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Composition and bioactivity of the leaf essential oil of Heteropyxis dehniae from Zimbabwe.
J Ethnopharmacol. 2004 May; 92(1):107-11.JE

Abstract

The leaf oil of Heteropyxis dehniae Suess. (Heteropyxidaceae) was obtained by hydrodistillation and analyzed by GC/MS. The most abundant essential oil components are linalool (58.3%), 4-terpineol (9.8%), alpha-terpineol (3.6%), and caryophyllene oxide (3.1%). The antimicrobial activity against Bacillus cereus, Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Candida albicans, and Aspergillus niger, and the in vitro cytotoxicity of the oil on PC-3, MDA-MB-231, Hs 578T, MCF7, SK-MEL-28, and 5637 human tumor cells were also examined. Caryophyllene oxide shows notable cytotoxic activity with LC50 values of 147-351 microM.

Authors+Show Affiliations

Department of Chemistry, University of Zimbabwe, Box MP 167, Harare, Zimbabwe.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

15099856

Citation

Sibanda, Samson, et al. "Composition and Bioactivity of the Leaf Essential Oil of Heteropyxis Dehniae From Zimbabwe." Journal of Ethnopharmacology, vol. 92, no. 1, 2004, pp. 107-11.
Sibanda S, Chigwada G, Poole M, et al. Composition and bioactivity of the leaf essential oil of Heteropyxis dehniae from Zimbabwe. J Ethnopharmacol. 2004;92(1):107-11.
Sibanda, S., Chigwada, G., Poole, M., Gwebu, E. T., Noletto, J. A., Schmidt, J. M., Rea, A. I., & Setzer, W. N. (2004). Composition and bioactivity of the leaf essential oil of Heteropyxis dehniae from Zimbabwe. Journal of Ethnopharmacology, 92(1), 107-11.
Sibanda S, et al. Composition and Bioactivity of the Leaf Essential Oil of Heteropyxis Dehniae From Zimbabwe. J Ethnopharmacol. 2004;92(1):107-11. PubMed PMID: 15099856.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Composition and bioactivity of the leaf essential oil of Heteropyxis dehniae from Zimbabwe. AU - Sibanda,Samson, AU - Chigwada,Grace, AU - Poole,Melvin, AU - Gwebu,Ephraim T, AU - Noletto,Joseph A, AU - Schmidt,Jennifer M, AU - Rea,Angela I, AU - Setzer,William N, PY - 2003/11/13/received PY - 2004/02/03/accepted PY - 2004/4/22/pubmed PY - 2004/6/25/medline PY - 2004/4/22/entrez SP - 107 EP - 11 JF - Journal of ethnopharmacology JO - J Ethnopharmacol VL - 92 IS - 1 N2 - The leaf oil of Heteropyxis dehniae Suess. (Heteropyxidaceae) was obtained by hydrodistillation and analyzed by GC/MS. The most abundant essential oil components are linalool (58.3%), 4-terpineol (9.8%), alpha-terpineol (3.6%), and caryophyllene oxide (3.1%). The antimicrobial activity against Bacillus cereus, Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Candida albicans, and Aspergillus niger, and the in vitro cytotoxicity of the oil on PC-3, MDA-MB-231, Hs 578T, MCF7, SK-MEL-28, and 5637 human tumor cells were also examined. Caryophyllene oxide shows notable cytotoxic activity with LC50 values of 147-351 microM. SN - 0378-8741 UR - https://www.unboundmedicine.com/medline/citation/15099856/Composition_and_bioactivity_of_the_leaf_essential_oil_of_Heteropyxis_dehniae_from_Zimbabwe_ DB - PRIME DP - Unbound Medicine ER -