - https://www.unboundmedicine.com/medline/citation/15090631/Combination_of_BMI_and_Waist_Circumference_for_Identifying_Cardiovascular_Risk_Factors_in_Whites_ L2 - https://doi.org/10.1038/oby.2004.73 DB - PRIME DP - Unbound Medicine ER -