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Seborrheic dermatitis of the scalp: etiology and treatment.
J Drugs Dermatol. 2004 Mar-Apr; 3(2):155-8.JD

Abstract

Seborrheic dermatitis is a common chronic infection of the lipid-rich areas of skin. While seborrheic dermatitis has been a recognized clinical entity for decades, its etiology is far from clear. Early investigators of the development of seborrheic dermatitis focused on the role of the Malassezia (previously Pityrosporum) yeasts. These yeasts are also normal skin commensals, thus their importance as pathogens in this disorder came to be doubted. However, it was subsequently found that treatment of seborrheic dermatitis with an antifungal agent not only resulted in clinical improvement but also reduced the number of Malassezia yeasts on the skin. This has resulted in a resurgence of interest in the Malassezia yeasts. It has been hypothesized that there is an immunological component to seborrheic dermatitis, possibly representing an abnormal host response to the Malassezia yeasts. This paper will discuss the role of Malassezia in the etiology of seborrheic dermatitis, as well as the various treatment options.

Authors+Show Affiliations

Gupta AK
Division of Dermatology, Department of Medicine, Sunnybrook and Women's College Health Science Center (Sunnybrook Site) and the University of Toronto, Toronto, Canada. agupta@execulink.com
Nicol KA
No affiliation info available

MeSH

Administration, TopicalAdultAntifungal AgentsDermatitis, SeborrheicFemaleHumansMalasseziaMaleScalp

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15098970

Citation

Gupta, Aditya K., and Karyn A. Nicol. "Seborrheic Dermatitis of the Scalp: Etiology and Treatment." Journal of Drugs in Dermatology : JDD, vol. 3, no. 2, 2004, pp. 155-8.
Gupta AK, Nicol KA. Seborrheic dermatitis of the scalp: etiology and treatment. J Drugs Dermatol. 2004;3(2):155-8.
Gupta, A. K., & Nicol, K. A. (2004). Seborrheic dermatitis of the scalp: etiology and treatment. Journal of Drugs in Dermatology : JDD, 3(2), 155-8.
Gupta AK, Nicol KA. Seborrheic Dermatitis of the Scalp: Etiology and Treatment. J Drugs Dermatol. 2004 Mar-Apr;3(2):155-8. PubMed PMID: 15098970.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Seborrheic dermatitis of the scalp: etiology and treatment. AU - Gupta,Aditya K, AU - Nicol,Karyn A, PY - 2004/4/22/pubmed PY - 2004/6/30/medline PY - 2004/4/22/entrez SP - 155 EP - 8 JF - Journal of drugs in dermatology : JDD JO - J Drugs Dermatol VL - 3 IS - 2 N2 - Seborrheic dermatitis is a common chronic infection of the lipid-rich areas of skin. While seborrheic dermatitis has been a recognized clinical entity for decades, its etiology is far from clear. Early investigators of the development of seborrheic dermatitis focused on the role of the Malassezia (previously Pityrosporum) yeasts. These yeasts are also normal skin commensals, thus their importance as pathogens in this disorder came to be doubted. However, it was subsequently found that treatment of seborrheic dermatitis with an antifungal agent not only resulted in clinical improvement but also reduced the number of Malassezia yeasts on the skin. This has resulted in a resurgence of interest in the Malassezia yeasts. It has been hypothesized that there is an immunological component to seborrheic dermatitis, possibly representing an abnormal host response to the Malassezia yeasts. This paper will discuss the role of Malassezia in the etiology of seborrheic dermatitis, as well as the various treatment options. SN - 1545-9616 UR - https://www.unboundmedicine.com/medline/citation/15098970/Seborrheic_dermatitis_of_the_scalp:_etiology_and_treatment_ DB - PRIME DP - Unbound Medicine ER -